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OBJECTIVES: To describe clinical characteristics and prognosis related to heart failure (HF) phenotypes in a community-based population by applying a novel algorithm to obtain ejection fractions (EF) from electronic medical records. DESIGN: Retrospective population-based cohort study. SETTING: Data were collected for all patients with HF in Southwest Sweden. The region consists of three acute care
We report the discovery of TOI-1268b, a transiting Saturn-mass planet from the TESS space mission. With an age of less than 1 Gyr, derived from various age indicators, TOI-1268b is the youngest Saturn-mass planet known to date; it contributes to the small sample of well-characterised young planets. It has an orbital period of P = 8.1577080 ± 0.0000044 days, and transits an early K-dwarf star with
This study sets out to gain a better understanding of the workings of ancient polytheism by exploring one of its fundamental modus operandi: the cohabitation of gods in sanctuaries. Cohabitation is broadly understood as the permanent or temporary sharing of sacred precincts, cultic buildings, and sacrificial structures by two or more deities, rendered present through their effigies, or merely pres
PURPOSE: Galectin-3, a β-galactoside-binding lectin, plays a key role in several cellular pathways involved in chronic inflammation, heart disease and cancer. GB1211 is an orally bioavailable galectin-3 inhibitor, developed to be systemically active. We report safety and pharmacokinetics (PK) of GB1211 in healthy participants.METHODS: This phase 1, double-blind, placebo-controlled, first-in-human
"Storsjöodjuret”, eller “The Great Lake Monster”, är ett undflyende fenomen i sjön Storsjön, belägen i landskapet Jämtland i norra Sverige. Denna avhandling i ämnet humanekologi undersöker hur det sammankopplingar av det sociala, det kulturella, det historiska och det lokala påverkar formandet av detta svenska kryptid, eller “dolda djur”. Syftet med studien är att visa hur detta vetenskapligt ännuStorsjöodjuret, or The Great Lake Monster, is an elusive phenomenon in lake Storsjön, situated in the province of Jämtland in Northern Sweden. This dissertation in Human Ecology investigates how the intricate web of the social, the cultural, the historical, and the local influence the shaping of this Swedish cryptid, or “hidden animal”. The purpose of the study is to demonstrate how this scientif
Syndromic testing for lower respiratory tract infections with BioFire® FilmArray® Pneumonia Panel Plus (BF) detects 27 pathogens with a turn-around-time of one hour. We compared the performance of BF with culture. Samples from 298 hospitalized patients with suspected pneumonia routinely sent for culture were also analyzed using BF. Retrospectively, patients were clinically categorized as having "p
BackgroundWe aimed to fill the gaps of knowledge concerning incidence rates and temporal trend, clinical features and risk factors for death for M. morganii bloodstream infections in south Sweden.MethodsThis was an observational, population-based study including all patients with at least one blood culture positive for Morganella morganii between 2013-2023 in Skåne, south Sweden.ResultsA total of
A naturalistic view should make us appreciate the rich possibilities of nature. This naturalistic point of departure, as formulated by Willem B. Drees, invites reflection on the relationship between nature and spirituality. Today, the concept of sustainability occupies a key role in what has come to be the greatest challenge ever that humankind has faced together at the same moment in history. Usu
Metal oxide nanoparticles are widely used in catalysis, photovoltaics, and gas sensing, where surface structure and oxidation state strongly influence performance. This work investigates how carrier gas composition, combined with in-flight heating, can be used to control the surface properties of metal oxide nanoparticles generated via the gas-phase method, spark ablation. Sn, Zn, and Al nanoparti
In 2025, the Swedish Film Institute announced that it would minimise the funding of films deemed “international” to safeguard “Swedish” perspectives. Triggered by the success of a series of Swedish co-productions shot elsewhere, in other languages, by filmmakers of mixed or diasporic background, said shift in film policy is symptomatic of a wider Nationalist turn in Swedish politics, and the cultu
BACKGROUND: Secondary peritonitis caused by gastrointestinal perforation is associated with significant morbidity and mortality. Effective management includes surgical source control, antibiotic therapy, and intensive resuscitation. The choice between primary abdominal closure (PAC) and vacuum-assisted closure (VAC) in the management of secondary peritonitis remains a subject of debate.METHODS: Th
The aim of this thesis is to explore the job satisfaction of librarians and try to nuance stereotypes, which the public has and which still exist in massmedia concerning librarians and their work. The study is qualitative and based mainly on semistructured interviews with ten libraries born between 1937s and 1973s of which eight are women and two men. Furthermore, I have divided them into two grou
Sammanfattning Den här uppsatsen behandlar den höga organisationsgraden som vi har i Sverige idag. Huvudsyftet är att ge ett svar på varför organisationsgraden är så hög. Syftet är också att undersöka hur fackföreningsrörelsen kommer att utvecklas i framtiden. Uppsatsen inleds med en redogörelse av faktorer som bidragit till den höga organisationsgrad vi åtnjuter idag. Fackföreningarnas struktur b
Despite decades of research on the pathophysiology of depression, the development of new therapeutic interventions has been slow, and no biomarkers of treatment response have been clinically implemented. Several lines of evidence suggest that the clinical and biological heterogeneity among patients with major depressive disorder (MDD) has hampered progress in this field. MDD with low-grade inflamm
Recombinant human bone morphogenetic protein-2 (rhBMP-2) has been FDA-approved for lumbar fusion, but supraphysiologic initial burst release due to suboptimal carrier and late excess bone resorption caused by osteoclast activation have limited its clinical usage. One strategy to mitigate the pro-osteoclast side effect of rhBMP-2 is to give systemic bisphosphonates, but it presents challenges with
The overall aim of this thesis was to investigate parents’ experiences and satisfaction with family-centered care (FCC)when their child was cared for at a pediatric intensive care unit (PICU). To obtain a deeper understanding of parents’experiences and satisfaction, two qualitative studies were conducted (Papers I and III). For Paper I, 10 individualinterviews were conducted two years after their
The addition of polypropylene (PP) fibres has been shown to reduce the fire spalling propensity of concrete. When including this type of fibres in the concrete, the concrete mix becomes less robust, and small deviations in the constitutes change the workability and properties of the concrete. So, from a manufacturing perspective as small dosages as possible of PP fibres are desirable. Very few lar
Metal-assisted chemical etching (MACE) is a cheap and scalable method that is commonly used to obtain silicon nano- or microwires but lacks spatial control. Herein, we present a synthesis method for producing vertical and highly periodic silicon microwires, using displacement Talbot lithography before wet etching with MACE. The functionalized periodic silicon microwires show 65% higher PEC perform
There are likely many undiscovered impact structures on Earth, but several challenges prevent their detection, including possible concealment beneath large ice sheets. In recent years, geophysical, geochemical, and microphysical evidence has mounted for a ca. 58 Ma impact structure under the Hiawatha Glacier, northwest Greenland. Here, we report evidence for a second, much older hypervelocity impa
One of the major research goals in ecology is to understand predator–prey interactions. However, our understanding of how prey express phenotypic plasticity in response to co-occurring multiple predators is limited in many systems. Here, we use the rotifer Brachionus calyciflorus as model organism to test how prey responds to co-occurring predators through a series of related experiments. Firstly,
