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PURPOSE: The early loss of a parent is a tragedy and a serious life event. This study investigated grief resolution and morbidity in cancer-bereaved teenagers 6 to 9 years after the loss of a parent to cancer. METHODS: In a nationwide population-based study of 622 of 851 (73 %) youths who as teenagers 6 to 9 years earlier had lost a parent to cancer, we explored the magnitude of unresolved grief a

Elevated plasma cytokines is a common finding in Major Depressive Disorder (MDD), although not consistent. It is currently not known whether the inflammatory changes are confined to any specific subgroup of depressive patients. We here analyzed three inflammatory markers in suicidal and non-suicidal depressive patients, as well as healthy controls. Plasma interleukin (IL)-2, IL-6 and tumor necrosi

It is by now a common trope that youth climate activism has become a ‘global phenomenon’. Yet, it also has significant regional variations. This literature review analyses eighteen academic articles on the topic of youth climate activism in Asia. We found that the literature from Asia overall had ambitions to contextualise and nuance international scholarship on youth climate activism. This was ac

A common type of inhalation medicine uses a dry powder formulation where the active pharmaceutical ingredient (API) is attached on the surface of carrier particles, often in combination with additional components. The spatial distribution of the API on the carrier particle is critical for the release into the lungs and thus for the efficacy of the drug. In this work, we use ToF-SIMS imaging in com

Science, technology and innovation (STI) are widely perceived as critical factors for sustainable development. The 2030 Agenda defined STI as the central means of sustainable development. The Sustainable Development Goal 17 has three targets that focus on technology transfer, and the United Nations Technology Facilitation Mechanism was launched to promote multi-stakeholder collaboration. While STI

This paper deals with numerical investigations of cross laminated timber (CLT) beams. Previous investigations have revealed discrepancies between experimental test results and suggested design methods regarding shear force capacity of such beams. To gain further understanding of the failure behaviour and the shear force capacity, nonlinear finite element analyses have been performed, using a cohes

Background: Treatment with antihypertensives in patients with advanced cancer is often continued until very late in the disease trajectory, despite a considerable risk of hypotension. Objectives: The aim of this study was to investigate the time of deprescribing of antihypertensive agents in patients with cancer receiving palliative care during their last year of life. The monitoring of blood pres

The aim of this chapter is to explore the safety value of implementing Asimov's Laws of Robotics as a future general framework that humans should obey. Asimov formulated laws to make explicit the safeguards of the robots in his stories: (1) A robot may not injure or harm a human being or, through inaction, allow a human being to come to harm; (2) A robot must obey the orders given to it by human b

In urban property development projects, attention to the needs and aspirations of local communities is often neglected. Although some developers still consider local community stakeholders to be a potential threat to their developments, in many developed countries, stakeholder participation is embedded within statutory processes such as the formal planning process and is increasingly regarded as a

Glioblastoma presents a formidable clinical challenge because of its complex microenvironment. Here, we characterized tumor-associated foam cells (TAFs), a type of lipid droplet-loaded macrophage, in human glioblastoma. Through extensive analyses of patient tumors, together with in vitro and in vivo investigations, we found that TAFs exhibit distinct protumorigenic characteristics related to hypox

The construction sector needs to transition toward using bio-based building materials in order to reduce its negative environmental impact. However, it is unclear how exactly such a bio-based future will look like, with different stakeholders in different geographical contexts having different visions of the sector’s future. Based on an extensive collection of expert interviews with stakeholders f

Understanding and quantifying the global methane (CH4) budget is important for assessing realistic pathways to mitigate climate change. CH4 is the second most important human-influenced greenhouse gas in terms of climate forcing after carbon dioxide (CO2), and both emissions and atmospheric concentrations of CH4 have continued to increase since 2007 after a temporary pause. The relative importance

In low-and middle-income countries, inadequate sanitation results in faecal contamination of the water used by urban farmers for irrigation. Consumers of raw contaminated vegetables run the risk of developing diarrhoeal diseases and helminth infections, which are a leading cause of under-five mortality and impact the well-being and productivity of millions of adults. This review identifies the evi

Objectives: An increased interest in the phenomenon and process of compassion, in both clinical and non-clinical psychological research, has been seen in recent decades. In these contexts, compassion is frequently understood as a felt response to the suffering of others that involves caring and seeing the universal nature of human suffering, as well as an authentic desire to ease the distress. Bas