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Exposure of cells to adverse environmental conditions invokes a genetically programmed series of events resulting in the induction of specific genes. The fluoroquinolone antibiotic ciprofloxacin has recently been reported to upregulate interleukin-2 (IL-2) gene induction. In the present investigation, the effect of ciprofloxacin at supratherapeutic concentrations on immediate-early (<2 h) gene exp

The current climate change is calling for a drastic reduction of energy demand as well as of greenhouse gases. Besides this, cities also need to adapt to face the challenges related to climate change. Cities, with their complex urban texture and fabric, can be represented as a diverse ecosystem that does not have a clear and defined boundary. Multiple software tools that have been developed, in re

The dogroses (Rosa Sect. Caninae) are characterized by a unique meiosis - the canina meiosis - that results in restricted recombination. In the present study, we investigate population differentiation and morphometric diversity within six taxa, of Nordic dogroses, with the help of automated image analysis of leaflet shape and manually-measured reproductive characters. The total morphometric divers

The relevance of institutions for regional development has been well established in economic geography. In this context, local and regional governments play a central role, particularly through place-based and place-sensitive strategies. However, systematic and scalable insights into their priorities and strategies remain limited due to data availability. This paper develops a methodological appro

Introduction: Proactive and easily accessible interventions are needed to support people with long-term health conditions who experience limitations in activities of everyday life. However, there is a lack of interventions that promote self-management skills that prevent deterioration and improve health. The internet-based programme 'Strategies for Empowering Activities in Everyday Life' (SEE) sup

Historical slag dumps are of increasing interest due to economic, environmental or archaeological reasons. Geophysical investigations can help accessing the potential reuse of slag material to recover metallic raw material or for the estimation of the hazard potential of the buried slag material due to dissolution occurrence.In our study, we have investigated various slag material in the laborator

While prior studies have largely addressed corporate social responsibility (CSR) at a macro or institutional level, its importance at the micro or individual level is to date underexplored, especially in the context of developing economies. Further, it is not clear from the studies in the extant literature how the role of females is more important in the context of environmental management as comp

The aim was to describe food intake over time in children and adolescents, with respect to age and gender. The present study was a repeated cross-sectional study using self-reported data from a health questionnaire. Data were collected from the School Health Services in south-east Sweden from 44 297 students, 10, 13-14 and 16 years of age, 48 % girls and 52 % boys from 2009/2010 to 2015/2016. Repo

Increasing land use pressure is a primary force for degradation of agricultural areas. The drivers for these pressures are initiated by a series of interconnected processes. This study presents a novel methodology to analyze drivers of changing land use pressure and the effects on society and landscape. The focus was on characterizing these drivers and relate them to land use statistics obtained f

Prior literature in the field of corporate social responsibility (CSR) has largely focused on investigating its relationship with organizational-related outcomes, whereas the impact of CSR on consumer behavior is largely ignored in the recent literature. Further, most of the prior studies have investigated CSR with a philanthropic viewpoint, but its importance in achieving marketing-related outcom

Globally, northern peatlands are major carbon deposits with important implications for the climate system. It is therefore crucial to understand their spatial occurrence, especially in the context of peatland degradation by land cover change and climate change. This study was aimed at mapping peatlands in the forested landscape of Sweden by modelling soil data against lidar-based terrain indices.

The objective of this work was to produce a gluten-containing food matrix (pasta) rich in dietary fiber (DF), polyphenols, and antioxidant activity, through partial substitution with a dry flour from decocted Hibiscus sabdariffa L. calyces. The food matrix was made by mixing semolina (75%) and decocted calyces flour (25%) (S75–HF25), and its proximate composition, polyphenols content, antioxidant

Syftet med denna licentiatavhandling är att bidra till en ökad förståelse för hurräddningstjänsten kan förbättra sin förmåga att lösa komplexa problem vidstorskaliga olyckshändelser. Större olyckor är ofta komplexa och dynamiskahändelser som kännetecknas av en hög grad av osäkerhet, oförutsägbarhet ochtvetydighet. Under sådana förhållanden utmanas räddningstjänstens förmåga att lösa de olika och mGlobal trends suggest an increasing level of uncertainty regarding potential risks faced by individuals, organizations, or society as a whole. These trends are likely to alter the risk landscape, necessitating the enhancement of societal capabilities to effectively address emerging risks. Among the key actors dealing with such changes is the Fire and Rescue Service (FRS). However, these challenges

The expansion of the electric vehicle industry is driving increased demand for lithium-ion batteries (LIBs), which in turn creates challenges in material availability and waste management that more durable LIBs could address. Electrode surface coating helps extend LIB lifespan, with atomic layered deposition (ALD) as the preferred method due to its precise thickness control and ability to coat var

Microplastic (MP) pollution is increasingly recognized as a critical issue in coastal environments, where complex interactions between ocean currents, winds, waves, and human activities govern the transport and deposition of synthetic particles. Although previous studies in Asia have documented MPs accumulation linked to riverine discharge, tourism pressures, and monsoonal circulation, limited wor

In the future, buildings need to be energy resilient to tackle the energy crisis. This article introduces a concept for classifying the energy resilience of buildings in extreme cold and warm weather in Finland during blackouts. It presents a techno-economic comparison between an old and a new single-family building integrated with photovoltaic (PV) systems and batteries, analyzing their resilienc

Building more energy-efficient and sustainable urban areas that will both mitigate the effects of climate change and anticipate living conditions in future climate scenarios requires the development of new tools and methods that can help urban planners, architects and communities achieve this goal. In the current study, we designed a workflow that links different methodologies developed separately

The scale at which greenhouse gases are produced by human activities is a global problem, and as such it is being targeted broadly both by political means as well as technologically. One of the major contributors to the emission of green house gases globally, as well as in Sweden, is the transportation sector. This poses an opportunity for technologies that aim to reduce impact of the transport se

Bone is a composite material where tubular osteon structures surrounded by thin interfaces reinforce the tissue at the microscale. These interfaces provide alternative weak paths for crack growth and give rise to potent extrinsic toughening mechanisms. Numerical models can help to gain a deeper understanding of fracture resistance in bone, however, capturing the interface mechanics is key. For thi

AIM: This study investigated childhood diagnoses in children born extremely preterm before 24 weeks of gestation.METHODS: Diagnoses of neurodevelopmental disorders and selected somatic diagnoses were retrospectively retrieved from national Swedish registries for children born before 24 weeks from 2007 to 2018. Their individual medical files were also examined.RESULTS: We studied 383 children born