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Adult hematopoietic stem cells (HSCs) reside in bone marrow and are maintained in a dormant state within a special microenvironment, their so-called "niche". Detaching from the niche induces cell cycle progression, resulting in a reduction of the reconstitution capacity of HSCs. In contrast, fetal liver HSCs actively divide without losing their stem cell potentials. Thus, it has been unclear what

The harm that pathogens cause to hosts during infection, termed virulence, varies across species from negligible to a high likelihood of rapid death. Classic theory for the evolution of virulence is based on a trade-off between pathogen growth, transmission and host survival, which predicts that higher within-host growth causes increased transmission and higher virulence. However, using data from

November 2011 saw the opening of the exhibition "Archeovirtual" organized by CNR ITABC - Virtual Heritage Lab - and V-MusT Network of Excellence, in Paestum, Italy, under the general direction of BMTA1. The event, that was part of a wider European project focus on virtual museums, turned to be a great opportunity to show many different projects, applications and installations about Virtual Reality

Den sjungande trappuppgången är en TV-serie i sex avsnitt på SVT med start 6 februari 2012. Med inspiration från engelsk förlaga handlar serien om experimentet, att samla en större grupp människor med olika ålder och bakgrund, boende i samma förortsstadsdel utan större kontakt med sina grannar, och tillsammans bilda en sångkör med målet att uppträda vid offentliga konserter.

Genetic susceptibility, environmental factors and immune mechanisms are implicated in the pathogenesis and etiology of insulindependent diabetes mellitus. The onset of the disease is associated with a major loss of beta cells, and inflammatory cells may be seen in and around the islets of Langerhans. Insulin-dependent diabetes is often associated with autoimmune endocrinopathies. Antipancreatic ce

This article explores how a series of heritage-driven renewal plans in the Swedish city Malmö dealt with a landscape deeply shaped by radical politics: Malmö People’s Park (Folkets Park). Arguing against notions of heritage where the past is essentially considered a malleable resource for present commercial or political concerns, we scrutinise plans for the People’s Park from the 1980s onward to e

One of the most puzzling passages of Vergil's Aeneid is the last lines of book VI where Aeneas and the Sibyl leave the underworld through the gate of ivory, the gate of false dreams. "Few passages of the Aeneid have given rise to more controversies and divergence of judgement" (Brooks Otis). In this article we analyse the linguistic context and propose a new solution to the problem.

We investigated possible motivations for sound symbolism in spatial demonstratives within 101 areally and genetically diverse languages. Six different predictions were formulated on the basis of factors such as (a) semiotic ground (iconic, indexical or combined), (b) speaker-centered, hearer-centered or both and (c) applicable to vowels, consonants or both. Each one of these six predictions result