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In their most extreme form, sex chromosomes exhibit a complete lack of genetic recombination along much of their length in the heterogametic sex. Some recent models explain the evolution of such suppressed recombination by the "sheltering"of deleterious mutations by chromosomal inversions that prevent recombination around a polymorphic locus controlling sex. This sheltering hypothesis is based on
This article examines the narratives associated with the “Shekou Model” in China’s development of the Hambantota International Port in Sri Lanka. Through a dual narrative analysis and policy evaluation approach utilizing official Chinese and Sri Lankan statements, it examines the motivations of the Chinese Communist Party and the China Merchants Group in “selling” the Shekou Model and how Sri Lank
Protein maldigestion and malabsorption lead to malnutrition and are a feature of exocrine pancreatic insufficiency (EPI). Although it is the current standard, measurement of nitrogen in stool to assess protease activity is indirect. Up to 80% of hydrolysed proteins appear in blood in the form of peptides, so we developed a method to measure peptide-derived amino acids in plasma as a relevant measu
The complex orography of the Tibetan plateau (TP) and the scarcity and uneven spatial distribution of meteorological stations present significant challenges in accurately estimating meteorological variables for hydrological simulations. This study aims to enhance the accuracy of daily precipitation and temperature interpolation for hydrological simulations in the Lhasa River Basin (LRB), particula
When processing radar signals, the target steering vector is generally only partially known, being subject to various forms of errors and mismatches. In this article, we investigate the design of an unimodular transmit sequence that is robust against steering vector mismatches, with the aim of enhancing the performance of a frequency diverse array multiple-input-multiple-output (FDA-MIMO) radar sy
Recently, work conducted by the European Commission’s Joint Research Centre demonstrated that Ireland had the highest prevalence of loneliness of all European countries. Given the range of adverse physical and psychological consequences associated with loneliness, it is vital to ask why Ireland is experiencing such high prevalence. Here, we discuss potential contributing factors, including: Irelan
Semiconductor double quantum dots (DQD) coupled to superconducting microwave resonators offer a promising platform for the detection of single microwave photons. In previous works, the photodetection was studied for a monochromatic source of microwave photons. Here, we theoretically analyze the photodetection of single microwave pulses. The photodetection in this case can be seen as a nonlinear fi
Industry 4.0 concepts have recently significantly supported transparency and reliability in every industrial sector. Organizations must adapt their traditional paradigms and approaches to align with market demands. Hence, developing a framework that can change these conventional approaches with fresh ideas is essential. The Industry 4.0 (I4.0) readiness model presents a creative concept that holds
Around midnight of 9 January 1959, the Vega de Tera dam broke, releasing nearly 8 million cubic metres of water that destroyed the Spanish town of Ribadelago, killing 144 people. To this day, it remains the worst dam-related failure of the past two centuries of Spanish history. In this chapter we expand the time frame of the disaster, moving from a one-day narrative to focus on the processes of re
BACKGROUND: Achalasia is a rare motility disorder of the esophagus. The diagnosis involves clinical suspicion based on history details and results of high-resolution manometry (HRM) as recommended by the Chicago classification (CCv4.0). Interpreting data obtained through HRM can be complex especially for the novice user.METHODS: We propose therefore a color-based algorithm involving the "reversed
One of the main challenges as the market for fully commercial electrified vehicles quickly expands is predicting the electromagnetic interference (EMI) in traction voltage systems (TVSs) in differential mode (DM) and common mode (CM). The number of subsystems connected to vehicle TVSs is increasing, and thus, so are the electromagnetic compatibility (EMC) requirements. These requirements should ma
Occupancy is one of the primary contributors to the energy performance gap, defined as the difference between actual and predicted energy usage, in buildings. This paper limits its scope to residential buildings, where occupant-centric consumption often goes unaccounted for in standard energy metrics. This paper starts from the hypothesis that a simple occupant energy efficiency label is needed to
Aim of the review: To provide an overview of studies that have published dataregarding region and population size, procedure location, team composition, inclusionand exclusion criteria, outcome parameters, and cost–benefit analyses onextracorporeal membrane oxygenation use for refractory out-of-hospital cardiac arrest.Data sources: A structured systematic literature search of articles published pr
Diabetes is a growing global problem, with hundreds of millions of people living with the disease worldwide. Diabetes can be divided into two major subtypes, autoimmune type 1 diabetes (T1D), and type 2 diabetes (T2D), which has stronger causal links in obesity, lifestyle, and age. Although immunity and inflammation are clearly defined in T1D, it is also understood that inflammation has a role in
Collective action by small-scale farmers can contribute significantly toward rural development. One important aspect that remains relatively neglected, especially in research set in Africa, is the role of farmer collectives in political processes. We study the local-level dynamics of a farmer-based organization mobilizing for agroecology and food sovereignty in Uganda. Through qualitative, collabo
This chapter builds upon three streams of experience by its author: (a) one related to his six-year term as the first UN Special Rapporteur on human rights and counterterrorism (2005-2011), namely the identification of the absence of a proper international definition of terrorism as an important source of human rights abuses, (b) his observation of actual court practice and media coverage where de
Young adults presenting with knee pain, instability, or both after twisting the knee during sports or at work are commonly seen in primary care. If the symptoms and injury history correspond with suspicion of a torn anterior cruciate ligament (ACL) or meniscal injury, sometimes in combination with positive findings on magnetic resonance imaging, patients are often referred for surgical treatment.
Urban areas provide a promising context for upcycling due to the concentration of consumers and existence of bulky waste resources. Hence, upcycling initiatives emerge across European cities, but little is known about their manifestations. Building on interviews with twenty-four stakeholders from the urban upcycling ecosystem and three focus groups sessions, a morphological model was created with
Major Depressive Disorder (MDD) is a leading global health challenge, affecting nearly 5% of the population. Mounting evidence suggests that systemic low-grade chronic inflammation (SLGCI) plays a central role in the development and progression of MDD. This persistent inflammatory state results from unresolved immune activation and sustained exposure to modern lifestyle factors, such as sedentary
