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There is growing evidence that lay health workers providing counselling is a feasible approach of addressing the universally large treatment gap for mental disorders. This study illuminates the experiences of the counsellors in the Youth Friendship Bench in Zimbabwe, a pilot project where students provide problem-solving therapy to adolescents with common mental disorders. Twelve interviews were a

Plasma levels of intact parathyroid hormone (PTH) were measured intraoperatively before and after removal of one enlarged gland in 20 hyperparathyroid patients. In 13 patients with a single parathyroid adenoma, plasma levels of intact PTH-(1-84) had declined at 15 min after removal of the adenoma by 86.5 +/- 4.4% of baseline in the antecubital vein and by 85.6 +/- 4.2% in the ipsilateral internal

Background: In order to contain public health care spending, European countries attempt to promote informal caregiving. However, such a cost reducing strategy will only be successful if informal caregiving is a substitute for formal health care services. We therefore analyze the effect of informal caregiving for people with dementia on the use of several formal health care services. Study design:

Different ways of viewing human-nature interactions affect the ways in which these are conceptualized and operationalized with regards to cultural ecosystem services (CES). To clarify if some conceptualizations provide more appropriate descriptions of benefits, these need to be discussed in relation to the lived experience. This paper addresses some aspects of the controversy around the use of the

The release of methane from crater sites following meteorite impact is a possible consequence of the thermal alteration of organic matter, or tapping of reservoired gas of biogenic or abiogenic origin. At least the latter is feasible on Mars. Methane and higher hydrocarbons are susceptible to polymerization and precipitation by radioactive minerals. Where such minerals are present in impact target

This paper presents a dedicated search for exotic decays of the Higgs boson to a pair of new spin-zero particles, H→ aa, where the particle a decays to b-quarks and has a mass in the range of 20–60 GeV. The search is performed in events where the Higgs boson is produced in association with a W boson, giving rise to a signature of a lepton (electron or muon), missing transverse momentum, and multip

Cytochromes of the c type contain covalently bound heme. In bacteria, they are located on the outside of the cytoplasmic membrane. Cytochrome c synthesis involves export of heme and apocytochrome across the cytoplasmic membrane followed by ligation of heme to the polypeptide. Using radioactive protoheme IX produced in Escherichia coli, we show that Bacillus subtilis can use heme from the growth me

A search is conducted for both resonant and non-resonant high-mass new phenomena in dielectron and dimuon final states. The search uses 3.2fb−1 of proton–proton collision data, collected at s=13TeV by the ATLAS experiment at the LHC in 2015. The dilepton invariant mass is used as the discriminating variable. No significant deviation from the Standard Model prediction is observed; therefore limits

A search for the standard model Higgs boson produced in association with a vector boson with the decay H→ττ is presented. The data correspond to 20.3 fb-1 of integrated luminosity from proton-proton collisions at s=8 TeV recorded by the ATLAS experiment at the LHC during 2012. The data agree with the background expectation, and 95% confidence-level upper limits are placed on the cross section of t

Apolipoprotein A-I (apoA-I) is the major protein constituent of high density lipoprotein (HDL) and plays a central role in phospholipid and cholesterol metabolism. This 243-residue long protein is remarkably flexible and assumes numerous lipid-dependent conformations. Consequently, definitive structural determination of lipid-free apoA-I in solution has been difficult. Using electron paramagnetic

Background: Diabetic foot ulcers are a common and severe complication of diabetes mellitus. Standard treatment includes debridement, offloading, management of infection and revascularisation where appropriate, although healing times may be long. The LeucoPatch® device is used to generate an autologous platelet-rich fibrin and leucocyte wound dressing produced from the patient's own venous blood by