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14-3-3 proteins comprise a family of highly conserved proteins. 14-3-3 proteins have been found in all organisms examined except for members of the prokaryotic kingdom. 14-3-3s are involved in numerous processes in the cell and they typically bind to phosphorylated motifs in other proteins and regulate their activities. In plants, 14-3-3 proteins are recognized as key regulators of primary metabo
Circular building design could significantly reduce the environmental impact of buildings and the pressure on natural resources. However, most buildings today are not designed according to the principles of the circular economy. Most literature has focused on either methods for quantifying the lifecycle analysis of buildings and materials, or on innovative circular building materials, but not muchCircular building design could significantly reduce the environmental impact of buildings and the pressure on natural resources. However, most buildings today are not designed according to the principles of the circular economy. Most literature has focused on either methods for quantifying the lifecycle analysis of buildings and materials, or on innovative circular building materials, but not much
Members of the order Haemosporida are protist parasites that infect mammals, reptiles and birds. This group includes the causal agents of malaria, Plasmodium parasites, the genera Leucocytozoon and Fallisia, as well as the species rich genus Haemoproteus with its two subgenera Haemoproteus and Parahaemoproteus. Some species of Haemoproteus cause severe disease in avian hosts, and these parasites d
We describe a NOVel form of Adaptive softening (NOVA) for collisionless N-body simulations, implemented in the RAMSES adaptive mesh refinement code. In RAMSES - that we refer to as a 'standard N-body method' - cells are only split if they containmore than eight particles (amass refinement criterion). Here, we introduce an additional criterion that the particle distribution within each cell be suff
Objectives: – To quantify the risk of incident psychiatric morbidity after community-acquired sepsis and assess whether new chronic diseases mediate the association. Design: – Nationwide, population-based matched register cohort; hazards estimated with weighted Cox regression. Setting: – Sweden, linking the National Quality Sepsis Registry, National Patient Register, Prescribed Drug Register, and
Sverige blev medlem i den Europeiska unionen 1995. En viktig del i samarbetet är upprättandet av den inre marknaden. EG-fördraget är garanten för att fri rörlighet för varor, tjänster, kapital och personer ska vara möjlig mellan medlemsstaterna. Några hinder för den fria rörligheten får inte förekomma på dessa områden. EG-domstolen ser till att EG-fördragets bestämmelser efterlevs av medlemsstater
Reducing eutrophication in our surface waters caused by nutrient overload is of importance in order to ensure an environment in ecological balance for future generations. Municipal wastewater treatment plants are the main point source of nutrients emissions. Effluent water can be treated by introducing a final advanced treatment step to existing wastewater treatment plants. The present thesis conc
Few-shot segmentation (FSS) tackles data scarcity using multiple priors, but its simplicity limits handling base and novel classes with limited data access. Generalized few-shot semantic segmentation (GFSS) enhances model performance for base classes with abundant data, while novel classes have limited data access, improving generalization with scarce data. Building on the design of query-based se
This paper presents a wideband quadrature radio receiver employing ΔΣ-based A/D-converting channel-select filters (ADCSFs). The output of the quadrature passive mixer is directly connected to the input of the ADCSFs, where a first-order ΔΣ modulator is incorporated into a fourth-order Butterworth channel-select filter (CSF) to provide sufficient dynamic range for a cellular system. A design method
In the era of Internet of Things, software systems need to interact with many physical entities and cope with new requirements at runtime. Self-Adaptive systems aim to tackle those challenges, often representing their context with a runtime model enabling better reasoning capabilities. However, those models quickly grow in size and need to be updated frequently with small changes due to a high num
Somatic rearrangements contribute to the mutagenized landscape of cancer genomes. Here, we systematically interrogated rearrangements in 560 breast cancers by using a piecewise constant fitting approach. We identified 33 hotspots of large (>100 kb) tandem duplications, a mutational signature associated with homologous-recombination-repair deficiency. Notably, these tandem-duplication hotspots were
The Historical Varieties of Democracy dataset (Historical V-Dem) contains about 260 indicators, both factual and evaluative, describing various aspects of political regimes and state institutions. The dataset covers 91 polities globally – including most large, sovereign states, as well as some semi-sovereign entities and large colonies – from 1789 to 1920 for many cases. The majority of the indica
The research aims to language analysis of the Arab critical speech, which dealt with the study of narrative, in the theoretical and practical side, using pragmatic mechanisms, including holdings of terms, and effective tools in linguistic studies. It’s the starting point for many of the process of modern literary criticism. The study has taken two ways: first, the side of theoretical through summ
Sensitivity analysis consists of an integral and important validatory check of a computer simulation model before the code is used in performing any kind of analysis operation. The present paper demonstrates the use of a relatively new method and tool for conducting global sensitivity analysis (GSA) for environmental models, providing simultaneously the first GSA study of the widely used 1d soil-v
BACKGROUND: Triage is widely used in the emergency department (ED) in order to identify the patient's level of urgency and often based on the patient's chief complaint and vital signs. Age has been shown to be independently associated with short term mortality following an ED visit. However, the most commonly used ED triage tools do not include age as an independent core variable. The aim of this
Background: Persons with clinical onset of Alzheimer’s disease (AD) before 65 years of age are diagnosed with early-onset AD (EOAD). The prevalence of EOAD is low, but varies among studies from 6% to 16%. Most individuals with EOAD are still working, have an active social life, and might have children living at home. Therefore, the consequences of being diagnosed early with a disease that implies
Popular Abstract in Swedish Syftet med avhandlingen är att undersöka bondeskapets (the peasantry)framtida existens. Analysen görs på global nivå, men framför allt på lokal nivå i samband med implikationerna av Mexikos nya jordreform från 1992. Bonden dekonstrueras i ekonomisk-och sociopolitisk aktör för att belysa hans/hennes complexitet. Försörjningsstrategier i tider då staten ersätts av markandThe thesis deals with a classical issue, that of the fate of the peasantry, in particular the process of the transformation of the peasantry. The aim is to explore whether there is a place for the smallholding peasantry in the future, or if the process of dissolution is inevitable. The discussion of this broad question is approached by first deconstructing the peasantry into economic actors and so
We report on the study of six similar buildings built in an area of Gothenburg, Sweden, in 1971, which are now in urgent need of renovation. However, the owner of the buildings - a municipal housing company did not achieve a financially viable renovation of the pilot project. This meant that renovation on a similar basis for the remaining five buildings would not be possible. For this reason the h
