Filetype
The distinct lineage potential is a key feature of hematopoietic stem cell (HSC) heterogeneity, but a subset of HSCs specialized for a single lymphoid compartment has not been identified. Here we report that HSCs expressing junctional adhesion molecule 2 (Jam2) at a higher level (Jam2high HSCs) have a greater T cell reconstitution capacity. Jam2high HSCs are metabolically dormant but preferentiall
RESEARCH DESIGN AND METHODS: We studied participants in PROVALID (PROspective cohort study in patients with type 2 diabetes mellitus for VALIDation of biomarkers), a prospective multinational cohort study of patients with type 2 diabetes and a follow-up of more than 24 months (n = 2,560; baseline median eGFR, 84 mL/min/1.73 m2; urine albumin-to-creatinine ratio, 8.1 mg/g). The 17 biomarkers were m
Tissue factor pathway inhibitor 2 (TFPI-2) is a matrix-associated serine protease inhibitor with an enigmatic function in vivo. Here, we describe that TFPI-2 is present in fibrin of wounds and also expressed in skin, where it is up-regulated upon wounding.
The objective was to study the development and progression of heart disease in type 2 diabetic patients and to evaluate the influence of revascularisation procedures on its outcome. A 10-year observation study in 385 patients attending a hospital-based outpatient clinic was performed. A total of 156/385 patients developed myocardial infarction (n=68), angina (n=44), heart failure (n=34) or died (n
Background: Early-life physical fitness has rarely been examined in relation to type 2 diabetes mellitus (DM) in adulthood because of the lengthy follow-up required. Elucidation of modifiable risk factors at young ages may help facilitate earlier and more effective interventions. Objective: To examine aerobic capacity and muscle strength at age 18 years in relation to risk for type 2 DM in adultho
The authors have developed a porous silicon (P-Si) based duplex antibody microarray platform for simultaneous quantitation of the biomarkers prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) in serum. Pore size-controlled P-Si surfaces have an extremely enlarged surface area that enables high-density immobilization of fluorescently labeled antibodies by physical adsorption. Au
To evaluate the shared genetic etiology of type 2 diabetes (T2D) and coronary heart disease (CHD), we conducted a genome-wide, multi-ancestry study of genetic variation for both diseases in up to 265,678 subjects for T2D and 260,365 subjects for CHD. We identify 16 previously unreported loci for T2D and 1 locus for CHD, including a new T2D association at a missense variant in HLADRB5 (odds ratio (
We assembled an ancestrally diverse collection of genome-wide association studies (GWAS) of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non-European descent) through the Diabetes Meta-Analysis of Trans-Ethnic association studies (DIAMANTE) Consortium. Multi-ancestry GWAS meta-analysis identified 237 loci attaining stringent genome-wide significance (P < 5 ×
Background and AimsOlder persons with problematic alcohol use vary in psychosocial functioning, age of onset for problem drinking and use of other drugs. The study measured the differential risks of all-cause, alcohol, polydrug and psychiatric-related repeated hospitalizations among older persons with problematic alcohol use.DesignA linked register-based cohort study with discontinuous multiple-fa
Clinical axillary lymph node management in early breast cancer has evolved from being merely an aspect of surgical management and now includes the entire multidisciplinary team. The second edition of the “Lucerne Toolbox”, a multidisciplinary consortium of European cancer societies and patient representatives, addresses the challenges of clinical axillary lymph node management, from diagnosis to l
NyhetsbrevVT15 Nyhetsbrev - Öresundsnätverket för kønshistorisk forskning Våren 2015 Öresundsnätverket för kønshistorisk forskning samlar forskare från olika discipliner i syfte att utveckla och stärka kønshistorisk forskning på båda sidor om Öresund. Kalendarium på båda sidor av sundet: “Racial politics, neoliberal rationalities and political activism” Med: Suvi Keskinen, University Lecturer in S
https://www.cors.lu.se/sites/cors.lu.se/files/nyhetsbrevvt15.pdf - 2026-07-09
Registerutdrag 1 (2) SK V 46 21 17 sv 00 03 * Skatteverket Registerutdrag 205 30 MALMÖ 0771-567567 2024-03-27 Datum 202100-3211 LUNDS UNIVERSITET Box 117 221 00 LUND Organisationsnummer Registreringar avseende skatteform, moms- och arbetsgivarregistrering Skatteform Godkänd för F-skatt fr.o.m. 1993-01-01 Registrerad för moms Vid framtidsdatum, se sid 2 Fr.o.m. 1979-07-01 SE202100321101 Momsreg.nr/
https://www.ekonomiwebben.lu.se/sites/ekonomiwebben.lu.se/files/2024-03/Registreringsbevis-LU.pdf - 2026-07-09
https://www.hr-webben.lu.se/guests-unit - 2026-07-07
