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The relation between extreme heat and ENSO and characterization of health risks in relation to varying levels of UTCI

As a result of climate change, temperatures have been steadily increasing in the last half century and extreme weather events such as storms, extreme heat, extreme precipitation and cold spells have been observed to occur more frequently. This comes with potential consequences for lives and health. There are several factors affecting the climate in a region. A phenomenon that has a large impact in

Utforskning av digitalt hjälpmedel för förbättrad munhygien hos kognitivt sjuka i hemvården

A growing population with increasing life expectancy means that the proportion of cognitively ill people is increasing. This puts pressure on the home care service due to lack of time and resources, which leads to a decline in the well-being and quality of life of care recipients. A consequence of cognitive illness is memory loss, which leads to everyday chores such as toothbrushing often being fo

Infants with colic - Parents’ experiences in short and long perspectives and the effect of acupuncture treatment on crying, feeding, stooling and sleep

Popular Abstract in Swedish Spädbarn med kolik – föräldrars upplevelse i ett kortare och ett längre perspektiv samt effekten av akupunktur på barnets skrik, ätande, avföringsmönster och sömn. Spädbarnskolik definieras som ett tillstånd där ett för övrigt friskt barn skriker och gnäller mer än tre timmar per dag mer än tre dagar i veckan. Kolik drabbar ca 10 % av nyfödda barn i västvärlden. Både bInfantile colic, involving an otherwise healthy infant crying and fussing more than three hours per day and more than three days per week, is a common problem in Western countries. Both the infant and the parents suffer during the months of persistent crying and there is a risk that the establishing of the early relationship might be disturbed. Safe and effective treatment that provides relief in

Glycoproteomic identification of galectin-3 and -8 ligands in bronchoalveolar lavage of mild asthmatics and healthy subjects.

BACKGROUND: Galectins, a family of small carbohydrate binding proteins, have been implicated in regulation of inflammatory reactions, including asthma and fibrosis in the lungs. Galectins are found in cells of the airways and in airway secretions, but their glycoprotein ligands there have only been studied to a very limited extent. METHODS: Bronchoalveolar lavage (BAL) fluid from mild asthmatics a

Using the concentration-dependence of respiration arising from glucose addition to estimate in situ concentrations of labile carbon in grassland soil

In this study, we first determined the low molecular weight dissolved organic carbon (LMW DOC) concentration-dependent kinetics of soil respiration in a temperate grassland soil sampled on successive occasions. We then used the established relationship to estimate in situ LMW DOC concentrations from basal respiration measurements. C-14-labelled glucose was used as a model substrate and was added t

Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation

Rationale: Galectin-3 (Gal-3) drives fibrosis during chronic lung injury, however, its role in acute lung injury (ALI) remains unknown. Effective pharmacological therapies available for ALI are limited; identifying novel concepts in treatment is essential. GB0139 is a Gal-3 inhibitor currently under clinical investigation for the treatment of idiopathic pulmonary fibrosis. We investigate the role

The clinical consequence of using less than four sensory perception examination methods in the Swedish surveillance system for Hand-Arm vibration syndrome

OBJECTIVES: The Swedish surveillance system aiming to reveal undetected Hand-Arm Vibration Syndrome (HAVS) in workers exposed for vibrations is regulated by the provision AFS 2019:3. The goal for the surveillance system is to diagnose HAVS, as well as to find workers at risk for developing HAVS due to other conditions. The national guidelines stipulate examination using at least two out of four ha

Toward a multifunctional nature-based coastal defense: a review of the interaction between beach nourishment and ecological restoration

Coastal protection has evolved from focusing on hard solutions such as breakwaters and groynes to include soft or nature-based solutions (NbS). NbS have been pro- posed as cost-effective means to offer long-term coastal protection and at the same time strengthen coastal resilience and biodiversity. However, projects utilizing NbS for coastal protection have often focused on a single solution and t

The Potential of Small-Scale Urban Greening Interventions for Heat Mitigation and Biodiversity Conservation. A Neighbourhood-Scale Case Study in Cologne, Germany

Urban green infrastructure (UGI) is gaining popularity for disaster risk reduction and climate change adaptation in urban contexts, but dense development obstructs the realisation of large-scale greening measures. This thesis investigates the potential of small-scale, site-specific urban greening in a residential area in Cologne, Germany, to improve ecosystem service supply. The objective is to as

