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The associations of major foods and fibre with risks of ischaemic and haemorrhagic stroke : A prospective study of 418 329 participants in the EPIC cohort across nine European countries

Aim: To investigate the associations between major foods and dietary fibre with subtypes of stroke in a large prospective cohort. Methods and results: We analysed data on 418 329 men and women from nine European countries, with an average of 12.7 years of follow-up. Diet was assessed using validated country-specific questionnaires which asked about habitual intake over the past year, calibrated us

Attraction modulated by spacing of pheromone components and anti-attractants in a bark beetle and a moth

Orientation for insects in olfactory landscapes with high semiochemical diversity may be a challenging task. The partitioning of odor plumes into filaments that are interspersed with pockets of ‘clean air’ may help filament discrimination and upwind flight to attractive sources in the face of inhibitory signals. We studied the effect of distance between odor sources on trap catches of the beetle,

Molecular evolution of a C5aR antagonist against inflammatory disease

New anti-inflammatory drugs with fewer adverse effects than existing drugs may prove to be useful in the treatment of several inflammatory disorders. A critical step in acute inflammation is the infiltration of neutrophils into tissues. Therefore, molecules that target and inhibit this early inflammatory event are attractive to engineer to suit medical needs. The Chemotaxis Inhibitory Protein of

Engineered Nanoparticles Generation, Characterization and Applications

It is predicted that novel nanometer-sized structures incorporating nanoparticles will have a considerable impact on our lives during the coming decades. Engineered nanoparticles are already found in a number of commercially available products. However, many applications of these nanoparticles have only reached the stage of promising ideas or research demonstrations. The number of nanoparticle-bas

Errors in medication history at hospital admission : Prevalence and predicting factors

Background: An accurate medication list at hospital admission is essential for the evaluation and further treatment of patients. The objective of this study was to describe the frequency, type and predictors of errors in medication history, and to evaluate the extent to which standard care corrects these errors.Methods: A descriptive study was carried out in two medical wards in a Swedish hospital

Developing research priorities for palliative care of people with intellectual disabilities in Europe : a consultation process using nominal group technique

BACKGROUND: Empirical knowledge around palliative care provision and needs of people with intellectual disabilities is extremely limited, as is the availability of research resources, including expertise and funding. This paper describes a consultation process that sought to develop an agenda for research priorities for palliative care of people with intellectual disabilities in Europe.METHODS: A

Aggrecan degradation in human cartilage : Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints

To examine the activity of matrix metalloproteinases (MMPs) and aggrecanase in control and diseased human articular cartilage, metabolic fragments of aggrecan were detected with monospecific antipeptide antibodies. The distribution and quantity of MMP-generated aggrecan G1 fragments terminating in VDIPEN341 were compared with the distribution of aggrecanase-generated G1 fragments terminating in NI

Mutor och moral – motstridiga versioner i svenska rättsfall

High-profile bribery scandals that involve powerful people and large sums of money are often the object of general indignation and legal action. When it comes to bribery of the everyday kind, however, it is far less obvious which gifts should be seen as bribes, be it in a moral or legal sense. Legal cases of this kind almost always include voices that strive to refute accusations of bribery. This

Cerium as a quantum state probe for rare-earth qubits in a crystal

Popular Abstract in Swedish En indikator-jon för en kvantdator Ända sedan transistorn uppfanns 1948 har datorer blivit allt mer kraftfulla. Trots den enorma utveckling som skett finns det fortfarande problem som är för svåra för en dator att lösa. Ett exempel är simulering av stora molekyler, t.ex. proteiner, vilket skulle vara användbart inom medicin och biologi, bland annat för att förutsäga hRare-earth ions doped into a transparent crystal can have optically excited states with coherence times of milliseconds and hyperfine levels with coherence times of hours when cooled down to liquid helium temperatures. This makes them attractive for developing quantum computing hardware. A quantum transistor can be implemented in a rare-earth-ion-doped crystal by utilizing a dipole blockade effe

Ear Reconstruction. Clinical and physiological evaluations.

