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Background: Under inflammatory conditions, T cell-dependent (TD) protein antigens induce proinflammatory T-and B-cell responses. In contrast, tolerance induction by TD antigens without costimulation triggers the development of regulatory T cells. Under both conditions, IgG antibodies are generated, but whether they have different immunoregulatory functions remains elusive. Objective: It was shown
By use of a batch microcalorimeter of the thermopile type, heat production was measured in isolated populations of human peripheral blood cells exposed to defined immune complexes formed in vitro. It was found that most of the heat production recorded in whole blood after admixture of immune complexes occurs in the granulocytes. Under these conditions small but constantly higher activation values
Aleksander Giwercman är forskargruppsledare för den här forskargruppenOur research focuses on clinical and epidemiological aspects of gene-environment interaction in relation to human reproductive function. The clinical base of our research is closely linked to the Reproductive Medicine Centre at Skåne University Hospital, Malmö. This enables us to study both male and female reproduction, separately and in combination. Some important subareas of research include spe
Lund Hemodynamic Lab was initiated in 2010 by Göran Rådegran in order to provide high quality investigations, essential in risk assessment in guidance of PAH therapies & listing for transplantation & utilizing myocardial biopsies in steering of immunosuppression to prevent rejection after transplantation.Lund Hemodynamic Lab was initiated in 2010 by Göran Rådegran in order to provide high quality investigations, essential in risk assessment in guidance of PAH therapies & listing for transplantation & utilizing myocardial biopsies in steering of immunosuppression to prevent rejection after transplantation.
Brosk och ben är vävnader som innehåller mycket extracellulär matrix. Sammansättningen av matrix bidrar till dess speciella egenskaper: brosket motstår belastning och ger låg friktion medan benet fungerar främst som support, skyddar inre organ och mjuka vävnader (tex hjärna, hjärta och lungor), fungerar som hävstång till musklerna i skapandet av rörelse men bidrar också med lagring av kalcium.Cartilage and bone are tissues that are rich in extracellular matrix. The composition of the extracellular matrix is responsible for their unique physical properties where cartilage withstands load and contribute to low-friction movements. Bone support and protect the various organs of the body, produce red and white blood cells and store minerals.
The overall goal of our research unit is to understand metabolic control of insulin secretion and why it fails in type 2 diabetes (T2D). In recent years, this has meant that we have used information from GWAS (Genome-wide association study) to direct our efforts towards the genes which are actually linked to the development of the disease. To reach this overarching goal, we have worked along tw
EFL är en icke-vinstdrivande stiftelse som arbetar med vidareutbildning inom Ekonomihögskolan vid Lunds universitet. Stiftelsen grundades 1969 av professorer och lärare vid Företagsekonomiska institutionen. Styrelsen består idag av en huvudman: Ekonomihögskolan vid Lunds universitet. EFL:s verksamhet grundar sig på tanken om nära relationer mellan näringsliv och universitet. Idag finns ett regiona
Forskningen inom avdelningen för Elektromagnetism och Nanoelektronik spänner över ett bredd områden från teoretisk elektroteknik och vågutbredning till nanoelektroniska komponenter och system. Tematiskt är forskningsområden indelade i 6 områden: Antenner och vågor, Metamaterial, Nanoelektronik för IoT, neuromorfa elektronik, kvantteknologi, THz och Kraftelektronik. Inom elektromagnetismen läggs sThe research within the Division of Electromagnetism and Nanoelectronics spans a wide range of areas from Electromagnetic Theory and wave propagation to nanoelectronic devices and systems. Thematically, research areas are divided into 6 areas: antennas and waves, metamaterials, nanoelectronics for IoT, neuromorphic computing, quantum technology, THz and Power electronics. Within the electromagnet
We are interested in how gene expression is regulated in the brain and how this process influence neurodegenerative diseases, psychiatric disorders and brain tumors. Our current focus is to study the role of epigenetic mechanisms and microRNAs. Our technical expertise include lentiviral vectors, transgenic mice and stem cells cultures.
Sektionen för muskuloskeletal radiologi bedriver forskning inom utveckling, utvärdering och användande av bilddiagnostiska metoder vid sjukdomstillstånd inom rörelseapparaten. Forskare vid sektionen driver olika projekt syftande till minskning av stråldoser vid användande av datortomografi, utvärdering av värdet av avancerade magnetresonanstekniker såsom användande av 7T ultrahög fältstyrka och anThe section for musculoskeletal radiology conduct research in fields related to the development, evaluation and application of imaging methods intended for diagnosis of musculoskeletal diseases. Our researchers conduct different projects aiming at reduction of radiation dose exposure when applying computed tomography, exploration of the value of advanced magnetic resonance imaging techniques such
