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Recombinant factor IX Fc for the treatment of hemophilia B
Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E
Reply to Pandey: IgG3 allotypes, modulation of antigen binding by constant domain changes, and therapeutic applications of Fc engineering
A Monosaccharide Residue Is Sufficient to Maintain Mouse and Human IgG Subclass Activity and Directs IgG Effector Functions to Cellular Fc Receptors.
Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly
Functional Variants of Fc Gamma Receptor (FCGR2A) and FCGR3A Are Not Associated with Susceptibility to Systemic Sclerosis in a Large European Study (EUSTAR).
OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>
Utvc21 ht 2017 schedule 2017-05-04tb
BIDS UTVC21 Lectures and seminars 2017 (Updated 2016-04-06) Date Time Room Theme Activity Group Lecturer 30/8 10-12 Världen Meet Your Programme Coordinator Lec 1/1 AF 30/8 13-15 Världen Registration and Introduction Lec 1/1 TAX 1/9 10-12 Världen Introduction: questioning development Potter Ch. 1; Allen et al Ch. 1-2 Lec 1/1 YM 1/9 13-15 Världen Introduction: history and development Allen Ch. 1; Al
https://www.keg.lu.se/sites/keg.lu.se/files/utvc21_ht_2017_schedule_2017-05-04tb.pdf - 2025-11-21
Utvc21 ht 2017 schedule 2017-09-13
BIDS UTVC21 Lectures and seminars 2017 (Updated 2017-09-13) Date Time Room Theme Activity Group Lecturer 30/8 10-12 Världen Meet Your Programme Coordinator Lec 1/1 AF 30/8 13-15 Världen Course Introduction Lec 1/1 TAX 1/9 10-12 Världen Introduction: questioning development Potter Ch. 1; Allen et al Ch. 1-2 Lec 1/1 YM 1/9 13-15 Världen Introduction: history and development Allen Ch. 1; Allen et al
https://www.keg.lu.se/sites/keg.lu.se/files/utvc21_ht_2017_schedule_2017-09-13.pdf - 2025-11-21
Utvc21 schedule autumn2017 updated 2018-08-08
BIDS UTVC21 Lectures and seminars 2017 (Updated 2017-08-08) Date Time Room Theme Activity Group Lecturer 30/8 10-12 Världen Meet Your Programme Coordinator Lec 1/1 AF 30/8 13-15 Världen Course Introduction Lec 1/1 TAX 1/9 10-12 Världen Introduction: questioning development Potter Ch. 1; Allen et al Ch. 1-2 Lec 1/1 YM 1/9 13-15 Världen Introduction: history and development Allen Ch. 1; Allen et al
https://www.keg.lu.se/sites/keg.lu.se/files/utvc21_schedule_autumn2017_updated_2018-08-08.pdf - 2025-11-21
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Utvc21 ht 2017 schedule 2017-09-29
BIDS UTVC21 Lectures and seminars 2017 (Updated 2017-09-29) Date Time Room Theme Activity Group Lecturer 30/8 10-12 Världen Meet Your Programme Coordinator Lec 1/1 AF 30/8 13-15 Världen Course Introduction Lec 1/1 TAX 1/9 10-12 Världen Introduction: questioning development Potter Ch. 1; Allen et al Ch. 1-2 Lec 1/1 YM 1/9 13-15 Världen Introduction: history and development Allen Ch. 1; Allen et al
https://www.keg.lu.se/sites/keg.lu.se/files/utvc21_ht_2017_schedule_2017-09-29.pdf - 2025-11-21
Matrix metalloproteinase-26 (MMP-26) and Tissue inhibitor of metalloproteinases-4 (TIMP-4) in normal, hyperplastic, and malignant endometrium.
A surface-exposed GH26 -mannanase from Bacteroides ovatus : Structure, role, and phylogenetic analysis of BoMan26B
Backbone 1 H, 13 C, and 15 N resonance assignments of BoMan26A, a β-mannanase of the glycoside hydrolase family 26 from the human gut bacterium Bacteroides ovatus
How does player motivation express in actual game play? A cross-cultural quantitative case study of Tom Clancy’s The Division 2
Previous studies have proven that player motivation is tightly intertwined with players' self-reported game-related behaviors, but how does player motivation express in actual game play? In addition, does cultural background matter? The current study selected Tom Clancy's The Division 2, a popular tactical third person shooting action role-playing game, as the research target, investigatin