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Despite being subject to a multitude of investigations, the effect of carrier particle size on the performance of adhesive mixtures for inhalation is still not well understood. This study, involving three differently sized lactose carriers, all with the regular ‘tomahawk’ particle shape, aims to provide fundamental insight into this topic. Fine particle fraction (FPF) data for binary formulations
Denna forskningsrapport inom ramen för ett MSB uppdrag identifierar och kartlägger relevanta datamängder för att bedöma tvärsektoriella sårbarheter för samhällsviktiga verksamheter och kritiska infrastrukturer på nationell svensk nivå. Totalt identifierades 108 datamängder, varav 49 bedöms vara relevanta för analyser på nationell nivå, 54 på regional nivå och 37 på lokal nivå. Identifierad och samThis commissioned research report identifies and maps out relevant data sets to assess cross-sectoral vulnerabilities of vital societal functions and critical infrastructures at a Swedish national level. In total 108 data sets were identified, of which 49 are deemed to be relevant for analyses at the national level, 54 at the regional level and 37 at the local level. Although of high usefulness fo
Inflammatory responses to acute stimuli are proposed to regulate sleep, but the relationship between chronic inflammation and habitual sleep duration is elusive. Here, we study this relation using genetically predicted level of chronic inflammation, indexed by CRP and IL6 signaling, and self-reported sleep duration. By Mendelian randomization analysis, we show that elevated CRP level within <10 mg
The most prevailing hypothesis regarding mechanisms behind specific language impairment today is the hypothesis of general limitations of processing capacity. Such an hypothesis can hardly be tested by available language assessment tools, especially not by instruments in use for clinical assessment of the lexical-semantic domain in children. Reduced naming speed is by some researchers considered a
Hirshfeld atom refinement (HAR) provides a more realistic interpretation of crystallographic data than the standard independent atom model (IAM) by using aspherical atomic form factors derived from quantum mechanical (QM) calculations. With this aspherical description, it is possible to obtain improved atomic positions, atomic displacement parameters and correct bond lengths even for hydrogen atom
BACKGROUND AND OBJECTIVES: Reproductive-aged women are at an increased risk of developing iron deficiency (ID). We aimed to develop a non-invasive screening tool to identify ID in women and assess the acceptability of screening.STUDY DESIGN AND METHODS: We screened women (age 18-49 years) in the community of Western Australia.PRIMARY OUTCOME: acceptability of screening, assessed by the feasibility
Context. Despite the ever-increasing number of known exoplanets, no uncontested detections have been made of their satellites, known as exomoons. Aims. The quest to find exomoons is at the forefront of exoplanetary sciences. Certain space-born instruments are thought to be suitable for this purpose. We show the progress made with the CHaracterising ExOPlanets Satellite (CHEOPS) in this field using
Co-pathology is a common feature of neurodegenerative diseases that complicates diagnosis, treatment and clinical management. However, sensitive, specific and scalable biomarkers for in vivo pathological diagnosis are not available for most neurodegenerative neuropathologies. Here, we present ProtAIDe-Dx, a deep joint-learning model trained on 17,170 patients and controls that uses plasma proteomi
Building materials account for a high percentage of the non-land cost of self-help housing. Few studies, however, have examined the use of building materials by self-help builders and the practicalities of producing and distributing the materials in an alternative manner. This paper discusses the nature of construction by self-help in the intermediate-sized Colombian city of Pereira, focusing in p
The current framing of AI-driven technologies situates them as solutions to a looming care crisis. However, this overlooks informal caregivers' key role to current State budgetary deficits impacting healthcare services happening in Europe. As States increasingly rely on informal caregivers to provide care before the necessary involvement of healthcare services, there is already well-established re
The potential to source thermal energy from buried infrastructure such as tunnels and metro stations may offer significant potential to reduce the carbon dioxide emissions of heating and cooling, and reduce the costs associated with dedicated drilling for traditional ground-sourced systems. However, this remains a niche approach with few commercial schemes globally, partly due to high initial cost
This article is based on anthropological fieldwork undertaken at two elite universities in Beijing. It addresses the paradoxical situation of the many instances of suicide among Chinese elite university students in Beijing, which constitute a public secret. The pressure of education weighs heavily on the shoulders of China’s only child in each family, known as the generation of little emperors and
Cognitive behavioral therapy (CBT) is a well-established, evidence-based treatment for common mental disorders such as depression, anxiety disorders, and obsessive-compulsive disorder (OCD). However, treatment outcomes vary widely, and a substantial proportion of patients do not achieve sufficient improvement. Robust predictors of individual differences in symptom change are currently lacking. Gen
We describe the history, construction, and use of a portable walk-in wader trap (i.e., modified Ottenby trap) designed to be used in field expedition conditions. It is rectangular-shaped, 120 x 41 x 32 cm when operational, weighs between 1.5 and 2 kg (depending on materials used) and can be folded flat for easy transportation. It consists of several metal frames filled with fishing net, and has a
Popular Abstract in Swedish Syftet med avhandlingen var att studera eventuella skillnader vad gäller förlåtelse beroende av attachmentmönster. Deltagare i studien (N = 359) var gymnasieelever från Malmö. De instrument som användes var Brennan, Clark and Shaver's Experiences in Close Relationships (ECR) och Enright Forgiveness Inventory (EFI). Resultatet visade att ECR:s avoidance dimension var negThe purpose of this dissertation was to study potential differences in forgiveness depending on attachment-styles. The sample (N = 359) consisted of upper secondary school students from Sweden. The instruments that were used after translation and standardization were: Brennan, Clark and Shaver's Experiences in Close Relationships (ECR) and Enright Forgiveness Inventory (EFI). The results showed th
Neutral Higgs bosons of the Standard Model (SM) and the Minimal Supersymmetric Standard Model (MSSM) were searched for in the data collected in 1999 by the DELPHI experiment at centre-of-mass energies between 191.6 and 201.7 GeV with a total integrated luminosity of 228 pb(-1). These analyses, in combination with our results at lower energies, set 95% confidence level lower mass bounds on the Stan
Strain Comamonas testosteroni TI, capable of degrading the nonionic surfactant (NIS) nonylphenolethoxylate (OP-10), was used for constructing a pilot cellular biosensor. The lower NIS detection limit for the biosensor was 0.25 mg/l. We studied the substrate specificity of the biosensor with respect to a wide range of organic compounds: surfactants, polyaromatic compounds (PAC), carbohydrates, alco
