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Detection and removal sentinel lymph nodes (SLN) is important in the diagnosis and treatment of breast cancer and malignant melanoma. The SLN is the first regional lymph node draining the cancer tumor and if the cancer has spread it is most likely to find cancer cells in the SLN. In this study we have been able to detect multimodal superparamagnetic iron oxide nanoparticles (SPIO-NP) in rat SLNs i
Inflammatory challenges of the airway mucosa cause luminal entry of bulk plasma. Extravasation of plasma is well described but the routes for epithelial passage of plasma are largely unknown. Using colloidal gold (5 nm) as tracer we have now examined the fate of extravasated plasma in the airways. The tracer was given intravenously to anaesthetized, ovalbumin-sensitized guinea-pigs 2min prior to a
A shear-enhanced, cross-flow ultrafiltration module was used to separate cells and proteins from the fermentation broth. Three (fermented) media were studied: rich medium, rich medium with hydrolytic enzymes added after fermentation, and wheat flour hydrolysate. To find a membrane with as high a flux as possible, but still capable of separating cells and proteins from the lactic acid containing br
BACKGROUND: Cannabinoid (CB) receptors may be involved in the control of bladder function; the role of CB receptor subtypes in micturition has not been established. OBJECTIVES: Our aim was to evaluate the effects of cannabinor, a novel CB2 receptor agonist, on rat bladder function. DESIGN, SETTING, AND PARTICIPANTS: Sprague Dawley rats were used. Distribution of CB2 receptors in sensory and cholin
Cytogenetic analyses of a consecutive series of 67 paediatric (median age 8 years; range 0-17) de novo acute myeloid leukaemia (AML) patients revealed aberrations in 55 (82%) cases. The most common subgroups were KMT2A rearrangement (29%), normal karyotype (15%), RUNX1-RUNX1T1 (10%), deletions of 5q, 7q and/or 17p (9%), myeloid leukaemia associated with Down syndrome (7%), PML-RARA (7%) and CBFB-M
Chondrocytes isolated from the Swarm rat chondrosarcoma were incubated in culture with [1-3H]glucose for 30 min to 8 h. Labeled proteoglycans were isolated, treated with borohydride under alkaline conditions, and the three complex sugar structures purified: N- and O-linked oligosaccharides and chondroitin sulfate chains. The amount of incorporated radioactivity into each component sugar was analyz
Observations of sea level and precipitation in Malmö, Sweden in the southeastern part of the sound Öresund have been used to estimate the probabilities of local compound events of high sea level and large daily and hourly rains. There are observations of sea level and daily rains extending back to 1930. The observations of short-term rainfall are from 1980 and onwards. Most large rainfalls come in
Fms-like tyrosine kinase (FLT3) is a frequently mutated oncogene in acute myeloid leukemia (AML). FLT3 inhibitors display promising results in a clinical setting, but patients relapse after short-term treatment due to the development of resistant disease. Therefore, a better understanding of FLT3 downstream signal transduction pathways will help to identify an alternative target for the treatment
The Loess Plateau is one of the most severely affected regions in China by soil erosion, where vegetation restoration is the principal strategy for soil and water conservation. Runoff and sediment reduction benefits (RRB and SRB) are key indicators used to evaluate the effectiveness of vegetation measures. While numerous observational and experimental studies have explored the effects of different
Azurocidin is a multifunctional endotoxin-binding serine protease homolog synthesized during the promyelocytic stage of neutrophil development. To characterize the biosynthesis and processing of azurocidin, cDNA encoding human preproazurocidin was stably transfected to the rat basophilic leukemia cell line RBL-1 and the murine myeloblast-like cell line 32D cl3; cell lines previously utilized to st
Externally bonded reinforcement (EBR) was used to increase load bearing capacity of light weight aggregate concrete (LWA) masonry walls subjected to eccentric axial compression. Ladder type masonry reinforcement, high strength steel wire strips and glass fiber mesh were used for strengthening of eleven, 2.4 m high, 0.5 m long and 0.1 m thick walls. The reinforcement was applied on the dry wall sur
Barley husks, rye bran, and a fiber residue from oat milk production were processed by heat pretreatment, various separation steps, and treatment with an endoxylanase in order to improve the prebiotic potential of these cereal byproducts. Metabolic functions were intended to improve along with improved microbial activity. The products obtained were included in a high-fat mouse diet so that all die
This master’s thesis is about digital history and digital documents, studying attitudes and practises concerning this in some non-profit organizations. The study centres on how creators of archives handle their digital presence and on what they think about their digital material as part of their future history. The study has two main theoretical starting points: one in document theory, centring
Agenda 2030 Graduate School monthly newsletter #5 2023-06-12 Ylva van Meeningen Hi! Yesterday was sunny. Today it is sunny. And tomorrow will be sunny (in Lund at least). It feels somewhat wrong to complain about having clear and sunny skies for about a month, but you also start to wonder what would happen if there is no rain soon. What will happen with the crops, the forests, the insects and othe
With the diminishing reserves of oil and the growing public concern for environmental issues, the end of gasoline powered vehicles is getting closer each year. To prevent this from causing the personal and comfortable way of transportation mankind has gotten used to, to die with them, an alternative without the downsides of the gasoline engine must be developed. The environmentally friendly electr
A combination of acoustic trapping and impedance spectroscopy for micrometer-sized objects is here presented for the first time. Acoustic trapping has proven to be a well-functioning method for non-contact immobilization and positioning of particles or cells in microfluidic channels. The combination with impedance spectroscopy allows for simultaneous electrical measurements on the trapped objects.
Ideas regarding women, womanhood, and femininity are and always have been a controversial as well as ever-changing and evolving subject, which has occupied the thoughts of a number of men and women throughout history and keeps doing so. The subject of this paper is to study some views on femininity, womanhood, and female strength and worth, in a certain time, place, and cultural context, as well a
The aim of this master’s thesis is to examine the preservation of audiovisual objects and how methods surrounding this may affect the material as well as the archival profession. Physical recording formats – such as cassette tapes or compact discs – deteriorate quickly and are becoming progressively obsolete, which in turn makes it problematic to safeguard the information they contain. It is there
Operators of complex systems (e.g. modern passenger Commercial Aircrafts) often take decisions in unique situations, which develop rapidly in everyday work. For most situations, they have detailed company policies and procedures at their disposal to help them deal with these events. But do these procedures and policies work exactly as written all the time? And does experience level and type of org
The aim of this study is to understand how individuals construct their workplace at home, while they work from home digitally during the corona pandemic. The method through which the study has been conducted in order to achieve its aim is qualitative interviews. These were constructed to be held in the digital format of a digital communication software. The same format in which all e-workers have
