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Type-2 diabetes (T2D) develops due to insulin resistance and an inability of the pancreatic β-cells to increase secretion of insulin and reduce elevated blood glucose levels. Diminished β-cell function and mass have been implicated in impaired β-cell secretory capacity and several microRNAs (miRNAs) have been reported to be involved in regulating β-cell processes. We believe miRNAs are nodes in im
Aim: Understanding how climate conditions influence plant–pollinator interactions at the global scale is crucial to understand how pollinator communities and ecosystem function respond to environmental change. Here, we investigate whether climate drives differences in network roles of the main insect pollinator orders: Diptera, Coleoptera, Lepidoptera and Hymenoptera. Location: Global. Time period
Large amounts of germline sequencing data have recently become available and we sought to compare these results with population-based family history data. Family studies are able to describe aggregation of any defined cancers in families. The Swedish Family-Cancer Database is the largest of its kind in the world, covering the Swedish families through nearly a century with all cancers in family mem
Background: Preventing and responding to gender-based violence (GBV) is both a human rights imperative and a multifaceted economic issue. GBV can also act as a barrier to economic empowerment. The aim of the study was to examine the association between women’s empowerment (physical mobility, decision making and economic resources) and GBV among married youth in India. Methods: Community based cros
Purpose: Caveolin-1 (CAV1) has been implicated in breast cancer oncogenesis and metastasis and may be a potential prognosticator, especially for non-distant events. CAV1 functions as a master regulator of membrane transport and cell signaling. Several CAV1 SNPs have been linked to multiple cancers, but the prognostic impact of CAV1 SNPs in breast cancer remains unclear. Here, we investigated CAV1
Introduction: Proton radiation therapy (PT) has become a treatment option alongside photon therapy (XRT) for lower-grade gliomas (LGG). In this single-institution retrospective study, we investigate the patient characteristics and treatment outcomes, including pseudo-progression (PsP), for LGG patients selected for PT. Method: Adult patients with grade 2–3 glioma consecutively treated with radioth
Background: Optimizing rectal suction biopsy (RSB) diagnostics in Hirschsprung’s disease (HD) may shorten diagnostic time and prevent need for repeated biopsies. Aim: To explore whether systematic orientation of fresh RSB specimens increased biopsy quality, diagnostic times, diagnostic efficacy, and histopathologic workload, and to explore these outcome measures for aganglionic specimens. Material
Due to global demand for alternative energy sources, the industry of hydropower is continuing to thrive. Not only are there already thousands of dams worldwide, but many more developments are planned for the future. This has increased attention towards the topic of reservoirs, and more specifically their potential to act as a source of greenhouse gases. Despite tropical locations being known as ‘h
Purpose: The aim of this paper is to find out how the PMM system can be used to remain resilient to a change in the environment and so continue to provide appropriate guidance to managers in real time. Methodology: The paper is based on a qualitative research method with primarily an abductive approach to derive insight about a PMM system’s use to remain resilient to a change in the environment.
Recently, several regions in southern Sweden suffered extremely low groundwater levels following a long-term infrequency in rainfall. In response, irrigation was banned in many of the affected municipalities during 2016–2017, amongst which Mörbylånga municipality was one. Because nearly half of the nation’s drinking water is extracted from groundwater, protecting and managing this vital resource i
Although landscape representations in the US-European culture have traditionally been acknowledged as a peaceful ordering of the world or the tool of imperialism, nationalism and private property (sometimes all simultaneously), a new shift in the landscape scopic regime seems to be happening. Produced by the current rise of concerns around climate change and environmental crisis, this shift seems
Today sharing data is done everywhere. Doctors might want to share patient journal information. Patient journals may contain sensitive information that doctors do not want to share. The journals needs to be checked before they are shared. In this thesis, data and journals are coded in XML and checking journals and data is the same as validating XML. Validating XML documents is usually done by foll
The increased competition for talented employees is a new challenge for todays organizations to reach success and as a response to this challenge the term Talent Management was developed during the 1990s. Due to the relatively new concept there is still no generally accepted definition and the purpose of this study is to contribute with knowledge about what defines Talent Management and how it has
Landfill gas, consisting mainly of methane and carbon dioxides, is produced on waste disposal sites which contain organic waste. The release of the gas to the environment gives rise to several environmental effects. Regulation in Sweden requires that the landfill gas is managed in some way, for example to reduce emissions. The management options are energy utilization or flaring. In a situation wi
Forskningsfråga: Hur implementerar fastighetsutvecklingsbolaget Granitor Properties cirkularitet i sin ekonomistyrning, och vilka svårigheter och möjligheter kan identifieras? Syfte: Syftet med uppsatsen är att undersöka hur ett företag inom fastighetsutvecklingsbranschen implementerar cirkularitet i sin ekonomistyrning för att få en förståelse för hur detta fungerar i praktiken. Arbetet syftar ä
Det svenska vägnätet är uppdelat i allmänna vägar, kommunala gator och enskilda vägar. De allmänna vägarna sköts generellt av staten via Trafikverket. Ansvaret kan emellertid, om regeringen lämnat ett förordnande om det, överlämnas till den berörda kommunen. Förordnandet kan gälla för ett helt område, eller enskilda vägar. Kommunen är väghållare för de kommunala gatorna inom detaljplan med kommunaA municipality in Sweden has two different choices regarding how to plan and build transportational infrastructure such as roads. The most used way is to use the planning and building act and establish a detailed development plan, but the municipality could also establish a road plan according to the road act. This paper examines the connection between the two laws and how those apply on the munic
Today, more and more consumers are asking brands to take a stand on socio-political issues in order to generate a values-based connection with consumers. However, most previous research has focused only on individual brand activism, with little attention paid to co-branding brand activism. Through the co-branding case of Dove and The Body Shop, this study aims to understand how Dove framed its col
The subject of this thesis is derived from the scientific problem of the encounter between history and politics. The aim is to analyse the Sweden Democrats' use of history which manifests itself in their political rhetoric. Specifically, the importance of their interest in history in their struggle to attain dominance over the interpretation and arrangement of Swedish history as a whole. My pr
Climate change, the energy crisis of 2022-2023, and estimations of future electricity demands have stressed the necessity for a rapid transition of the energy system. Offshore wind energy plays an important role in this transition, and is expected to expand considerably on a global level, in the EU and in Sweden. While Swedes show high support of wind energy, a majority of recent projects have bee
