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AIMS/HYPOTHESIS: Type 1 diabetes in children is characterised by autoimmune destruction of pancreatic beta cells and the presence of certain risk genotypes. In adults the same situation is often referred to as latent autoimmune diabetes in adults (LADA). We tested whether genetic markers associated with type 1 or type 2 diabetes could help to discriminate between autoimmune and non-autoimmune diab
Popular Abstract in Swedish Förmågan att planera med en medveten mental simulering har ansetts vara unikt mänsklig sedan Aristoteles. När människor planerar för psykologiska eller fysiologiska driftstillstånd som de för närvarande inte upplever, tror man att de använder sig av så kallad episodisk framförhållning. Den episodiska framförhållningen är en del av det större episodiska kognitiva systemeThe ability to plan for future, not currently experienced, mental or physiological states has been regarded as unique to humans. When humans plan for such states it has been hypothesized that they make use of what has been known as episodic foresight. Episodic foresight is a part of the episodic cognitive system, which also includes episodic memory. The defining feature of this system is so-called
Objective: We used dual X-ray absorptiometry (DXA) to measure calcaneal bone mineral density (BMD) and estimate the prevalence of osteoporosis in a population with distal forearm fracture and a normative cohort. Methods: Patients 20 to 80 years of age with distal forearm fracture treated at one emergency hospital during two consecutive years were invited to calcaneal BMD measurement; 270 women (81
Soft tissue sarcomas (STS) represent a group of rare and heterogenous tumors that optimally should be diagnosed and treated within multidisciplinary teams. This thesis has studied various aspects ? pathological, genetical, and clinical ? of STS. In study I, we demonstrated that 20% of the patients in a population-based series of 818 STS developed second primary malignancies. An increased risk of
In a prospective study of a consecutive breast cancer series accumulated in the period 1978-82, the S-phase fraction (SPF) and ploidy status were determined by flow cytometry performed on cell nuclei derived from samples of 580 primary tumors. Sixty percent of the tumors were non-diploid. After correction for debris the median SPF values were 7.3% overall, 12% for non-diploid tumors, and 2.9% for
Background: The maintenance of postural control is fundamental for different types of physical activity. This can be measured by having subjects stand on one leg on a force plate. Many studies assessing standing balance have previously been carried out in patients with ankle ligament injuries but not in patients with ankle fractures. The aim of this study was to evaluate whether patients operated
The study is based on monitoring data on the seasonal variation during four (1996-1999) vegetation periods, as well as long-term summer data on submerged vegetation, nutrients, light, phyto-plankton and zooplankton in Lake Krankesjon, a shallow, calcium-rich, moderately eutrophic take in southern Sweden. The lake has been in the clear water state with abundant submerged vegetation since the end of
Samhället idag kännetecknas av digital interaktion, där både privata såväl som yrkesmässiga kontakter sker via olika tekniska plattformar. Människor skrol-lar, kommunicerar och tar till sig information via mobiltelefoner eller datorer vilket har blivit det normala sättet att interagera i vardagen. Allt fler rättsområ-den har tagit digitaliseringen i beaktning, men det finns fortfarande rättsområ-dSociety today is characterized by digital interaction, with both private and pro-fessional contacts taking place through various technological platforms. Peo-ple browse, communicate and absorb information via mobile phones or com-puters, which has become the normal way of interacting in everyday life. More and more areas of law have taken digitalization into account, but there are still areas of l
Given the current societal and political developments in Germany, the visibility and integration of-marginalized is essential to ensure their inclusion in mainstream society. One way of encouraging-contact between majority and marginalized groups is through building social networks, of which-informal and nonformal educational activities play an important part. This thesis examines the-experience o
