Filetype
Positive teacher-student and student-student relationships are among the most significant factors contributing to learning, motivation, wellbeing, and graduation rates in higher education. Trust is commonly understood as a key element for the development and sustenance of positive educational relationships, yet relatively little empirical research investigates trust in higher education classrooms.
Escape from cytotoxic T lymphocyte (CTL) responses toward HIV-1 Gag and Nef has been associated with reduced control of HIV-1 replication in adults. However, less is known about CTL-driven immune selection in infants as longitudinal studies of infants are limited. Here, 1,210 gag and 1,264 nef sequences longitudinally collected within 15 months after birth from 14 HIV-1 perinatally infected infant
Sociodemographic inequalities in student achievement are a persistent concern for education systems and are increasingly recognized to be intersectional. Intersectionality considers the multidimensional nature of disadvantage, appreciating the interlocking social determinants which shape individual experience. Intersectional multilevel analysis of individual heterogeneity and discriminatory accura
The rapid emergence of Generative Artificial Intelligence (GenAI) presents higher education with unprecedented opportunities to augment and enhance learning. As educators, learners, technologists and institutional leaders, we find ourselves navigating uncharted territory. How can we evaluate, integrate and govern these rapidly evolving technologies responsibly, so that they enrich rather than disp
Objectives: The aim of this study was to investigate whether a low-dose cone-beam computed tomography (CBCT) protocol provides diagnostically acceptable image quality for assessing bone healing after alveolar bone grafting. Material and Methods: The study cohort comprised 11 patients (aged 7–14 years) with orofacial clefts who had undergone alveolar bone grafting at Skåne University Hospital in Ma
Abstract Thiosilvatins are a family of biologically active sulfenylated diketopiperazine natural products. The first members were reported over 40?years ago, but total synthesis of a thiosilvatin has remained elusive. Here, we describe the first, collective, synthesis of the parent epidithiodiketopiperazine (?)-dithiosilvatin and ten related thiosilvatins. Several of the targets are structurally rThiosilvatins are a family of biologically active sulfenylated diketopiperazine natural products. The first members were reported over 40 years ago, but total synthesis of a thiosilvatin has remained elusive. Here, we describe the first, collective, synthesis of the parent epidithiodiketopiperazine (−)-dithiosilvatin and ten related thiosilvatins. Several of the targets are structurally revis
This guide is designed to supplement the 2024 Advance HE Framework for Enhancing Assessment Framework in Higher Education, which is part of a series of frameworks developed to promote student success. The Enhancing Assessment Framework draws on the findings of an extensive literature review Impacts of higher education assessment and feedback policy and practice on students: a review of the literat
Background: The association between physical frailty and performance in different cognitive domains in the absence of cognitive disorders is poorly understood. Hence, we aimed to explore the associations between frailty levels based on the Fried Physical Frailty Phenotype and performance of different cognitive domains. We also aimed to examine the associations between cognitive function and each c
Objective: Inverse associations between systemic inflammation and cholesterol (‘the lipid paradox’) have been reported in rheumatoid arthritis (RA) and, in established axial spondyloarthritis (axSpA), but little is known about this relationship in early axSpA, which is the focus of the present study. Method: In the Swedish part of the SPondyloArthritis Caught Early (SPACE) cohort (patients with ch
Objective Elite para athletes report a high incidence of sports injuries. Research suggests that athletes’ strategies to manage adversities may influence the sports injury risk, but knowledge about para athletes’ coping behaviours and their association with injuries is limited. The aim was to describe the distribution of coping behaviours in Swedish elite para athletes by sex, age, impairment, spo
Atopic dermatitis, food allergy, allergic rhinitis, and asthma are among the most common diseases in childhood. They are heterogeneous diseases, can co-exist in their development, and manifest complex associations with other disorders and environmental and hereditary factors. Elucidating these intricacies by identifying clinically distinguishable groups and actionable risk factors will allow for b
Overt and subclinical hyperthyroidism are associated with an increased fracture risk, but whether thyroid hormones are associated with fracture risk in individuals with normal thyroid-stimulating hormone (TSH) has mostly been investigated in women. Therefore, we investigated if serum levels of free thyroxine (FT4) or TSH are associated with fracture risk in Swedish men. We followed (median 12.2 yr
INTRODUCTION: Numerous studies have characterised trajectories of asthma and allergy in children using machine learning, but with different techniques and mixed findings. The present work aimed to summarise the evidence and critically appraise the methodology.METHODS: 10 databases were searched. Screening, data extraction and quality assessment were performed in pairs. Trajectory characteristics w
BackgroundIn the last three decades, the increasing trend in female employment in Bangladesh has been critically analyzed from a socioeconomic point of view; however, its impact on infant and young child feeding (IYCF) practices has yet to be systematically reviewed. The aim of this systematic review and meta-analysis is to investigate the association between these variables.MethodsA systematic li
Multilevel regression analysis (MLRA) is a statistical technique that is suitable for the study of correlated outcomes within multilevel organisational and other data structures. This chapter provides a short introduction to MLRA, stressing the multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA) approach. It helps the readers to recognize the presence of multilevel
Objective: This study examined the prevalence and long-term survival of atrial fibrillation (AF) in the older population. Methods: Data was recruited from the longitudinal SNAC study from baseline (2001–2004) for up to 10 years. Results: The population comprised 6,904 persons (59% women) (mean age 73.9 years). The prevalence of AF was 4.9% and increased with age. The hazard ratio (HR) for death in
Quantitative analysis of large-scale political text data in the form of word embeddings has great potential for systematising differences between political parties. We examine the differences between embeddings obtained from speakers from the two competitors for the PM position in Sweden (Social Democrats and Moderates) over a 30-year period. The goal is to compare how off-the-shelf general pre-tr
BackgroundPolypharmacy has been linked with social isolation and loneliness among older people. The roles of different medication groups to this association are unclear. The aim of this study was to examine associations of fall-risk-increasing drugs (FRIDs) and cardiovascular drugs with loneliness and social isolation.MethodsThis cross-sectional study included 6714 adults aged 60 years and above l
