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Xyloside analogues with substitution of the endocyclic oxygen atom by sulfur or carbon were investigated as substrates for β-1,4-galactosyltransferase 7 (β4GalT7), a key enzyme in the biosynthesis of glycosaminoglycan chains. The analogues with an endocyclic sulfur atom proved to be excellent substrates for β4GalT7, and were galactosylated approximately fifteen times more efficiently than the corr
What explains variation in military spending? Conventional wisdom suggests that states arm because of either foreign threats or domestic political institutions. The literature treats these factors as distinct and separate (Nordhaus et. al. 2012, Fordham and Walker 2005, Goldsmith 2003). Less attention is given to how states with different internal constraints respond to similar circumstances. This
The environment of the Tibetan Plateau (TP) is regarded as one of the most sensitive ecosystems of the world. However, investigations on effects caused by global climate change or anthropogenic activities are rare due to its quite remote location. This thesis deals with various aspects of the carbon and water cycle within ecological and hydrological studies that can be assessed by measurements of
The arrival of the Digital Age added a new way to preserve memories of war and conflict. These developments beg deeper reflection on the role of cyberspace and how memories of conflict have become publicly and collectively owned, shared and mediated in the digital space. Cyberspace offers a context for the deposit of digital memorials for victims and casualties of war from any adversary in a confl
We present a dual-wavelength polarimetric measurement method to distinguish species and sexes of disease transmitting mosquitoes in flight. By measuring co- and de-polarized backscattered light at 808 and 1550nm, the degree of linear polarization, wingbeat frequency, reflectance, spectral ratio and glossiness of mosquitoes can be retrieved. Body and wing contributions to these signals can be separ
Conodonts have been a key tool for biostratigraphical, evolutionary and palaeobiogeographical studies, and the GermanicBasin has been one of the most important regions for these studies. However, few modern studies provide systematic data onthe mainly endemic conodonts of the Middle Triassic Germanic Basin. Here we document conodonts from two sections inGermany, one Bithynian in age and the other
Våra ögon är viktiga, inte bara för vårt seende, utan också för att synkronisera vår inre biologiska klocka med dygnets 24 timmar. Den biologiska klockan som styr människors dygnsrytm regleras främst av det mönster av ljus och mörker som vi utsätts för under dygnet.Tidigare trodde man att de klassiska fotoreceptorerna, tapparna och stavarna, var de enda ljuskänsliga cellerna i ögat. På 1980-talet
A supervisory observer is a multiple-model architecture, which estimates the parameters and the states of nonlinear systems. It consists of a bank of state observers, where each observer is designed for some nominal parameter values sampled in a known parameter set. A selection criterion is used to select a single observer at each time instant, which provides its state estimate and parameter value
Novel Sm2O3−NiO composite was prepared as the functional electrolyte for the first time. The total electrical conductivity of Sm2O3−NiO is 0.38 S cm−1 in H2/air condition at 550 °C. High performance, e.g. 718 mW cm−2, was achieved using Sm2O3−NiO composite as an electrolyte of solid oxide fuel cells operated at 550 °C. The electrical properties and electrochemical performance are strongly depended
Degrowth scholars and activists have convincingly argued that degrowth in developed nations will need to be part of a global effort to tackle climate change, and to preserve the conditions for future generations’ basic needs satisfaction. However, the barriers to building a broader degrowth movement appear to be very entrenched at present. To improve the political feasibility of degrowth it is imp
Objective: To describe the design and rationale for the genetic analysis of acute and chronic cerebrovascular neuroimaging phenotypes detected on clinical MRI in patients with acute ischemic stroke (AIS) within the scope of the MRI-GENetics Interface Exploration (MRI-GENIE) study. Methods: MRI-GENIE capitalizes on the existing infrastructure of the Stroke Genetics Network (SiGN). In total, 12 inte
A simple and reproducible model for the experimental study of the normally functioning human appendix is described. The appendix removed from a human is transplanted into a nude mouse and is kept vital for at least 4 hours. This model is an improvement on previous models. It corresponds well with the working of the normal human appendix as regards tissue type and characteristics. Results are easil
The power exponent α in the temperature dependence of laminar burning velocity [Formula presented]=[Formula presented]α is usually considered an empirical parameter extracted from measurements performed at different temperatures. In this paper an analytical derivation of α is proposed, calculating the power exponent from the overall activation energy as: αTu 0→Tu
Neurological disorders are among the main clinical problems affecting preterm children and often result in the development of communication and learning disabilities later in life. Several factors are of importance for brain development, however the role of immunoglobulins (passive immunity transfer) has not yet been investigated. Piglets are born agammaglobulinemic, as a result of the lack of tra
Isotopic proveniencing has been applied to human inhumations and cremations as well as fauna from the Viking Age site of Birka and the surrounding Mälaren region, located in east-central Sweden. Human enamel frominhumations has been measured for strontium, oxygen, and carbon isotope ratios (petrous bone from cremations was measured for strontium only) to obtain information on mobility and diet. Se
Reduction of the anticancer trans platinum(IV) prodrug JM335 by thiols in a moderately alkaline aqueous perchlorate medium is quite rapid and yields trans-[Pt(OH)2(c-C6H11NH2)(NH3)] as the reaction product. The mechanism of reduction involves reductive attack by thiol or thiolate on one of the mutually trans chloride ligands, leading to the formation of a chloride-bridged activated complex.The red
