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TFAP2B influences the effect of dietary fat on weight loss under energy restriction

Background: Numerous gene loci are related to single measures of body weight and shape. We investigated if 55 SNPs previously associated with BMI or waist measures, modify the effects of fat intake on weight loss and waist reduction under energy restriction. Methods and Findings: Randomized controlled trial of 771 obese adults. (Registration: ISRCTN25867281.) One SNP was selected for replication i

On exposure to anorexia nervosa, the temporal variation in axial and appendicular skeletal development predisposes to site-specific deficits in bone size and density : A cross-sectional study

Skeletal development is heterogeneous. Throughout growth, bone size is more maturationally advanced than the mineral being accrued within its periosteal envelope; before puberty, appendicular growth is more rapid than axial growth; during puberty, appendicular growth slows and axial growth accelerates. We studied women with differing age of onset of anorexia nervosa to determine whether this tempo

Coping facilitated troponin T increases and hypo-responsivity in the copeptin-HPA-axis during acute mental stress in a Black cohort : The SABPA study

BACKGROUND: Defensive coping (DefS) was associated with a vulnerable cardiovascular profile in Blacks. The copeptin/vasopressin system is a manifestation of hypothalamic-pituitary-adrenal-axis activity and may act as an acute compensatory mechanism when there is a disruption in volume-loading homeostasis, i.e. when cardiac stress is evident. Whether DefS will influence associations between copepti

Salvage radiotherapy after radical prostatectomy : functional outcomes in the LAPPRO trial after 8-year follow-up

OBJECTIVE: Radical prostatectomy reduces mortality among patients with localized prostate cancer, however up to 35% of patients will experience biochemical recurrence, often treated with salvage radiotherapy. The objective of the study was to investigate long-term effects of salvage radiotherapy. METHODS: A prospective, controlled, non-randomized trial at 14 Swedish center's including 4,003 patien

False-positive recalls in the prospective Malmö Breast Tomosynthesis Screening Trial

Objectives: To evaluate the total number of false-positive recalls, including radiographic appearances and false-positive biopsies, in the Malmö Breast Tomosynthesis Screening Trial (MBTST). Methods: The prospective, population-based MBTST, with 14,848 participating women, was designed to compare one-view digital breast tomosynthesis (DBT) to two-view digital mammography (DM) in breast cancer scre

Association between obstructive sleep apnoea and cancer : a cross-sectional, population-based study of the DISCOVERY cohort

Objectives Nocturnal hypoxia in obstructive sleep apnoea (OSA) is a potential risk factor for cancer. We aimed to investigate the association between OSA measures and cancer prevalence in a large national patient cohort. Design Cross-sectional study. Settings 44 sleep centres in Sweden. Participants 62 811 patients from the Swedish registry for positive airway pressure (PAP) treatment in OSA, link

Efficacy and cost-effectiveness of therapist-guided internet-delivered behaviour therapy for children and adolescents with Tourette syndrome : study protocol for a single-blind randomised controlled trial

Background: Treatment guidelines recommend behaviour therapy (BT) for patients with Tourette syndrome (TS) and chronic tic disorder (CTD). However, BT is rarely accessible due to limited availability of trained therapists and long travel distances to specialist clinics. Internet-delivered BT has the potential of overcoming these barriers through remote delivery of treatment with minimal therapist

Long-term outcomes of vedolizumab in inflammatory bowel disease : the Swedish prospective multicentre SVEAH extension study

Background: Real-world data on long-term outcomes of vedolizumab (VDZ) are scarce. Objective: To assess long-term outcomes (up to 3 years) of VDZ in treating inflammatory bowel disease (IBD). Design: A nationwide, prospective multicentre extension of a Swedish observational study on VDZ assessing Effectiveness And Healthcare resource utilization in patients with IBD (SVEAH). Methods: After re-cons

Detection of oncogenic viruses SV40, BKV, JCV, HCMV, HPV and p53 codon 72 polymorphism in lung carcinoma

As a part of our continuous search for oncogenic viruses in bronchial cancer, we extended our HPV studies to analyse also SV40, BKV, JCV and HCMV sequences in bronchial cancer and related these data with p53 codon 72 polymorphism. Fresh tumor samples from 78 patients with lung cancer were analysed for SV40, BKV, JCV, HCMV and HPV sequences by PCR. HPV genotypes were determined using reverse blot h

Periradicular surgery : A longitudinal registry study of 10-year outcomes and factors predictive of post-surgical extraction

