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Patients with diabetes display a progressive decay in the physiological counter-regulatory response to hypoglycemia, resulting in hypoglycemia unawareness. The mechanism through which the brain adapts to hypoglycemia may involve brain glycogen. We tested the hypothesis that brain glycogen supercompensation following hypoglycemia depends on blood glucose levels during recovery. Conscious rats were
Spatial and temporal patterns of trends in annual and seasonal precipitation over Germany during 1951–2013 were analysed using the ensemble empirical mode decomposition (EEMD) method. Three widely used and recognized high-resolution observation-based gridded precipitation products, the Climatic Research Unit (CRU) time-series data, Global Precipitation Climatology Centre (GPCC) Full Data Reanalysi
BACKGROUND: It is discussed whether fetal scalp stimulation (FSS) test is a reliable complimentary tool to cardiotocography (CTG) to assess fetal wellbeing during labor. The test is based on the assumption that a well-oxygenated fetus, in contrast to the depressed fetus, will respond to a certain stimulus. The aim of this study was to investigate the effectiveness of the FSS-test.METHODS: A retros
CONTEXT: Whether multisystem morbidity in Cushing's disease (CD) remains elevated during long-term remission is still undetermined. OBJECTIVE: To investigate comorbidities in patients with CD. DESIGN, SETTING, AND PATIENTS: A retrospective, nationwide study of patients with CD identified in the Swedish National Patient Register between 1987 and 2013. Individual medical records were reviewed to ver
We have reconstructed the distribution of extraterrestrial chrome spinels in a marine limestone section across the Frasnian–Famennian stratotype section at Coumiac in southern France, providing the first insights on the types of micrometeorites and meteorites that fell on Earth at this time. The data can test whether the small cluster of roughly coeval, large impact structures is related to an ast
Phase separation of dough is based on the thermodynamic incompatibility of its components. The studies on phase-separated systems allow to model, understand, and develop foods. Model dough systems made with water and wheat flour were disassembled into their main structural phases, i.e. liquid, gel, gluten and starch phases, by ultracentrifugation, and further characterized with differential scanni
Qualitative and quantitative changes were observed in lipids, poly-β-hydroxybutyrate (PHB), and a cell wall peptidoglycan consitutent in a marine bacterial isolate during starvation for 24 h in an energy and nutrient-free medium. While the amount and composition of the membrane fatty acids fluctuated within the first hours of starvation, the total amount of fatty acids decreased during the starvat
The high variability in the hydrological regime of the Eastern Hydrological Region (EHR) of Northeast Brazil often results in floods and droughts, leading to serious socio-economic issues. Therefore, this work aimed to investigate connections between spatiotemporal hydrological variability of the EHR and large-scale climate phenomena. Multivariate statistical techniques were applied to relate clim
BackgroundMany countries and regions undergo structural changes that intent to improve the effectiveness and quality of care. Until 2007, the municipalities, counties, hospitals and pharmacies shared the smoking cessation activities almost equally in Denmark. Among others, the Danish Healthcare Reform 2007 intended to add responsibility for smoking cessation intervention at county level to the mu
This study aims to reveal the obstacles to achieving quality in distance learning during the Coronavirus (COVID-19) pandemic and was based on a large sample of professors and students of universities in the Arab world (Algerian, Egyptian, Palestinian, and Iraqi). The primary aim of this research was to investigate the various ways in which students pursued their studies at home during the universi
Changing acceleration and forces are part of the excitement of a roller coaster ride. According to Newton's second law, F = ma, every part of our body must be exposed to a force to accelerate. Since our bodies are not symmetric, the direction of the force matters, and must be accounted for by ride designers. An additional complication is that not all parts of the body accelerate in the same way wh
INTRODUCTION: Using Swedish nationwide registry data, we investigated the contribution of genetic and environmental risk factors to the etiology of smoking status across stages of pregnancy with increasing degrees of social and psychological pressure to reduce or quit smoking, by twin and sibling modeling. AIMS AND METHODS: Smoking status was available before, and during early and late pregnancy f
As the COVID-19 pandemic intensified the global health crisis, the containment of SARS-CoV-2 infection in pregnancies, and the inherent risk of vertical transmission of virus from mother-to-fetus (or neonate) poses a major concern. Most COVID-19-Pregnancy patients showed mild to moderate COVID-19 pneumonia with no pregnancy loss and no congenital transmission of the virus; however, an increase in
Earth observation-based estimates of global gross primary production (GPP) are essential for understanding the response of the terrestrial biosphere to climatic change and other anthropogenic forcing. In this study, we attempt an ecosystem-level physiological approach of estimating GPP using an asymptotic light response function (LRF) between GPP and incoming photosynthetically active radiation (P
The coronavirus disease 2019 (COVID-19) pandemic has had a significant impact on the world of sports due to periods of home quarantine, bans against public gatherings, travel restrictions, and a large number of postponed or canceled major sporting events. The literature hitherto is sparse, but early indications display signs of psychological impact on elite athletes due to the pandemic. However, b
The Quaternary East Asian summer rainfall evolution reconstructed with the Chinese speleothem δ18O records shows the consistency throughout the region of East Asia, and has long been considered equivalent to the monsoon intensity. Its variation and teleconnection with global climate were usually interpreted by the meridional shift of the intertropical convergence zone (ITCZ). However, many other p
This study was aimed at finding a correlation between the experienced off-flavor in packed foods and the presence of specific degradation products in LDPE packaging films. The possibility to trap degradation products by chemical reactions with scavengers, i.e., a zeolite additive or antioxidants, was investigated This would prevent degradation products from migrating to the polymer film surface an
Background: There has been a controversy regarding the cause of brachioradial pruritus: is it caused by a nerve compression in the cervical spine or is it caused by a prolonged exposure to sunlight? Objective: The purpose was to study clinical features of patients with brachioradial pruritus and to compare the cutaneous innervation in punch biopsies from the itchy skin of patients with the age-mat
