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Importance: Patients with melanoma are selected for sentinel lymph node biopsy (SLNB) based on their risk of a positive SLN. To improve selection, the Memorial Sloan Kettering Cancer Center (MSKCC) and Melanoma Institute Australia (MIA) developed predictive models, but the utility of these models remains to be tested. Objective: To determine the clinical utility of the MIA and MSKCC models. Design

Deep learning has allowed for remarkable progress in many medical scenarios. Deep learning prediction models often require 105–107 examples. It is currently unknown whether deep learning can also enhance predictions of symptoms post-stroke in real-world samples of stroke patients that are often several magnitudes smaller. Such stroke outcome predictions however could be particularly instrumental i

Almost 30 years have passed since the dismantling of South Africa’s apartheid system, putting an end to the long history of racial segregation, discrimination, and oppression. But has it really changed? This research highlights the emergence of Black Economic Empowerment (BEE) as an affirmative policy instrument to advance land reform and rectify the enduring inequalities in the country’s agricult

The geology of Vombsänkan is characterized by a complex sequence of Quaternary deposits overlying the Paleozoic sedimentary bedrock. The area is 759 km2 and has recorded several ice advances followed by glacial retreats and ice melting. The glacial history of Vombsänkan, which is controlled by sequential geological events such as active ice-margin and stagnant ice, formation of dead ice as well as

With aging populations, unequal access to care, and shortages of staff, healthcare systems today are facing many challenges. Technology advancements, with artificial intelligence (AI) in particular, have been one of the main drivers of innovation in multiple industries. Although the healthcare sector is moving slower compared to other industries, there is great potential for relieving healthcare w

This thesis investigates the narratives Icelandic politicians use to discuss crime, particularly focusing on themes of cultural purity and danger. The study aims to understand how these narratives influence public perception and policy. Politicians often frame crime as a significant threat to societal norms and values, using various rhetorical strategies to evoke emotions such as fear and urgency.

Soft power and public diplomacy compose the new reality shaping the dynamics of contemporary international relations. Strategic narratives represent an essential means for political actors to extend their influence, gain the public opinion’s support for their actions and fulfill their foreign policy goals. The thesis focused on the Chinese Party state’s construction of strategic narratives targete

This master’s thesis aims to support product-centered companies in their transition to a circular economy (CE) by developing a digital self-assessment and decision support tool. Circularity is a complex field that demands collaboration across multiple system levels. Although a wide range of frameworks, regulations and guidelines exist, the transition remains difficult for companies to navigate. Ex

In most manufacturing companies, it is necessary to carry inventory to a greater or lesser extent in order to disconnect the activities in the supply chain that are not conducted at the same pace. This way, a smoother flow through the chain, from raw material extraction to arrival at the final customer of a finished product, is facilitated. However, different parts of a company often have conflict

A deprioritization of economic growth in policy making in the rich countries will need to be part of a global effort to re-embed economy and society into planetary boundaries. However, societal support for a degrowth transition remains for the time being moderate, and it is not well understood as yet why this is the case. This article argues that Pierre Bourdieu’s sociology can help theorize socie

Various less-toxic substitutes for the Pb2+-based perovskites have been proposed, of which Sn2+-based metal halide perovskites (namely, Sn-PVSKs) hold the best prospects because of their optoelectronic properties comparable to those of the Pb analogues. Nevertheless, the intrinsic instability and unfavorable crystallization of Sn-PVSKs place restrictions on both the device performance/durability a

This article analyzes administrative practices in relation to the emergence of novel technologies. “Smart mobility” is an umbrella term used to denote the potentially disruptive changes in the transport sector relating to automatization, digitalization, and the platform economy. While this development is largely driven by industry, public administrations are engaging in a number of processes where

The possibility of prosecuting serious international crimes before domestic foreign courts when territorial courts are unwilling and unable to perform this function and international criminal tribunals with suitable competences are unavailable has been intensively debated since the time of the Spanish arrest warrants against Pinochet. The African disapproval of decisions by European courts to exer

Neglected tropical diseases affect most of the underprivileged populations in tropical countries. Among these are chagas and leishmaniasis, present mainly in South and Central America, Africa and East Asia. Current treatments are long and have severe adverse effects, therefore there is a strong need to develop alternatives. In this study, we base our research on the plant metabolite pulchrol, a na

The raison d’être of the humanities is widely held to reside in its unique ability to generate critical thinking and critical thinkers. But what is “critical thinking?” Is it a generalized mode of reasoning or a form of political critique? How does it relate to discipline-specific practices of scholarly pursuit? How does it relate to discourses of “post-truth” and “alternative facts”? How is it be