Filetype
Purpose: Yttrium-90 (Y-90) is one of the most commonly used radionuclides in targeted radionuclide therapy (TRT). Since it decays with essentially no gamma photon emissions, surrogate radionuclides (e.g., In-111) or imaging agents (e.g., Tc-99m MAA) are typically used for treatment planning. It would, however, be useful to image Y-90 directly in order to confirm that the distributions measured wit
Based upon earlier experimental work by our group, we have started a human immuno-gene therapy study. The goal is to study the effects of immunisation with autologous tumour cells expressing gene sequences for human interferon-gamma For more than two decades we have sought for efficient treatment against malignant gliomas. Our most successful treatment in the animal models is immuno-gene therapy w
Osteoarthritis of the metacarpo/metatarsophalangeal joints is one of the major causes of poor performance in horses. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) may be a useful technique for noninvasively quantifying articular cartilage damage in horses. The purpose of this study was to describe dGEMRIC characteristics of the distal metacarpus3/metatarsus3 (Mc3/Mt
In vivo dosimetry of IMRT from Copenhagen University Hospital
The VIVE lighthouse system is evaluated for indoor positioning of micro unmanned aerialcvehicles (MUAVs). A detailed mathematical analysis is provided, including a Cramer-Raocbound derivation and performance analysis of the MUAV state estimate. The lighthousecmeasurements are fused with inertial measurements in a multiplicative extended Kalmanfilter (MEKF). We consider two implementations, one w
Inconel 718 is a Ni-based superalloy that can perform excellently at elevated temperatures. However, surface and subsurface damages in the form of microstructural and property changes and tensile residual stresses are common in a machined Inconel 718 component because of its poor machinability. Such damages have a significant influence on performance and the life time of the part. To characterise Inconel 718 is a Ni-based superalloy that can perform excellently at elevated temperatures. However, surface and subsurface damages in the form of microstructural and property changes and tensile residual stresses are common in a machined Inconel 718 component because of its poor machinability. Such damages have a significant influence on performance and the life time of the part. To characterise
Internal mixing on the giant branch is an important process which affects the evolution of stars and the chemical evolution of the galaxy. While several mechanisms have been proposed to explain this mixing, better empirical constraints are necessary. Here, we use [C/N] abundances in 26,097 evolved stars from the SDSS-IV/APOGEE-2 Data Release 14 to trace mixing and extra mixing in old field giants
Introduction: Under-dosing is a recognized problem with current nicotine replacement therapy (NRT). Therefore, a new 6mg nicotine gum has been developed. To compare the nicotine uptake from the 6mg gum versus currently available NRT products, two pharmacokinetic studies were performed.Methods: In one randomized crossover study, 44 healthy adult smokers received single doses of 6, 4, and 2mg nicoti
Ashbya gossypii is a homothallic, flavinogenic, filamentous ascomycete that starts overproduction of riboflavin and fragments its mycelium quantitatively into spore producing sporangia at the end of a growth phase. Mating is not required for sporulation and the standard homothallic laboratory strain is a MATa strain. Here we show that ectopic expression of Saccharomyces cerevisiae MATα2 in A. goss
BACKGROUND: Prognostication of recovery in patients who are unconscious following cardiac arrest can be guided by concentrations of brain injury biomarkers in the blood. The optimal biomarker and cutoff concentrations for the prediction of outcome remain unknown. In this study, we aimed to evaluate which biomarker of brain injury is most accurate for predicting functional outcome after cardiac arr
Objectives Early detection of neurosensory injury among workers exposed to hand-arm vibration is crucial. The aim of our study was to evaluate the diagnostic test performance of clinical point-of-care testing using a tuning fork and temperature rollers in relation to vibrotactile and thermal quantitative sensory testing. Methods We recruited 225 vibration-exposed workers who underwent clinical poi
Online engagement with criminal cases is often interpreted in either punitive or crowdsourcing terms, but interactionist and ethnomethodological analyses can disclose other and more fundamental aspects. This chapter looks closely at a particular practice among posters on the Swedish platform Flashback: that of summing up the discussion ‘so far’. To sum up is a delicate and vulnerable act of rhetorOnline engagement with criminal cases is often interpreted in either punitive or crowdsourcing terms, but interactionist and ethnomethodological analyses can disclose other and more fundamental aspects. This chapter looks closely at a particular practice among posters on the Swedish platform Flashback: that of summing up the discussion ‘so far’. To sum up is a delicate and vulnerable act of rhetor
Across the scholarly and journalistic literature, an increasing sense of future uncertainty and prevailing sense of dread is being narrated. This unsettling sense of futurelessness seems to cut across scales in that globally unfolding menaces also shape lived experience locally in specific sites, where global risks intersect with local hazardousness of place. In this chapter, we reflect on how a s
BackgroundImpact of rectal tumour location on risk of lymph node metastases (LNM) and recurrence in early RC is poorly studied and elusive. Tumour location as a prognostic factor may contribute to optimise management of early RC in the future. The aim of this study was to investigate rectal tumour location as an independent predictor of oncologic outcome in early rectal cancer (RC).MethodsRetrospeBACKGROUND: Impact of rectal tumour location on risk of lymph node metastases (LNM) and recurrence in early RC is poorly studied and elusive. Tumour location as a prognostic factor may contribute to optimise management of early RC in the future. The aim of this study was to investigate rectal tumour location as an independent predictor of oncologic outcome in early rectal cancer (RC).METHODS: Retr
AIMS: To investigate the individual characteristics, causes and circumstances around deaths in stimulant use, and to examine how individuals who died with stimulants in their body differ from individuals who died with opioids in their body.METHODS: This study includes individuals who died during the years 2000-2018 and underwent a forensic autopsy at Forensic Medicine in Lund, Skåne County, Sweden
Cities today globally face significant problems in the context of the climate crisis. Firstly, in terms of resilience in enduring future challenges – urban heat islands, increasingly frequent flooding, supply chain disruptions, sea level rise among others. Secondly, in terms of contributing to said crisis, through carbon emissions, the erosion of biodiversity through sprawl, overconsumption, and c
The fall of Yugoslavia in the 1990s led to a series of political upheavals, culminating in the 1992 referendum in Bosnia and Herzegovina. This referendum triggered the Bosnian War, which was finally ended by the Dayton Peace Agreement signed on December 14, 1995. The Dayton Peace Agreement aimed to stabilize the country by establishing a power-sharing arrangement among its three ethnic groups - Bo
A tender offer is basically a technique to attain corporate control. It could be characterised as an offer to acquire shares of a company, whose shares are not closely held, addressed to the general body of shareholders, usually at a premium, with a view to obtaining at least sufficient shares to give the offeror voting control of the company. In the United States tender offers are governed by the