Popular Abstract in Swedish Mikroti är en medfödd avvikelse där ytterörat inte utvecklats normalt. Defekten kan variera från att örat nästan är normalt till att det saknas helt och hållet, s.k. anoti. I Sverige inträffar detta i c:a 2 fall per 100 000 nyfödda. Pojkar drabbas i större utsträckning och höger sida är den vanligaste. Båda sidor drabbas i c:a en tiondel av fallen. Förträngning av yttreMicrotia is a congenital malformation where the auricle is not fully developed. In some cases the malformation is complete and the auricle is absent. In Sweden the incidence of microtia is about 2 per 10,000 births. Reconstruction of the external ear is possible by using autologous rib cartilage in three surgical steps: rib cartilage transplantation, ear elevation and final adjustments. Although t

Thermochronology of the Talkeetna intraoceanic arc of Alaska: Ar/Ar, U-Th/He, Sm-Nd, and Lu-Hf dating

As one of two well-exposed intraoceanic arcs, the Talkeetna arc of Alaska affords an opportunity to understand processes deep within arcs. This study reports new Lu-Hf and Sm-Nd garnet ages, Ar-40/Ar-39 hornblende, mica and whole-rock ages, and U-Th/He zircon and apatite ages from the Chugach Mountains, Talkeetna Mountains, and Alaska Peninsula, which, in conjunction with existing geochronology, c

Experiences of providing sexual and reproductive healthcare that cannot be deferred – an interview study with healthcare providers

Introduction: Despite Sweden’s commitment to ensure and achieve universal access to sexual and reproductive health (SRH) services, in line with the United Nations’ goals for sustainable development, there is evidence of limited SRH access and outcomes among women with insecure migration status in Sweden. For asylum-seekers and undocumented migrants, access to subsidised SRH services is regulated t

Relevant orsakssamband vid straffbar oaktsamhet inom sjukvården

I uppsatsen behandlas domstolars bedömning av orsakssambandet mellan hälso- och sjukvårdspersonalsstraffrättsliga oaktsamhet och patienters skador eller död. Vårdpersonal är inte undantagna det straffansvar som följer av brottsbalken. Det är dock ovanligt att åtal väcks mot personal inom hälso- och sjukvården och det är ännu mer ovanligt med fällande domar i de fall som prövats av domstol. Detta bThe present study examines the court's evaluation of the causal relationship between the criminal negligence of healthcare professionals and the subsequent injury or death of patients. Healthcare professionals are not exempt from criminal liability under the Criminal Code. However, prosecutions of healthcare professionals are uncommon, and convictions in cases tried by the courts are even rare

Investigating recombinant transaminase stability with cofactor variations and enzyme immobilization

Amine transaminases are valuable biocatalysts in the pharmaceutical industry for the production of chiral amines. Their high regioselectivity and inherent regeneration of cofactor pose them as a greener alternative to the chemical synthesis. However, their application is hampered by their limited stability and narrow substrate scope and product inhibition. Recently, a stable tetrameric amine trans

Chain characterisation of sub-circuits for the study of SRAM

Characterising the performance of ICs is a daunting task. With every year that passes, transistor technology keeps advancing and reducing in size. We are at a moment where, due to working with sub-90nm processes, it is not possible to have complete control over the manufacturing of the chips on the silicon wafers. It is mandatory to characterise the behaviour of each transistor using statistics, n

Physical activity and sedentary behaviour amongst children with obesity - exploring cross-sectional associations between child and parent

Background: Physical activity (PA) in childhood is critical for establishing a healthy lifestyle across the lifespan, particularly to treat and prevent obesity. This study aimed to explore PA and sedentary behaviour (SED) in 6–12-year-old children with obesity and their parents, and possible associations in these behaviours between children and parents. Methods: Children referred to outpatient pae

Measurement report : Eight years of greenhouse gas fluxes at Saclay, France, estimated with the Radon Tracer Method

Here, we use carbon dioxide (CO2), methane (CH4), carbon monoxide (CO), nitrous oxide (N2O) and radon (222Rn) data from the Saclay ICOS tall tower in France to estimate CO2, CH4 and CO fluxes within the station footprint from January 2017 to October 2024 and N2O fluxes from February 2019 to October 2024 using the Radon Tracer Method (RTM). We first performed a sensitivity study of this method appl

Milky Way spiral arms from open clusters in Gaia EDR3

Context. The physical processes driving the formation of Galactic spiral arms are still under debate. Studies using open clusters favour the description of the Milky Way spiral arms as long-lived structures following the classical density wave theory. Current studies comparing the Gaia DR2 field stars kinematic information of the solar neighbourhood to simulations, find a better agreement with sho

Frequency measures obtained from the surface electrocardiogram in atrial fibrillation research and clinical decision-making

Frequency Measures in AF. Introduction: Frequency analysis of fibrillation (FAF) and time-frequency analysis (TFA) were developed recently in order to quantify atrial electrical remodeling in atrial fibrillation (AF) from the surface ECG. This article describes the experience with these two different frequency analysis techniques in consecutive AF patients and discusses possible applications in AF