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Gastroesophageal reflux disease - complications and prognostic aspects

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING Halsbränna och sura uppstötningar är vanliga åkommor i den svenska befolkningen där upp till 20 procent av de tillfrågade uppger sig ha besvär av dessa symtom varje vecka. Både halsbränna och sura uppstötningar anses vara symtom på att magsäcksinnehåll flödar tillbaka upp genom övre magmunnen till matstrupen sk gastroesofageal reflux.This thesis investigates several aspects on gastroesophageal reflux disease (GERD) and associated complications as Barrett’s esophagus and esophageal adenocarcinoma. I. To clarify the natural course of GERD, a pH-metry verified cohort was re-evaluated after 20 years. The course of GERD may well be progressive. A statement based on the evidence that reflux induced complications as esophagitis and

A review of nanowire growth promoted by alloys and non-alloying elements with emphasis on Au-assisted III-V nanowires

Seed particles of elements or compounds which may or may not form alloys are now used extensively in promoting well-controlled nanowire growth. The technology has evolved following the well-known Vapour-Liquid-Solid (VLS) model which was developed over 40 years ago. This model indicates that a liquid alloy is formed from the seed particle and the growth precursor(s), resulting in crystal growth by

Technology, Institutions and Allocation of Time in Urban Swedish Households 1920-1990

The modernisation of Swedish households during the twentieth century prompted a considerable productivity growth in household production. This paper examines the association between this process and the allocation of female time in Swedish urban households during the period 1920-1990. Estimates presented in the paper suggest a minimum potential time reduction for a fixed volume of routine househol

Does a long-term oscillation in nitrogen concentration reflect climate impact on submerged vegetation and vulnerability to state shifts in a shallow lake?

Various ecosystems, including shallow lakes, are suggested to possess alternative stable state dynamics. The response of such systems to environmental change is non-linear and not fully reversible, which calls for identification of feedback mechanisms and subtle changes connected to structural stability. Here, we used a 25-year data series on water chemistry to make inferences on processes prior t

"The sky's the limit": fantasy in the age of market rationality

Purpose - This paper has three purposes. The first is to introduce the concept of fantasy, based on Lacanian pyschoanlysis, in order to link theoretically the role of narrative and affect in organizational strategies of control. The second is to use this concept to illuminate the fantasmatic as well as ideological character of so-called "market rationality." The third is to reveal three dominant f

Demand and Supply of Information on Intangibles: The Case of Knowledge-Intense Companies

This doctoral thesis has its theoretical origin in the notion that the information flow between management teams, financial analysts and investors is especially exposed to information asymmetry when knowledge-intense companies are concerned. Information asymmetry may aggravate agency problems and risk causing an impairment of the efficient allocation of capital on the stock market. Therefore, the

Human Glandular Kallikrein 2

Human glandular kallikrein 2 (hK2) is a serine protease, which is predominantly expressed by the prostate gland and found in seminal plasma at mean levels of 6 mg/ml. It has 79% amino acid sequence identity with prostate-specific antigen (PSA or hK3). The aim of this work was to produce hK2 by recombinant expression technologies in order to study its biochemical and biological properties and its

The order and simplicity of gentrification: a political challenge

As the concept of gentrification celebrates an even forty years, some of the most basic questions about the process itself remain contentious. What is gentrification? What are its root causes? There is surely no lack of answers, though these are largely stamped by disciplined convention. The purpose of this chapter is to revisit these basic questions and formulate answers that facilitate “having g

New Technology-Based Firms in Science Parks - A Study of Resources and Absorptive Capacity

Popular Abstract in Swedish I forskningsparker (Science Parks) finns ett antal resurser tillgängliga för de teknologibaserade företag (NTBF) som valt att lokalisera sig i dessa parker. Om företagen använder dessa resurser kan de också lättare bygga upp den resursbas som företag behöver för att kunna utvecklas och växa. I avhandlingen har tre kategorier av forskningsparksresurser identifierats: UniIn this thesis a strategy perspective (the resource-based view) is applied to the New Technology-Based Firms (NTBFs) in Science Parks, arguing that the Science Park provides the firms with a set of resources that if used could help them build their resource base and thus develop and grow. Three categories of resources are identified in the Science Park; University related resources, Science Park f

Att göra region genom stadspolitik - America's Cup och gränslöshetens gränser

This article is based on a study of the sailing event America’s Cup in Malmö in the late summer of 2005. It serves the purpose of exemplifying a project of urban governance. Urban governance means that municipalities are engaged in implementing different strategies in order to strengthen their own position in the competition between cities and regions. The article’s main theme is the relation betw

