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https://www.iiiee.lu.se/sites/iiiee.lu.se/files/course_syllabus_imen44_cem.pdf - 2026-07-11

Objective. To establish a high-throughput system for testing the ability of drugs or monoclonal antibodies to reduce the in vitro formation of cystatin C dimers to identify substances potentially useful for treatment of patients with hereditary cystatin C amyloid angiopathy (HCCAA). Methods. Various combinations of incubation temperature, time period, guanidinium chloride concentration and concent

Fission track analysis (FTA) was developed to be applied to ultra-low levels of 239Pu in bioassay samples. An analytical protocol was established for the FTA processing. The detection limit was determined to 1.5 µBq and the calibration constant was 24 fission fragments per µBq 239Pu. Naturally occuring nuclides of thorium and uranium, present in biological and environmental samples, did not interf

Several transcripts have been claimed to be clinically valuable for detecting minimal disease in neuroblastoma, but they have not been prospectively compared in a standardized manner. Tyrosine hydroxylase (TH), dopa decarboxylase (DDC) and GD2 synthase (GD2S) mRNAs were analyzed in 554 blood (PB) and bone marrow (BM) samples from 58 children with neuroblastoma. Samples from 44 children with other

OBJECTIVE: To define a minimum Standard Set of outcome measures and case-mix factors for monitoring, comparing, and improving healthcare for patients with clinically diagnosed hip or knee osteoarthritis (OA) with a focus on defining the outcomes that matter most to patients. METHODS: An international Working Group (WG) of patients, arthroplasty register experts, orthopedic surgeons, primary care

BACKGROUND: Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health system performance, help to prioritise investments in research and development, and monitor progress toward the Sustainable Development Goals (SDGs). We aimed to provide updated HALE a

This is a qualitative study with the subject; intimate partner violence. The study is based on an assessment manual from Socialstyrelsen named Manual för FREDA Standardiserade bedömningsmetoder för socialtjänstens arbete mot våld i nära relationer. The purpose of the FREDA-manual is to investigate and identify violence in intimate relationships and the purpose of this study focus on investigating

A simple and fast method is presented to be used for example in studies on the relationship between serum levels of persistent organic pollutants and type 2 diabetes mellitus. Method is based on liquid-liquid extraction and gas chromatography coupled with high.-resolution mass spectrometry. In the sample pretreatment special attention was paid to minimize the number of sample manipulation steps an

Non-human animals are often excluded from contemporary political theories, much to their detriment in terms of welfare and protection. The ‘political turn’ is a subset of animal ethicists concerned with moving beyond motivating moral status and instead discussing the politics of a shared human-animal society. This thesis evaluates Philip Pettit’s neo-republicanism as a theoretical framework for a

The prevalence of obesity among children and adolescents is on the rise. The majority of overweight or obese children are treated by primary health care providers including paediatricians, family practitioners, dieticians, nurses, and school health services - and not by specialists. The majority of obese children have no underlying medical disorder causing their obesity yet a significant proportio

Air pollution has increasingly been the focus of management and policy efforts since the early 1950s. Networks of monitoring stations for data to inform, create, focus, assess and improve air pollution management and policy. However, monitoring systems can become disconnected from air quality management and policy without analysis and interpretation to bridge the divide. This thesis develops a met

The choice of society – who is to vote? Opportunities to participation in the general elections for people with intellectual disabilities related to the Swedish national objective of an accessible society for all citizens The aim of this study is twofold; first to examine how Swedish government authorities and other relevant actors in the society regard the accessibility of general elections for

Background Being born small for gestational age (SGA) or large for gestational age (LGA) has short and long term metabolic consequences. There is a growing interest in the extent to which body composition, both in the short and the long term, differs in infants born at the extremes of these birth weights. Methods Body composition in 25 SGA and 25 LGA infants were assessed during the first days of

A search for neutral Higgs bosons of the minimal supersymmetric standard model (MSSM) and for a heavneutral Z′ boson is performed using a data sample corresponding to an integrated luminosity of 3.2 fb- 1 from proton–proton collisions at s=13 TeV recorded by the ATLAS detector at the LHC. The heavy resonance is assumed to decay to a τ+τ- pair with at least one τ lepton decaying to final states wit