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Background: Nutrition and lifestyle have been long established as risk factors for colorectal cancer (CRC). Modifiable lifestyle behaviours bear potential to minimize long-term CRC risk; however, translation of lifestyle information into individualized CRC risk assessment has not been implemented. Lifestyle-based risk models may aid the identification of high-risk individuals, guide referral to sc
Daylight availability for buildings has been an integral part of architecture since ancient times, yet for the vast majority of countries, criteria for daylight provision were not normative until the 20th century. This article examines the case of Sweden, where the term “daylight” first appeared in regulations in 1960, and assesses the daylight compliance of multi-dwelling buildings before and aft
The use of daratumumab in combination with established regimens for the treatment of newly diagnosed multiple myeloma has recently been authorized by the European Medicines Agency based on results from three separate phase III randomized, active controlled, open-label studies that have confirmed enhanced efficacy and tolerability in both transplant-ineligible (MMY3008 and MMY3007) and transplant-e
Image Processing is rapidly expanding as a technique for object and defect analysis because of the high ease of its coupling to automation and IT solutions. Yet, issues with transferability of the measurement approaches and metrics currently used in mechanical systems often remain unsolved. Study reports on the developed approach for shape and defectiveness characterization by combining Delaunay t
Observational population studies indicate that prevention of dementia and cognitive decline is being accomplished, possibly as an unintended result of better vascular prevention and healthier lifestyles. Population aging in the coming decades requires deliberate efforts to further decrease its prevalence and societal burden. Increasing evidence supports the efficacy of preventive interventions on
Droplets generated by talking and coughing play a major role in the spreading of COVID-19. There is thus a need for accurate measurements of the physical properties of exhaled droplets, including their number, speed and direction.Several challenges are associated with imaging coughed droplets such as high droplet speed near the mouth where both short exposure time to freeze droplet motion and kHz
In this paper, we present an adaptive spectral projection based finite element method to numerically approximate the solution of the wave equation with memory. The adaptivity is not restricted to the mesh (hp-adaptivity), but it is also applied to the size of the computed spectrum (k-adaptivity). The meshes are refined using a residual based error estimator, while the size of the computed spectrum
Despite a long history and the vast number of applications demonstrated, very few market products incorporate acoustophoresis. Because a human operator must run and control a device during an experiment, most devices are limited to proof of concepts. On top of a possible detuning due to temperature changes, the human operator introduces a bias which reduces the reproducibility, performance and rel
Coastal fishing fleets are declining in many parts of Europe. In Sweden, this has left many traditional fishing harbours with no or very few active fishers. This might have effects on the marine tourism industry where the existence of commercial fishing is part of the visitors’ tourism experience. In this paper in-depth interviews with local representatives for the tourism sector are combined with
The European spruce bark beetle (Ips typographus L.) is a major disturbance agent in Norway spruce (Picea abies (L.) Karst) forests in Europe and it is estimated that a changing climate will result in more severe outbreaks in the future. To reduce the risk of large outbreaks it is important to have methods that enable early detection of bark beetle attacks to help forest managers to prevent popula
This paper deals with the estimation of the design force in self-tapping screws used as a reinforcement ofnotched cross laminated timber plates (CLT). With the reinforcement, apart from an increased load-carrying capacity, amore ductile behaviour of this detail can be achieved. An analytical model based on the Timoshenko Beam Theory wasdeveloped, enabling the estimation of the axial force in the r
Background: Patient adherence is defined as the extent to which a patient complies with medical or health advice. At present, there is a lack of reliable and valid measures specifically designed to measure adherence to internet-delivered behavioral interventions. Objective: The objective of this study was to develop and psychometrically evaluate a novel measure of adherence to guided internet-deli
The Sixth Assessment Report (AR6) of the Intergovernmental Panel on Climate Change represents the state of knowledge of anthropogenic disruption to the climate system, its diverse ecosystem and societal impacts, and the imperative for and challenges of mitigation and adaptation responses. It is foundational for global climate policymaking. This paper examines the place of tourism in AR6 and review
This study investigates the use of mobile data to understand patterns of population movements and disease transmission during the Covid-19 outbreak. It also focuses on understanding the implications of using this data for individual privacy. Using a mixed methods approach, we present 10 rich qualitative interviews and 412 survey responses from participants across the Nordics. Our novel results sho
Background & aims: Tissue transglutaminase autoantibodies (tTGA) are used as diagnostic markers of celiac disease. Different methods have been developed for the detection of tTGA of which enzyme-linked immunosorbent assays (ELISA), radiobinding assays (RBA) and electrochemiluminescence (ECL) assays are the most commonly used. Here we aimed to evaluate a novel antibody detection by agglutinatio
It has been proposed that the relatively low duty cycle of the European Spallation Source (ESS) linac allows acceleration of additional mathbfH^- ion pulses interleaved with the baseline proton pulses, representing a unique opportunity to construct a neutrino super beam (ESSnuSB) facility of unparalleled luminosity. Coupled with a distant Cherenkov detector, it is believed that evidence of CP viol
BACKGROUND: Amyloid-β (Aβ) is a normal product of neuronal activity, including that of the aggregation-prone Aβ42 variant that is thought to cause Alzheimer's disease (AD). Much knowledge about AD comes from studies of transgenic rodents expressing mutated human amyloid-β protein precursor (AβPP) to increase Aβ production or the Aβ42/40 ratio. Yet, little is known about the normal expression of Aβ
Mycobacterial infections, including tuberculosis, are a major health problem globally. Prevention and treatments of tuberculosis are challenging due to the poor efficacy of the current vaccine and the emergence of drug-resistant strains. Therefore, it is critical to increase our basic understanding of mycobacterial virulence strategies as well as the host immune response during infection in the co
The role of multiple groups of primary biological aerosol particles (PBAPs) as ice nucleating particles (INPs), and of ice formation processes such as time-dependent freezing of various INPs, and various secondary ice production(SIP) mechanisms in overall ice concentration has been evaluated in a range of cloud systems by simulating them numerically with the state-of-the-art ‘Aerosol-Cloud’ (AC) m