Calcification and cellularity in human aortic heart valve tissue determine the differentiation of bone-marrow-derived cells

Human bone-marrow-derived mesenchymal stem cells (MSC) are responsible the remodeling of human tissue. However, damaged aortic valves are lack the ability to regenerate which is an active cell-mediated process. Diseased aortic valve remodeling has similarities even to bone formation. In this study, the prerequisites for cultured MSCs to undergo osteoblastic differentiation on aortic valves were ex

Biomedical and atmospheric applications of optical spectroscopy in scattering media

Popular Abstract in Swedish Den här doktorsavhandlingen handlar om vad som händer när ljus lyser genom spridande material. Det viktigaste användningsområdet är inom medicin, men även tillämpningar inom atmosfärsmätningar berörs. Metoderna som är beskrivs är dessutom så generella att de kan användas för alla typer av spridande material, till exempel olika livsmedel, papper, plast, färg och rök. I eSpectroscopic analysis of scattering media is difficult because the effective path length of the light is non-trivial to predict when photons are scattered many times. The main area of research for such conditions is biological tissues, which scatter light because of variations of the refractive index on the cellular level. In order to analyze tissues to diagnose diseases, or predict doses during,

Low Voltage CMOS Radio Receiver Front-End Design

The mass production of integrated circuits for digital electronics has made CMOS technology the most frequently used IC process today. Thanks to the large production volume, CMOS has increasingly become the most cost efficient technology of choice, and the fast development of small, high speed CMOS devices has made the technology feasible for many RF applications. However, as the transistor featur

Platelet-derived growth factor receptors expressed in response to injury of differentiated vascular smooth muscle in vitro: effects on Ca2+ and growth signals

Vascular smooth muscle cells (VSMCs) in the intact vascular wall are differentiated for contraction, whereas the response to vascular injury involves transition towards a synthetic phenotype, with increased tendency for proliferation. Platelet-derived growth factor (PDGF) is thought to be important for this process. We investigated expression and functional coupling of PDGF receptors (PDGFRs) alph

An electron microscopy study of deformation microstructures in granitic mylonites from southwestern Sweden, with special emphasis on the micas

The lithology, age, geological setting, structural and metamorphic history of the granitic mylonites from the Mylonite Zone (MZ) in southwestern Sweden have been studied extensively. The deformation history, growth of microstructures, intensity of deformation, changes in mineral compositions, and pressure-temperature conditions of deformation have, however, not been addressed. In this study, powde

Phosphatase activity of extra-radical arbuscular mycorrhizal hyphae: A review.

Phosphatase activity of arbuscular mycorrhizal (AM) fungi has attracted attention in three fairly distinct domains: intracellular enzymes with defined metabolic functions that have been studied in intraradical hyphae, histochemical staining of alkaline phosphatase as an indicator of fungal activity measured both intra- and extraradically, and extracellular activity related to mineralization of org

Ice-flow patterns and dispersal of erratics at the southwestern margin of the last Scandinavian Ice Sheet: signature of palaeo-ice streams

An extensive set of proxy-data was acquired from eastern and central Denmark in order to study the dynamic behaviour of the southwestern margin of the last Scandinavian Ice Sheet. We examine the last three glacier advances of the Late Weichselian: the Main advance from central Sweden, representing the maximum ice extent at this time (c. 21-20 ka BP), and the two succeeding Baltic advances (c. 18-1

Vitamin D is related to blood pressure and other cardiovascular risk factors in middle-aged men

A previous study has shown that serum levels of the active vitamin D metabolite 1,25-(OH)2-vitamin D were inversely related to blood pressure levels while the prohormone 25-OH-vitamin D was found to be related to insulin metabolism. Also other clinical and experimental data support the view that vitamin D metabolism is involved in blood pressure regulation and other metabolic processes. The presen

Perceptions of the worker role among people with psychiatric disabilities: Description and investigation of associated factors.

Objective: To investigate how subjective perceptions of everyday occupations, activity level, day centre attendance, social interaction, self-mastery and clinical factors were related to how unemployed people with psychiatric disabilities (PD) envision a future worker role, also controlling for socio-demographic variables. Participants: 175 people with PD; 93 attended a day centre and 82 did not.

"It made me feel human"-a phenomenological study of older patients' experiences of participating in a team meeting

This study focused on older patients participating in a team meeting (TM) in a hospital ward in Sweden. A process had taken place on the ward, in which the traditional round had developed into a TM and understanding what participating in a TM means for the older patient is necessary for the development of care that facilitates older patient's participation. The aim of this study was to describe th