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The cysteine proteases are enzymes found in every kingdom of life. Clan CA is the largest of the cysteine protease clans, with members all displaying a Cys/His/Asn(Asp) catalytic triad responsible for hydrolysing the peptide bond within the substrate. To regulate the activity of the proteases, another group of proteins act as natural inhibitors (cysteine protease inhibitors) and bind to the protea
Förutsägande om klimatförändringar och nederbördsmönster i den närmaste framtiden samt urbanisering leder till högre volymer av avrinning, vilket i sin tur utmanar hållbarheten och funktionaliteten hos stadsdräneringsnät. För att förstå hur dessa förändringar kommer att påverka den befintliga infrastrukturen i stadsområden behövs integrerad programvara för urban vattenmodell för att identifiera efThe predictions on climate change and precipitation patterns in the near future, as well as urbanization, lead to higher volumes of runoff, which in turn challenge the sustainability and functionality of urban drainage pipe networks. In order to understand how these changes will affect the existing infrastructure in urban areas, integrated urban water model software are needed to identify effectiv
Avskiljning, transport och lagring av koldioxid (CCS) är en intressant teknologi med förmågan att minska klimatpåverkande utsläpp inom industrisektorn. Denna teknik framhävs regelbundet på både internationell och nationell nivå som ett nyckelbidrag i kampen mot klimatförändringarna, bland annat förespråkas CCS-teknikens nödvändighet av både EU och IPCC. Användningen av CCS har även uppmärksammats Carbon capture and storage (CCS) is an interesting technology with the ability to reduce carbon dioxide emissions within the industry sector. It is constantly highlighted within the international community as a vital tool in the fight against climate change. Some of those who strongly advocate for the use of CCS include the EU and the IPCC. This technology has also been deemed useful by Swedish au
Background: Over time, methods for the development of clinical decision support (CDS) systems have evolved from interpretable and easy-to-use scoring systems to very complex and non-interpretable mathematical models. In order to accomplish effective decision support, CDS systems should provide information on how the model arrives at a certain decision. To address the issue of incompatibility betwe
Title: Accelerating Service Innovation with Global Account Management – A Case Study at a Manufacturing MNC Author: Emma Malmström – Master of Science in Industrial Engineering and Management, em.malmstrom@gmail.com Tutors: Malin Olander Roese – PhD Researcher, Department of Design Sciences, Faculty of Engineering, Lund University and Susanna Bill – PhD Student, Department of Design Sciences, Fa
For some time, directional antennas have been considered to solve connectivity and interference issues in wireless networks. Several scenarios have been presented and often the conclusions drawn are positive, showing increase in capacity. However, to date there has been no effort to assess a holistic picture of the benefit/cost tradeoff and previous work mainly concerns either link scheduling or a
The 2008–2009 global financial crisis triggered ‘Green Energy Economy’ (GEE) policy packages to stimulate green growth in many countries. China soon became a leader and, supported by its 11th Five-Year Plan (2006–2010), devoted approximately one-third of its US$ 647 billion stimulus package to green energy technologies. Since then, numerous policy instruments have been implemented to encourage ‘Gr
Popular Abstract in Swedish I Big Bang skapades 3 grundämnen: H, He, och spår av Li. Alla andra grundämnen har bildats i stjärnor. Lågmassiva stjärnor som vår sol kan genom kärnreaktioner skapa grundämnen upp till och med syre i det periodiska systemet, medan mer massiva stjärnor kan skapa grundämnen ända upp till järn. Tyngre grundämnen än järn produceras in slutstadierna av stjärnornas liv, tillAll the elements heavier than Li are created during stellar evolution. Even if our knowledge of this process is good, many questions still remain. For instance, the odd-Z iron-peak elements Sc, V, Mn, and Co together with neutron-capture elements Sr, Zr, La, Ce, Nd, Sm, and Eu have still unclear production sites because theoretical models and observational evidences are not in agreement. Having a
Individual monitoring of radiation workers is essential to ensure compliance with legal dose limits and to ensure that doses are As Low As Reasonably Achievable. However, large uncertainties still exist in personal dosimetry and there are issues with compliance and incorrect wearing of dosimeters. The objective of the PODIUM (Personal Online Dosimetry Using Computational Methods) project was to im
Companies are constantly being pressured to innovate in order to stay competitive in the short run and have new offerings in the long run. One way of boosting innovation is to develop idea support systems that go beyond the traditional methods and tools. Through a qualitative study, this paper explores the lessons learned from developing an online platform for idea generation, and discusses it in
Popular Abstract in Swedish Läpp- käk- gomspalt (LKG-spalt) förekommer hos cirka 200 nyfödda barn per år i Sverige. Det finns idag inte belägg för någon specifik faktor som orsakar LKG-spalten. Utan en adekvat habilitering som bl.a. innehåller kirurgi, tandreglering och talbehandling skulle barnen få funktionella och utseendemässiga problem som skulle leda till en försämrad livskvalite. UtvecklinBody dimensions of 2,936 newborns with cleft lip/palate (CLP) were compared with 2,031,140 singleton newborns between 1973 to 1992. The risk of cleft development was found to be associated with intra-uterine growth retardation - the more severe the cleft, the stronger the association. As digital photography is being increasingly applied in clinical medicine, we devised a computer software program
The stochastic behavior of FM-clicks in an unmodulated carrier plus noise is studied in terms of the conditional behavior of stationary Gaussian processes after level crossings. By a systematic use of thc Slepian model processes it is shown that the normalized shape of a positive FM-click approaches a certain rational function with simple random coefficients as the carrier-to-noise ratio tends to
This presentation will give an overview of a peer learning model called Supplemental Instruction - Peer Assisted Study Scheme (SI-PASS). SI-PASS was invented at the University of Missouri in Kansas City, USA in the early1970s and was then directed to Universities and for the university students. In this presentation, the focus and discussion will be on how SI-PASS can be implemented in secondary s
Aim: The aim of this study is to evaluate the quality of data on endometrial (EC) and ovarian, fallopian tube, peritoneal, abdominal or pelvic cancers (OC) registered in the Swedish Quality Register of Gynecologic Cancer (SQRGC). Method: A random sample of 500 patients was identified in the SQRGC and their medical charts were reviewed for re-abstraction of 31 selected core variables by an independ
Background: The effect of interleukin 17-inhibitors on anterior uveitis (AU) in spondyloarthritis (SpA) is poorly understood. This study aimed to compare the risk of AU during treatment with secukinumab versus tumour necrosis factor inhibitors (TNFi). Methods: Patients with SpA starting secukinumab or a TNFi 2015 through 2018 were identified in the Swedish Rheumatology Quality Register. Occurrence
We used eddy-covariance (EC) measurements of net ecosystem exchange (NEE) above canopy to assess the effects of thinning on CO2 fluxes at the ICOS Sweden site Norunda in central Sweden. This forest site consists of mixed pine and spruce stands approx. 100 years old. The thinning during late autumn 2008, performed in a semicircle from the mast extending 200m outwards harvested about 25% of the voluWe used eddy-covariance (EC) measurements of net ecosystem exchange (NEE) above canopy to assess the effects of thinning on CO2 fluxes at the ICOS Sweden site Norunda in central Sweden. This forest site consists of mixed pine and spruce stands approx. 100 years old. The thinning during late autumn 2008, performed in a semi-circle from the mast extending 200 m outwards harvested about 25% of the vo