Severe conditions and lack of cure for many amyloid diseases make it highly desired to understand the underlying principles of formation of fibrillar aggregates (amyloid). Here, amyloid formation from peptides was studied using Monte Carlo simulations. Systems of 20, 50, 100, 200 or 500 hexapeptides were simulated. Association kinetics were modeled equal for fibrillar and other (inter- and intra-p
Background: The aim of this study was to examine in elderly men a relationship between depressive symptoms, peripheral vascular disease and cerebral blood flow (CBF). Methods: Population-based cohort study started with an examination of 809 men at age 55, followed by the first (age 68ys) and second follow up (age 82ys). 128 survivors were examined at age 82 with Tc-99m-HMPAO-SPECT to estimate CBF,
Background: A number of the deeper divergences in the placental mammal tree are still inconclusively resolved despite extensive phylogenomic analyses. A recent analysis of 200 kbp of protein coding sequences yielded only limited support for the relationships among Laurasiatheria (cow, dog, bat and shrew), probably because the divergences occurred only within a few million years from each other. It
Huvudmålet med miljöbalken är att uppnå en hållbar utveckling. Detta stadgas i balkens portalparagraf och begreppet anses innehålla tre pelare som måste balanseras och tas hänsyn till: ekologisk, ekonomisk och social hållbarhet. För att uppfylla huvudmålet är det viktigt att dess underliggande delmål genomdrivs, varav straff och sanktioner är ett av dessa. Syftet med denna uppsats är att utreda huThe main objective of the Swedish Environmental Code (miljöbalken) is to achieve sustainable development. This objective is stated in the Code’s initial paragraph and the concept contains three pillars which need to be considered and balanced: ecological, economic and social sustainability. To fulfil the main objective an enforcement of its sub targets is important, criminal sanctions being one of
Brottslighet och särskilt organiserad brottslighet, utgör ett problem för samhället i Sverige men också i andra länder. I statsmaktens arbete mot kriminalitet är hindrande av möjligheterna till penningtvätt, ett viktigt inslag. Penningtvättsåtgärder kan nämligen allmänt beskrivas syfta till att dölja eller omsätta vinning av brottslig verksamhet. Studier har visat att omfattande summor pengar frånCrime and in particular organized crime, is a problem for the society in Sweden but also in other countries. Obstruction of opportunities for money laundering is an important element to the authorities in their struggle against crime. Money laundering can generally be described as seeking to conceal or convert the proceeds of criminal activity. Studies have shown that substantial amounts of money
Upphovsrätten utmanas ständigt av nya teknologiska fenomen. På senare tid har den tekniska utvecklingen möjliggjort att alster som tidigare var beroende av mänskligt skapande kan åstadkommas genom mer eller mindre automatiserade processer. I denna kategori finner vi kamerafällor som förenklat kan beskrivas som kameror som antingen ställs in för att ta fotografier konstant eller vid ett visst tidsiCopyright law is constantly challenged by new technological phenomena. Recently, new technology has enabled the making of creations through more or less autonomous processes. Some of these creations were previously dependent on human creativity for its existence. Situated in this category are camera traps. Camera traps can somewhat simplified be explained as cameras that are either set to take pic
Delat ledarskap i den komplexa organisationen - En kvalitativ studie av delat ledarskap utifrån ett kommunikationsperspektiv Denna studie syftar till att med utgångspunkt i strategisk kommunikation analysera delat ledarskap inom en komplex organisation. Genom en fallstudie på Skånes universitetssjukhus har chefers och medarbetares uppfattningar om delat ledarskap studerats för att därmed skapa stShared leadership – A qualitative study of shared leadership from a communication perspective This study aims to examine shared leadership in a complex organization from a strategic communications perspective. Through a case study at Scania University Hospital, managers and co-workers’ opinions about shared leadership are studied in order to receive a better knowledge of shared leadership’s pract
Climate change will alter the hydrological cycle in the 21st century with implications for the water balance and water quality. As characteristics of the landscape may vary significantly between nearby locations, hydrological models need to be able to delineate responses attributed to specific landscape characteristics, to estimate their responses to altered climatic drivers. Small streams are the