A comprehensive review of six dietary polyphenols in colorectal cancer : Pharmacokinetics, mechanism and therapeutic potentials

Background Colorectal cancer (CRC) remains a major global health challenge with high morbidity and mortality despite advances in detection and treatment. Dietary polyphenols are secondary metabolites widely found in plant-derived foods and beverages, and have gained attention for their potential in CRC prevention and therapy due to their diverse biological activities. Methods This review synthesiz

Influences of energy-efficient design and technologies on residents’ behaviour : Post-occupancy evaluation of multifamily buildings

No significant reduction in energy use has been observed in residential and service sector in Sweden during the last two decades, despite the introduction of energy efficient design and technologies. Residents’ preferences and behaviour are pointed out as the main factors affecting whether energy efficiency in residential buildings can be achieved. Moreover, there may be a risk of rebound effects

Critical flows throughout the Covid-19 pandemic – A longitudinal study on interdependencies and resilience in a Swedish context

Modern societies rely on critical flows of essential goods and services to ensure societal safety. The covid-19 pandemic highlighted the importance of upholding critical flows during a crisis. This comprehensive study provides novel insights into interdependencies and resilience of critical flows by carrying out a longitudinal and holistic study throughout the pandemic in Sweden of four sectors: t

Cervical cancer in Region Skåne, Sweden 2017–2020 after the implementation of primary HPV screening : A quality assurance audit

Introduction: Primary human papilloma virus (HPV) screening to detect cervical cancer and dysplastic lesions was implemented in Region Skåne 2017 for women aged 30–70. The aim of this study was to characterize the screening history of women diagnosed with cervical cancer to evaluate the performance of the screening program, as well as to assess the cancer treatments given and shortcomings in the f

Silica seed particles improve the efficiency and throughput of nanoparticle acoustic trapping

Silica has rarely been used as a seed particle material in acoustic trapping of nanoparticles. Here we use fluorescent nanoparticles, which are frequently used as a model system, to demonstrate that throughput and nanoparticle trapping efficiency can be improved by using silica seed particles as opposed to traditionally used polystyrene seed particles. The 10 times larger dipole scattering coeffic

Relationship between number of different lower-limb resistance exercises prescribed in a program and exercise outcomes in people with knee osteoarthritis : A systematic review with meta-regression

OBJECTIVE: Determine whether there is a relationship between the number of different lower-limb resistance exercises prescribed in a program and outcomes for people with knee osteoarthritis.METHODS: Systematic review with meta-regression. We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, and Embase up to 4th January 2024. We included randomised controlled trials th

Heterogeneously catalyzed lignin depolymerisation in continuous flow : Assessing feedstock pretreatment and catalyst deactivation

Due to the large-scale production of lignin, continuous flow reactors are preferred for its further valorization through depolymerization. However, there is limited literature on their use in lignin depolymerization, especially concerning feedstock pretreatments and catalyst deactivation. Therefore, in this study, the impact of a batch solvolysis pretreatment on the mild reductive catalytic depoly

Comparison between the EKFC-equation and machine learning models to predict Glomerular Filtration Rate

In clinical practice, the glomerular filtration rate (GFR), a measurement of kidney functioning, is normally calculated using equations, such as the European Kidney Function Consortium (EKFC) equation. Despite being the most general equation, EKFC, just like previously proposed approaches, can still struggle to achieve satisfactory performance, limiting its clinical applicability. As a possible so

Using past performance as an award criterion in EU public procurement.

The outcome of a procurement process largely depends upon how it was designed e.g. the terms and conditions that evaluates on what criteria a supplier is awarded a contract. In private sector procurement, evaluation of past performance is natural part of the evaluation process procurement. In public procurement there are more limited possibilities to evaluate past performance based on the rules an

Climate Impact on Dissolved Organic Carbon Composition in a North-Temperate Peatland and Recipient Surface Water

Climate may regulate dissolved organic carbon (DOC) composition across the peat-water interface, but experimental evidence is scarce. We manipulated the climate in peatland and recipient surface water mesocosms to reflect four different climate warming scenarios. In half of the mesocosms, the water level was managed to avoid drought, after which responses were recorded during two annual cycles. It