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Background: Helicobacter pylori causes peptic ulcer disease and gastric cancer, and the oral cavity is likely to serve as a reservoir for this pathogen. We investigated the binding of H. pylori to the mucins covering the mucosal surfaces in the niches along the oral to gastric infection route and during gastric disease and modeled the outcome of these interactions. Materials and Methods: A panel o
Piloderma sp., a wood ash-colonizing ectomycorrhizal (EM) fungus, was grown symbiotically with Norway spruce in microcosms which contained granules of hardened wood ash. Mycelium close to the granules was sampled 3 times over a period of 11 weeks and the elemental content was investigated with particle induced X-ray emission. Mycelium from microcosms without wood ash was used as controls. The cont
The variations in atmospheric radiocarbon (C-14) concentration during the last 50 000 years can be attributed to changes in the C-14 production rate (due to changes in solar activity, the geomagnetic field and/or interstellar galactic cosmic ray flux) and to changes in the global carbon cycle. The relative contributions of these processes is the subject of current debate. Although the discrepancie
The electron acceptors acetoin, acetaldehyde, furfural, and 5-hydroxymethylfurfural (HMF) were added to anaerobic batch fermentation of xylose by recombinant, xylose utilising Saccharomyces cerevisiae TMB 3001. The intracellular fluxes during xylose fermentation before and after acetoin addition were calculated with metabolic flux analysis. Acetoin halted xylitol excretion and decreased the flux t
The basic helix-loop-helix (bHLH) proteins control differentiation and development of a variety of organs. We have isolated the complementary DNA (cDNA) of a novel class of bHLH transcription factors. The previously uncharacterized bHLH messenger RNA (mRNA) was identified by RNA fingerprinting by comparing embryonic and adult mRNA. The reading frame sequence predicts a new class of bHLH family. No
AIMS: A method was developed and evaluated to simultaneously register intraabdominal pressure (IAP) and intravesical pressure (IVP) during cystometry in conscious rats. In addition, IAP and IVP were recorded in rats with experimental detrusor overactivity (DO). METHODS: Sprague Dawley rats (n = 24) were used. Six female rats were subjected to partial bladder outlet obstruction for 2 weeks. A cathe
The recovery the alkaline solvent from of a residual stream after the extraction of hemicelluloses in wheat bran was investigated. The solution was withdrawn from an ultrafiltration (UF) process in which hemicelluloses were recovered. The UF permeate, containing mainly NaOH, lignin and mono- and oligosaccharides, was treated by nanofiltration (NF). Seven NF membranes were tested in a parametric st
Objective. Recent evidence suggests that hematopoietic stem cells (HSCs) in the bone marrow (BM) are located in areas where the environment is hypoxic. Although previous studies have demonstrated positive effects by hypoxia, its role in HSC maintenance has not been fully elucidated, neither has the molecular mechanisms been delineated. Here, we have investigated the consequence of in vitro incubat
Antibacterial peptides of the innate immune system combat pathogenic microbes, but often have additional roles in promoting inflammation and as growth factors during tissue repair. Midkine (MK) and pleiotrophin (PTN) are the only two members of a family of heparin-binding growth factors. They show restricted expression during embryogenesis and are upregulated in neoplasia. In addition, MK shows co
We have analyzed the geochemistry and mineralogy of the five characteristic beds that constitute the Dababiya Quarry Member (DQM) recovered from the Dababiya Quarry Core located near the Global Stratotype Section and Point (GSSP) for the base of the Eocene. Well developed in Upper Egypt, these beds are known to record the isotopic and biotic signatures of the Paleocene/Eocene thermal maximum (PETM
Objectives: Few studies have examined how lifestyle factors affect functional gastrointestinal disorders. The aim of this study was to see if leisure time physical inactivity, dietary habits or body mass index (BMI) were associated with increased risk of functional abdominal pain, functional bloating, functional constipation or functional diarrhea. Methods and materials: This study was based on a
Purpose - The purpose of this paper is to present numerical investigation of the gas/vapor bubble dynamics under the influence of an ultrasonic field to give a more comprehensive understanding of the phenomenon and present new results Design/methodology/approach - In order to formulate the mathematical model, a set of governing equations for the gas inside the bubble and the liquid surrounding it
During pregnancy and involution, an extensive remodelling of the human cervical connective tissue occurs. This cervical ripening is one of the most pronounced physiological remodelling processes known in human connective tissue. To investigate how the remodelling is accomplished, the levels of mRNA for collagen I and III, versican and three small proteoglycans, biglycan, decorin and fibromodulin,
Respiratory allergic disease represents a global health problem, 30% of the population suffers from allergic rhinoconjunctivitis and 20% suffer from asthma. Allergy immunotherapy induce immunological tolerance and thereby modify the response to allergens and sublingual immunotherapy (SLIT) offers the possibility of home administration of allergen therapy, but adherence is more uncertain. The aim o
Research on recruitment shows that networks matter and are effective as search channels. The aim of this article is to analyse how recruitment practices varies over time, and specifically, how it has varied before, during, and after the Great Recession 2008–2009. The findings are that recruitment practices change both in the short term, in relation to labour supply, which we can call a cyclical ef
The extent of the hypoxic area in the Baltic Sea has rapidly expanded over the past century. Two previous phases of widespread hypoxia, coinciding with the Holocene Thermal Maximum (HTM; 8–4ka before present; BP) and the Medieval Climate Anomaly (MCA; 2–0.8ka BP), have been identified. Relatively little is known about bottom water redox conditions in the coastal zone of the Baltic Sea during the H
Dynamic changes in absolute residual PME activity in potato tubers undergoing blanching were analysed with regard to the temperature distribution in the tissue after the treatment. The finite-element technique was used to predict the temperature distribution within the tissue during blanching. The temperature-related behaviour of the enzyme indicated that blanching between 60 and 70 degreesC induc
