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Purpose: The hippocampus is affected by tau pathology early in Alzheimer's disease (AD) development. Accurate quantification of hippocampal tau signal using the tau-PET tracer 18F-flortaucipir is complicated, however, by off-target binding in the adjacent choroid plexus. We here present a new method for compensating for this off-target choroid plexus signal. Methods: As off-target binding in the c
Anaerobic digestion of food waste is an attractive and increasingly popular technology within waste management and energy recovery. A better understanding of the microbiology associated with anaerobic digestion of food waste will provide new insight into the operational conditions required for optimizing this process, as well as its potential for utilisation in co-digestion systems. Eighteen full-
A detailed study has been made of the method for labeling streptokinase with 99Tc(m) in order to get a radioactive indicator for rapid scintigraphic visualization of thrombi and emboli. The best method found for preparing 99Tc(m) streptokinase was by reducing 99Tc(m) pertechnetate with 2 μmole SnCl2 at pH 0.7 and then adding 50,000 to 75,000 IU of streptokinase at a final pH of about 2. After 1 hr
Objective: Predicting treatment response and disease progression in rheumatoid arthritis (RA) remains an elusive endeavour. Identifying subgroups of patients with similar progression is essential for understanding what hinders improvement. However, this cannot be achieved with response criteria based on current versus previous Disease Activity Scores, as they lack the time component. We propose a
We analyse the performance of risk reduction strategies for terrorist attacks with Improvised Explosive Devices (IEDs) for large governmental building structures in terms of cost-efficiency, significance and effectiveness accounting for life safety in conjunction with societal preferences and capabilities. The approach builds upon an extended Bayesian pre-posterior decision analysis and the princi
This article introduces an approach and framework for the quantification of the value of structural health monitoring (SHM) in the context of the structural risk and integrity management for systems. The quantification of the value of SHM builds upon the Bayesian decision and utility theory, which facilitates the assessment of the value of information associated with SHM. The principal approach fo
The provision and administration of high quality urban public green spaces intertwines issues of planning, design, management and maintenance with governance. The benefits of such spaces are often tied to social justice, public health and recreation, biodiversity and helping cities to deal with climate change. International policies and changes in public administration have encouraged user partici
Photonic materials for high-temperature applications need to withstand temperatures usually higher than 1000 °C, whilst keeping their function. When exposed to high temperatures, such nanostructured materials are prone to detrimental morphological changes, however the structure evolution pathway of photonic materials and its correlation with the loss of material's function is not yet fully underst
Long-term instability in multiplanet exosystems is a crucial consideration when confirming putative candidates, analysing exoplanet populations, constraining the age of exosystems and identifying the sources of white dwarf pollution. Two planets that are Hill stable are separated by a wide-enough distance to ensure that they will never collide. However, Hill-stable planetary systems may eventually
Several serious problems such as material durability and fouling in the High Temperature Heat Exchanger (HTEH) for Externally Fired Micro Gas Turbines (EFMGT) cause the low thermal efficiency. In this study for increasing the thermal efficiency, a duct around a cylindrical fixed bed combustor which burns wood pellets is proposed and two different designs, empty and porous material filled, are inve
We describe an automatic system for pose-estimation from a single image in a city scene. Each building has a model consisting of a number of parallel planes associated with it. The homographies for the best match of the planes to the image is estimated automatically for each of the possible buildings. We show how the estimation of the homographies can be done effectively by reducing the search spa
Accident prediction models are often used to predict the number of accidents on segments and at intersections in the road network. Most often the models are developed for a total number of crashes for the facility, or crashes by severity. However, the frequency and severity of crashes of different types can be expected to vary with regards to the underlying phenomena that cause them to occur. To b
Ultra-wideband (UWB) communication is a potential technique for future high-speed networks. In this paper, we investigate low complexity signal detection approaches for OFDM based UWB systems. In particular, we develop practical approaches for channel estimation and interference suppression. Computer simulation results show that these techniques can be effectively used in OFDM based UWB systems fo
