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With improvements in cancer treatment and supportive care, a growing population of survivors of childhood cancer at risk for significant and potentially life-threatening late effects has been identified. To provide a current snapshot of the models of care from countries with varying levels of resources and health care systems, stakeholders in childhood cancer survivorship clinical care and researc
Uncertainty in pre-industrial natural aerosol emissions is a major component of the overall uncertainty in the radiative forcing of climate. Improved characterisation of natural emissions and their radiative effects can therefore increase the accuracy of global climate model projections. Here we show that revised assumptions about pre-industrial fire activity result in significantly increased aero
Background: Diminished foot somatosensation contributes to balance deficits and increased fall risk. However, it remains unclear if the 256-Hz tuning fork is adequate to measure, in the outpatient clinical setting, somatosensation in relatively healthy elderly. Aims/Objectives: To evaluate the performance of the 256-Hz tuning fork compared to other measures of somatosensation and balance. Material
A purchaser/provider split together with output-based reimbursement were recently introduced by several Swedish county councils. These changes have been motivated by arguments of efficiency and consumer choice. This paper tests the null hypothesis that hospital services are provided as efficiently by county councils with internal markets and output-based reimbursement as by county councils with bu
The dynamics of isolated-photon production in association with a jet in proton–proton collisions at a centre-of-mass energy of 13 TeV are studied with the ATLAS detector at the LHC using a dataset with an integrated luminosity of 3.2 fb−1. Photons are required to have transverse energies above 125 GeV. Jets are identified using the anti-kt algorithm with radius parameter R=0.4 and required to have
The carbon sink potential of peatlands depends on the balance of carbon uptake by plants and microbial decomposition. The rates of both these processes will increase with warming but it remains unclear which will dominate the global peatland response. Here we examine the global relationship between peatland carbon accumulation rates during the last millennium and planetary-scale climate space. A p
A search for a heavy resonance decaying into WZ in the fully leptonic channel (electrons and muons) is performed. It is based on proton–proton collision data collected by the ATLAS experiment at the Large Hadron Collider at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 36.1 fb−1. No significant excess is observed over the Standard Model predictions and limits are
Background: The EsPhALL2004 randomised trial showed a 10% advantage in disease-free survival for short, discontinuous use of imatinib after induction compared with no use of imatinib in patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia receiving Berlin-Frankfurt-Münster chemotherapy and haemopoietic stem-cell transplantation (HSCT). Other contemporary studies showed an a
Direct searches for lepton flavor violation in decays of the Z boson with the ATLAS detector at the LHC are presented. Decays of the Z boson into an electron or muon and a hadronically decaying τ lepton are considered. The searches are based on a data sample of proton-proton collisions collected by the ATLAS detector in 2015 and 2016, corresponding to an integrated luminosity of 36.1 fb-1 at a cen
BACKGROUND: Before this study started, the standard postoperative chemotherapy regimen for stage II-III Wilms' tumour pretreated with chemotherapy was to include doxorubicin. However, avoidance of doxorubicin-related cardiotoxicity effects is important to improve long-term outcomes for childhood cancers that have excellent prognosis. We aimed to assess whether doxorubicin can be omitted safely fro
An experimental test system including the oil circulation system and the gas circuit system has been designed and built to explore the effects of the lubricating oil flow rate on the performance of a single-screw compressor, used in a portable natural gas liquefaction process. Outlet pressure, outlet volumetric flow rate, volumetric efficiency, and specific power rate are the parameters for evalua
This book provides the first comprehensive discussion of conflicts between legal bases in EU law. It fills an important gap in the existing literature on the choice of legal basis in EU law by analysing the structure of legal bases and the resulting legal basis litigation in the European Union, thus identifying areas of conflict produced by overlapping competences, divergent inter-institutional in
Untagged gamma-ray and tagged-neutron yields from 241AmBe and 238PuBe mixed-field sources have been measured. Gamma-ray spectroscopy measurements from 1 to 5 MeV were performed in an open environment using a CeBr3 detector and the same experimental conditions for both sources. The shapes of the distributions are very similar and agree well with previous data. Tagged-neutron measurements from 2 to
Bacterial growth after freezing/thawing was studied in two soils with a history of annual freezing/thawing events. Soil samples were frozen for 1 week at −3 °C or −18 °C, thawed at +4 °C, and respiration and bacterial growth (estimated using leucine incorporation) were compared with reference soils kept at +4 °C. There were no major differences between soils. A respiration pulse, peaking within 9
Can local communities on the margins of society be charged with the responsibility of maintaining their own social order? What type of law (if any) can bring social order to these communities? Using semi-structured interviews with social workers, police officers, lawyers and other professionals familiar with the Tottenham riots, this chapter offers an inside view into what community means in a runCan local communities on the margins of society be charged with the responsibility of maintaining their own social order? What type of law (if any) can bring social order to these communities? Using semi-structured interviews with social workers, police officers, lawyers and other professionals familiar with the Tottenham riots, this chapter offers an inside view into what community means in a run
Fibrinogen can support host antimicrobial containment/clearance mechanisms, yet selected pathogens appear to benefit from host procoagulants to drive bacterial virulence. Here, we explored the hypothesis that host fibrin(ogen), on balance, supports Staphylococcus aureus infection in the context of septicemia. Survival studies following intravenous infection in control and fibrinogen-deficient mice
