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Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly

Pufendorfinstitutet

Pufendorfinstitutet är ett tvärvetenskapligt institut med syfte att stimulera till samarbete mellan forskare från olika discipliner inom Lunds universitet. I "Teman" och" Advanced Study Groups" ges forskare från alla universitetets fakulteter möjlighet att tillsammans utforska vetenskapliga problem .The Pufendorf Institute for Advanced Studies is an interdisciplinary institute with the aim to stimulate collaboration between researchers from different disciplines within Lund University. In "Themes" and "Advanced Study Groups", researchers from all faculties of the university are given the opportunity to jointly explore scientific issues.

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OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>

Avdelningen för translationell cancerforskning

Translationell cancerforskning bildades 2013 som en del av Lunds universitets cancercenter (LUCC) på Medicon Village. TCR består av nio grupper som arbetar med olika frågeställningar och tumörtyper, men med ett gemensamt mål att utveckla nya behandlingsmetoder. Frågeställningarna bearbetas multidisciplinärt med hjälp av cellbiologi, bioinformatik, musmodeller, humana vävnadsarrayer och avancerade The Division of Translational Cancer Research (TCR) was founded 2013 in conjunction with the formation of Lund University Cancer Center (LUCC) at Medicon Village. TCR consists of nine research groups with different areas of expertise, but together working on projects with the common goal of improving cancer diagnostics and cancer therapy. Our multidisciplinary experimental settings include human g

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Objective Blood cell populations, including red blood cells (RBC) unique to the extremely preterm (EPT) infant, are potentially lost due to frequent clinical blood sampling during neonatal intensive care. Currently, neonatal RBC population heterogeneity is not described by measurement of total haemoglobin or haematocrit. We therefore aimed to describe a subpopulation of large RBCs with hyper high

Avdelningen för industriell elektroteknik och automation

Forskningen är huvudsakligen tillämpningsorienterad och inspirerad av idustriella problem.[BR] Projekten utförs i samarbete med svensk industri på områdena elkraftsystem, tillverkningssystem,[BR] urbana vattensystem, elektriska drivsystem och elhybridfordonThe research is application oriented and inspired by industrial problems.[BR] Application areas are electric power systems, urban water systems,[BR] electric drives, power electronics, autonomous manufacturing systems [BR]and electro-hybrid vehicles.