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This cross-sectional study was done in order to ascertain whether there is a lifelong beneficial effect on bone mineral density (BMD) of early, long-lasting, and intense physical exercise. Forty-eight male ex-weight lifters, mean age 64 years (range 50-79) participated. They had followed a training program of an average of 10 hours/week (range 4-20) for an average of 13 years (range 1-34). They ha
Genome-wide association studies have revealed >60 loci associated with type 2 diabetes (T2D), but the underlying causal variants and functional mechanisms remain largely elusive. Although variants in TCF7L2 confer the strongest risk of T2D among common variants by presumed effects on islet function, the molecular mechanisms are not yet well understood. Using RNA-sequencing, we have identified a TC
Background: More than ever, clinicians need regularly updated reviews given the continuously increasing amount of new information regarding innovative cervical cancer prevention methods. Material and methods: A summary is given from recently published meta-analyses on three possible clinical applications of human papillomavirus (HPV)-DNA testing: triage of women with equivocal or low-grade cytolog
The purpose of this study was to investigate the influence of selective denervation of the rat pancreas on hormone secretion and on peripheral insulin sensitivity. Thirteen rats, 7 denervated and 6 sham operated, received an intravenous glucose challenge for 30 min. The basal plasma levels of insulin, glucagon and glucose did not differ between the two groups. An augmented insulin response to gluc
A method for determination of the accessible volume fraction in gels as function of the molecular weight of the solutes is presented. The pore-size distribution is determined by measuring the rate of diffusion of a mixture of solutes into a gel using gel filtration for separation. The solutes, of various sizes, are detected by refractive index measurements. Two marker molecules (blue dextran and g
Particle size distribution (size-range 3-900 nm) and PM10 was measured simultaneously at an urban background station in Copenhagen, a near-city background and a rural location during a period in September-November 2002. The study investigates the contribution from urban versus regional sources of particle number and mass concentration. The total particle number (ToN) and NOx are well correlated at
Nanowires in the InAs/InP material system are grown with catalyst-assisted chemical beam epitaxy. Ohmic contacts are then fabricated to selected wires, allowing electron transport measurements to be carried out at room-temperature as well as at low T. InAs nanowires show strong quantum confinement effects, where thin wires (<30nm) are depleted from carriers. Measurements on InAs wires with a quant
Popular Abstract in Swedish Helicobacter pylori är en Gramnegativ spiralformad human-specifik patogen med förmåga att penetrera magsäckens slemlager och kolonisera i epitelskiktet. H. pylori infektion betraktas som en högriskfaktor för utvecklandet av kronisk gastrit, magsår och ventrikelcancer. H. pylori har en komplex cellyta med ett flertal kolhydratbindande proteiner, sk. lektiner att interageHelicobacter pylori is a gastric pathogen colonising the gastric mucus layer and epithelium of gastric tissue and is associated with chronic type B gastritis and peptic ulcer disease. The attachment of H. pylori to gastric epithelial cells involves several structures recognised by specific bacterial surface proteins. Since colonisation is an initial and critical step in the development of a chroni
Pancreatic cancers are associated with poor survival and only some 10 per cent are resectable, but even in this subgroup recurrence is very frequent. The traditional view of sequential development of pancreatic cancer has been challenged by novel molecular biological findings, where the tumor quite rapidly might turn metastatic. In about 60 000 patients with diagnosed pancreatic cancer the associa
Background: Atrial fibrillation (AF) is a known risk factor for ischemic stroke. Electrocardiographic predictors of AF in population studies such as the Framingham Heart Study, as well as in hypertensive patients have demonstrated a predictive value of the P-wave duration for development of AF. QRS vector magnitude has had a predictive value in ventricular arrhythmia development. We aimed to asses
Inclusive jet production cross-sections are measured in proton-proton collisions at a centre-of-mass energy of s=8 TeV recorded by the ATLAS experiment at the Large Hadron Collider at CERN. The total integrated luminosity of the analysed data set amounts to 20.2 fb−1. Double-differential cross-sections are measured for jets defined by the anti-kt jet clustering algorithm with radius parameters of
Although Singapore, a linguistically and ethnically diverse city–state, uses four official languages, namely Malay, Mandarin, Tamil, and English, which are supposed to enjoy equal status, there appears to be a pecking order to these languages. English seems to be the dominant language when taking into consideration the bilingual education policy, numerous campaigns promoting its use in terms of sp
Background: the European Union of Medical Specialists (UEMS-GMS) recommendations for training in Geriatric Medicine were published in 1993. The practice of Geriatric Medicine has developed considerably since then and it has therefore become necessary to update these recommendations.Methods: under the auspices of the UEMS-GMS, the European Geriatric Medicine Society (EuGMS) and the European Academy
Socioeconomic Inequalities in the KidneyTransplantation Process: A Registry-BasedStudy in SwedenYe Zhang, MSc,1Ulf-G. Gerdtham, PhD,1,2,3Helena Rydell, MD,4,5,6and Johan Jarl, PhD1Background.Few studies have examined the association between individual-level socioeconomic status and access to kidney transplantation. This study aims to investigate the association between predialysis income and educaBackground. Few studies have examined the association between individual-level socioeconomic status and access to kidney transplantation. This study aims to investigate the association between predialysis income and education, and access to (i) the kidney waitlist (first listing), and (ii) kidney transplantation conditional on waitlist placement. Adjustment will be made for a number of medical and
We report on the study of fast-neutron background for the BIFROST spectrometer at ESS. We investigate the effect of background radiation induced by the interaction of fast neutrons from the source with the material of the neutron guide and devise a reasonable fast, thermal/cold neutron shielding solution for the current guide geometry using McStas and MCNPX. We investigate the effectiveness of the
The parameters to extract polysaccharide-enriched fractions (PEF) from mushrooms using MAE (microwave-assisted extraction) were adjusted following a full factorial 3 2 experimental design. The highest yield and total carbohydra
The effect of reaction parameters on lipase-mediated chemo-enzymatic epoxidation of linoleic acid was investigated. Hydrogen peroxide was found to have the most significant effect on the reaction rate and degree of epoxidation. Excess of hydrogen peroxide with respect to the amount of double bonds was necessary in order to yield total conversion within a short time period, as well as at temperatur
Screening for cervical cancer precursors by cytology has been very successful in countries where adequate resources exist to ensure high quality and good coverage of the population at risk. Mortality reductions in excess of 50% have been achieved in many developed countries; however the procedure is generally inefficient and unworkable in many parts of the world where the appropriate infrastructur
