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Familial risks for cancer are important for clinical counseling and understanding cancer etiology. Medically verified data on familial risks have not been available for all types of cancer. The nationwide Swedish Family-Cancer Database includes all Swedes born in 1932 and later (0-to 68-year-old offspring) with their parents, totaling over 10.2 million individuals. Cancer cases were retrieved from
Objectives: Rituximab (RTX) is an anti-CD20 antibody that selectively depletes B cells and has emerged as a therapy for ANCA-associated vasculitis (AAV) during the past decade. This study sought to quantify and determine potential risk factors for severe infections in AAV patients treated with RTX at rheumatology clinics in Mexico City, Mexico and Lund, Sweden. Methods: The study consisted of a re
BACKGROUND: The elapsed time taken to diagnose tumors of the central nervous system in children and adolescents varies widely. The aim of the present study was to investigate such diagnostic time intervals at a national level in Sweden as they correlate with clinical features.METHODS: Data prospectively accumulated over a 4-year period in the Swedish Childhood Cancer Registry from patients aged 0-
Previous studies have identified an association between osteoporotic fracture and a polymorphism affecting a Sp1 binding site in the first intron of the collagen type I alpha 1 gene (COL1A1). It is currently unclear, however, whether this association is direct or the result of linkage disequilibrium with other polymorphisms situated nearby. In this study we analyzed the relationship between four w
Objectives: To use a population pharmacokinetic approach to define maximally effective meropenem dosing recommendations for treatment of Acinetobacter baumannii and Pseudomonas aeruginosa infections in a large cohort of patients with septic shock. Methods: Adult patients with septic shock and conserved renal function, treated with meropenem, were eligible for inclusion. Seven blood samples were co
Permafrost regions contain approximately half of the carbon stored in land ecosystems and have warmed at least twice as much as any other biome. This warming has influenced vegetation activity, leading to changes in plant composition, physiology, and biomass storage in aboveground and belowground components, ultimately impacting ecosystem carbon balance. Yet, little is known about the causes and m
Background and purpose — At our institution, new-borns with Barlow or Ortolani positive hips have been treated for 12 weeks with the von Rosen abduction splint until 2012 when the treatment length was halved. We inves-tigate whether acetabular development at 12 months of age and complications differ between hips treated with the von Rosen splint for 6 compared with 12 weeks. Patients and methods —
Objectives: In radiotherapy, delineation uncertainties are important as they contribute to systematic errors and can lead to geographical miss of the target. For margin computation, standard deviations (SDs) of all uncertainties must be included as SDs. The aim of this study was to quantify the interobserver delineation variation for stereotactic body radiotherapy (SBRT) of peripheral lung tumours
The amyloid precursor protein intracellular domain (AICD) is an intrinsically disordered regulatory segment whose conserved YENPTY motif mediates transient interactions with multiple adaptor and signaling proteins. How sequence perturbations within this motif modulate its accessibility and interaction potential within a disordered ensemble remains poorly understood. Here, we combine small-angle X-
Background: Effectively identifying individuals exposed to drug underuse, overuse and potentially inappropriate medication (PIM) in older adults is essential for minimizing preventable drug-related harms. Methods: We analysed data from 54,296 individuals aged 60–74 years from the German National Cohort (NAKO). We assessed the frequency of PIM, untreated conditions (medication and vaccination under
Background Anti-interleukin (IL)-4Rα monoclonal antibodies (mAb) improve lung function and decreasethe number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement ofearly innate immune responses underlying these treatment effects is not well known. We sought tounderstand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells (BECs) fromCBackgroundAnti-IL-4Rα monoclonal antibodies (mAb) improve lung function and decrease the number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement of early innate immune responses underlying these treatment effects is not well known. We sought to understand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells from COPD patients under
Recent years have seen a rise in extreme heat event (EHE)-related deaths in India. However, the impact of specific temperature thresholds on health risks remains understudied. Using Distributed Lag Non-Linear Models (DLNM), we explored the link between EHEs, defined by various temperature thresholds, and mortality risk in Ahmedabad, India, from 2002 to 2018, considering a 21-day lag. We observed a
Bi-lagan 030216 korrigerad 030331 nätversion.indd Nationellt resurscentrum för biologi och bioteknik • Bi-lagan nr 1 2003• Får fritt kopieras om källan anges.2 3Nationellt resurscentrum för biologi och bioteknik • Bi-lagan nr 1 2003• Får fritt kopieras om källan anges. Uttalandet är Linnés och sätter fi ngret på en viktig sak – nämligen behovet av artkunskap för att underlätta förståelsen av natur
https://www.botan.lu.se/sites/botan.lu.se/files/lar_med_knoppen_0.pdf - 2026-07-05
Lending conditions LUND UNIVERSITY LIBRARIES Lending conditions in brief • Loans can be made to persons with a Swedish personal identity number or coordination number, who are over 18 years of age. • Guest students or –researchers must show a letter of acceptance or certificate of affiliation, to get a library card at Lund University Libraries. • You must always be prepared to show your library ca
https://www.lub.lu.se/en/sites/lub.lu.se.en/files/2021-03/L%C3%A5nevillkor%202021%20eng%20webb.pdf - 2026-07-05
Centre for Economic Demography Lund University School of Economics and Management P.O. Box 7080 SE-220 07 Lund, Sweden www.ed.lu/publications/Lund-Papers-in-Economic-Demography/ Ethnic Composition of Couples and Mutual Health Benefit Receipt: Register-Based Evidence from Finland JAN SAARELA, MARIA STANFORS, MIKAEL ROSTILA LUND PAPERS IN ECONOMIC DEMOGRAPHY 2021:3 http://www.ed.lu/publications/Lund
https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-07/LPED_2021_3.pdf - 2026-07-05
Brevmall Postadress Paradisgatan 5 Telefon dir 046-222 91 21, växel 046-222 00 00, E-post Anita.Lennerstedt@psy.lu.se Internet http://www.psy.lu.se Ins t i tu t ionen för psykologi Ledningsgruppen för psyko logprogrammet Närvarande ledamöter Martin Wolgast Ordförande Inst för psykologi Kristian Almquist Studievägledare ”- Bengt Brattgård Lärarlag kurs 10 ”- t o m § 4 c, § 4 e Kati Bergman Lärarlag
https://www.psy.lu.se/sites/psy.lu.se/files/psp_160914_nr5_protokoll.pdf - 2026-07-05
MVEN17 Samhällsplanering med klimatperspektiv Kurstid: 18 jan-21 mars 2016 Kursansv: Carl Dalhammar carl.dalhammar@iiiee.lu.se MVEN05 Johanna Alkan Olsson johanna.alkan_olsson@cec.lu.se MVEN17 Lärare LU: Jonas Sonnenschein jonas.sonnenschein@iiiee.lu.se Andrius Plepys andrius.plepys@iiiee.lu.se Jasmine Livingston jasmine.livingstone@cec.lu.se Terese Göransson terese.goransson@cec.lu.se Maria Johan
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mven17_vt16_webb_v3.pdf - 2026-07-05
Representing Sustainability 7.5 credits Spring 2023 This doctoral course will examine how narratives around the global goals are created, can be understood and also how it relates to the doctoral student's own research. The doctoral students will gain a theoretical and practical foundation in discourse analysis and metaphor analysis in order to critically review the language, images and narratives
