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Abstract The aim of my paper is to highlight on two works of woman –writers in yiddish literature, The memoirs of Glikl Hamel (1645-1741) and the lightly disguised auto-biographical novel, Deborah, by Esther Singer-Kreitman (1891-1954).The paper also describes the growth of the writers in strictly religious, Jewish families, Glikl´s in Germany, Esther´s in Poland. Personal crisis were starting-poi

Information and communication technologies (ICTs) become more advanced and more accessible which leads to new ways of work. A rather new phenomenon is that of location independent workers (LIWs), who are enabled by these technologies to work while traveling the world. New ways of working assumingly lead to changes in the work-nonwork interface. This study takes a demands and resources approach to

The global steel industry accounts for 8–10 % of global CO2 emissions and requires deep decarbonisation for achieving the targets set in the Paris Agreement. However, no low-emission primary steel production technology has yet been commercially feasible or deployed. Through analysing revisions and additions of European Union climate policy, we show that green hydrogen-based steelmaking in competit

Background: In 2007, the World Cancer Research Fund (WCRF) and the American Institute for Cancer Research (AICR) issued recommendations on diet, physical activity, and weight management for cancer prevention on the basis of the most comprehensive collection of available evidence. Objective: We investigated whether concordance with WCRF/AICR recommendations is related to risk of death. Design: The

Understanding how hematopoietic stem and progenitor cells (HSPCs) are regulated is of central importance for the development of new therapies for blood disorders and stem cell transplantation. To date, HSPC regulation has been extensively studied in vitro and in animal models, but less is known about the mechanisms in vivo in humans. Here, in a genome-wide association study on 13,167 individuals,

Background: Despite standard-of-care androgen-deprivation therapy and an increasing number of treatment options, the mortality rate for prostate cancer remains high. Progress to metastatic castration-resistant prostate cancer (mCRPC) necessitates additional treatments. Abiraterone acetate plus prednisone or prednisolone (AAP) prolongs survival in chemotherapy-naive and docetaxel-experienced patien

Membrane proteins play several important roles in a cell. Among these proteins are aquaporins (AQPs) and transient receptor potential (TRP) ion channels that mediate water transport, temperature and noxious chemical sensation, respectively. The function of some AQPs, for example the spinach isoform SoPIP2;1 is regulated by pH, phosphorylation and heavy metals such as mercury. However, the mechanis