Aim: This historical prospective cohort study of the adult population of Sweden is based on data from a national registry: the primary aim was to evaluate the long-term survival of teeth after periradicular surgery. A secondary aim was to identify factors predictive of extraction within 10 years of registration of periradicular surgery. Methodology: The cohort consisted of all individuals who had

Prospective Attitudes towards Respiratory Syncytial Virus (RSV) Vaccination : Validation of a Survey Instrument among Young Females in Jordan Pending Vaccine Authorization

In May 2023, the U.S. FDA advisors endorsed Pfizer’s pregnancy-administered vaccine (branded ABRYSVO) to protect infants from respiratory syncytial virus (RSV) infection. Vaccination can reduce the burden of RSV-related respiratory disease, with previous studies showing its substantial medical and financial burden in Jordan. However, pregnant women may exhibit hesitancy to get vaccinated due to co

Geocoded Population at Address and Block Level: Landskrona, 1904-1967, Machine-readable database, Version 1

This dataset features geocoding for the complete population of:Landskrona at the block-level from 1904-1967;Landskrona at the address-level from 1939-1967; andKävlinge at the block-level from 1939-1967.All these populations are part of the Scanian Economic-Demographic Database (SEDD). SEDD is a high-quality, longitudinal database that covers five Scanian parishes: Halmstad, Hög, Kågeröd, Kävlinge,

Agreement between self-reported and objectively assessed physical activity among out-of-hospital cardiac arrest survivors

BACKGROUND: Low level of physical activity is a risk factor for new cardiac events in out-of-hospital cardiac arrest (OHCA) survivors. Physical activity can be assessed by self-reporting or objectively by accelerometery.AIM: To investigate the agreement between self-reported and objectively assessed physical activity among OHCA survivors HYPOTHESIS: Self-reported levels of physical activity will s

Changes in joint cartilage aggrecan after knee injury and in osteoarthritis

Objective. To determine the concentrations of aggrecan fragments in synovial fluid from patients with knee joint injury, osteoarthritis (OA), or acute pyrophosphate arthritis (PPA; pseudogout), and to test their relative reactivity with the 846 epitope, a putative marker of cartilage aggrecan synthesis. Methods. Samples of knee joint fluid from 385 patients and 9 healthy-knee volunteers were obtai

Kardiovaskulära händelser i MKC

MDC Cardiovascular endpoint report 2017 Malmö Diet and Cancer Studyincl. CV-cohortCardiovascular EndpointsEnd of follow-up: 31 December 2016Report: 4 April 2018By Anders Dahlin (data manager)Bo Hedblad (coronary events and stroke)Gunnar Engström (heart failure)Olle Melander (atrial fibrillation and flutter)Gustav Smith (CABG, PCI, MACE, aortic stenosis) General informationAll cardiovascular diseas

https://www.malmo-kohorter.lu.se/malmo-kost-cancer-mkc/mkc-uppfoljning/kardiovaskulara-handelser-i-mkc - 2026-06-07

Litteraturlista: Klimatförändringen, vetenskap och samhälle (MVEN15) höstterminen 2024

KursansvarigNiklas Varemanniklas [dot] vareman [at] med [dot] lu [dot] seKursbok Houghton, J. 2015. ”Global warming, the complete briefing”, femte upplagan, Cambridge University Press.  Finns som e-bok på UB: https://www-cambridge-org.ludwig.lub.lu.se/highereducation/books/global-warming/C1706360E0FEC4F43D47392D8F9EECF0#contents Övrig litteraturlista - delar av vilken kan förekomma på framför allt

https://www.cec.lu.se/sv/litteraturlista-klimatforandringen-vetenskap-och-samhalle-mven15-hostterminen-2024-0 - 2026-06-07

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HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 45, 2019/20, Nr 7, 2020-02-25 DISPUTATIONER Avhandlingar från andra institutioner står på en hylla i korridoren på plan 3. Du är välkommen att bläddra i dem, men de ska ställas tillbaka genast, inte tas med till rummet för läsning. Vi saknar ett par avhandlingar. Ett exemplar lämnas alltid till biblioteket och kan alltså lånas där. Lund Fr

https://www.hist.lu.se/fileadmin/user_upload/historiska/hist/hilma/HILMA_2020-02-25.pdf - 2026-06-06

Feature – Sida 35 – Vetenskap och Hälsa

Feature – Sida 35 – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Kategori: Feature Försök med genterapi vid ärftliga ögonsjukdomar 2010-09-29 Forskare vid Lunds universitet har visat att genterapi kan fungera vid vissa ärftliga sjukdomar på ögats näthinna. Professor Sten Andréasson vid av

https://www.vetenskaphalsa.se/kategori/feature/page/35/ - 2026-06-07