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Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis

To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc

Comparison of Surface Properties of Human IgA, IgE, IgG and IgM Antibodies with Identical and Different Specificities

In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha

Polygenic pathways shape white matter vulnerability to Alzheimer’s disease-related pathophysiological changes

Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei

Methane and carbon dioxide fluxes over a lake : Comparison between eddy covariance, floating chambers and boundary layer method

Freshwaters bring a notable contribution to the global carbon budget by emitting both carbon dioxide (CO2) and methane (CH4) to the atmosphere. Global estimates of freshwater emissions traditionally use a wind-speed-based gas transfer velocity, kCC (introduced by Cole and Caraco, 1998), for calculating diffusive flux with the boundary layer method (BLM). We compared CH4 and CO2 fluxes from BLM wit

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Master’s Dissertation Structural Mechanics INFLUENCE OF ANNUAL RING ORIENTATION ON COMPRESSION STRENGTH PERPENDICULAR TO GRAIN IN GLULAM Report TV SM -5203 PH ILIP W A LLIN IN FLU EN C E O F A N N U A L R IN G O R IEN TA TIO N O N C O M PR ESSIO N STR EN G TH PER PEN D IC U LA R TO G R A IN IN G LU LA M PHILIP WALLIN 5203HO.indd 15203HO.indd 1 2015-06-23 15:03:362015-06-23 15:03:36 DEPARTMENT OF C

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5203.pdf - 2026-05-07

Calculation and Measurement Methods for the Performance of Solar Collectors. Models of Flat Plate Collectors, Transparent Insulation and Efficiency Factors.

Popular Abstract in Swedish Denna avhandling handlar om modeller för plana solfångare, transparent isolering och verkningsgradsfaktorer. En ekvation för energiutbytet från en glasad plan solfångare härleds genom att modellera verkningsgradsfaktorn, F´, som en summa av en konstant och en temperaturberoende del. Ett alternativt sätt att testa en plan solfångare, baserat på denna modell, föreslås. EThis thesis deals with models of flat plate collectors, transparent insulation and efficiency factors. An equation for the energy output from a glazed flat plate collector is derived by modelling the collector efficiency factor, F´ as the sum of a constant and a temperature dependent part. An alternative way of testing a flat plate collector, based on this model, is suggested. A complete set of a

The IgG-degrading enzyme of Streptococcus pyogenes causes rapid clearance of anti-glomerular basement membrane antibodies in patients with refractory anti-glomerular basement membrane disease

In anti-glomerular basement membrane (anti-GBM) disease, IgG class autoantibodies induce rapidly progressive glomerulonephritis. Regrettably, many patients are diagnosed at a late stage when even intensive conventional treatment fails to restore renal function The endopeptidase IdeS (Immunoglobulin G degrading enzyme of Streptococcus pyogenes) (imliflidase) rapidly cleaves all human IgG subclasses

Arsine, Stibine and Phosphine Derivatives of [Fe2(CO)6(μ-bdt)] (bdt = Benzenedithiolate) : Syntheses, Structures and Spectroscopic and Electrocatalytic Studies

The reactivity of the benzenedithiolate (bdt)-bridged complex [Fe2(CO)6(µ-bdt)] with arsine, stibine and phosphine ligands has been studied. The new mono- and disubstituted complexes [Fe2(CO)5(EPh3)(µ-bdt)] (E = As, 1; E = Sb 3) and [Fe2(CO)4(EPh3)2(µ-bdt)] (E = As, 2; E = Sb, 4) and the previously reported [Fe2(CO)4(PPh2H)2(µ-bdt)] (5) have been prepared by Me3NO-initiated carbonyl substitution r

Enhancing the Accuracy of CSI-Based Positioning in Massive MIMO Systems

Massive Multiple-Input Multiple-Output (MIMO) communication systems are being investigated intensively for positioning services. Enhancing the accuracy on these services in terms of accurate positioning of users is an important goal to improve related applications in the future. Convolutional Neural Networks (CNNs) has been proposed to infer the position of a user from Channel State Information (C

The derivation of first- and second-order backpropagation methods for fully-connected and convolutional neural networks

We introduce rigorous theory for deriving first and second order backpropagation methods for Deep Neural Networks (DNN) whilst satisfying existing theory in DNN optimization. We begin by formally defining a neural network with its respective components and state the first and second order chain rule with respect to its partial derivatives. The partial derivatives in the chain rule formula are rela

Homozygosity for the IgG2 subclass allotype G2M(n) protects against severe infection in hereditary C2 deficiency

Homozygous C2 deficiency (C2D) is the most common deficiency of the classical complement pathway in Western countries. It is mostly found in patients with autoimmune disease or susceptibility to bacterial infections and in healthy persons. We wished to assess to what extent other immunological factors might explain differences of susceptibility to infections in C2D. For this reason, 44 Swedish pat

Jama lugar 2023 oi 230100 1695046175.41487

SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood Marija Lugar, MSc; Anne Eugster, PhD; Peter Achenbach, MD; Thekla von dem Berge, MD; Reinhard Berner, MD; Rachel E. J. Besser, MD; Kristina Casteels, MD; Helena Elding Larsson, MD; Gita Gemulla, MD; Olga Kordonouri, MD; Annett Lindner; Markus L

https://www.gppad.lu.se/sites/gppad.lu.se/files/2023-10/jama_lugar_2023_oi_230100_1695046175.41487.pdf - 2026-05-08

Jama lugar 2023 oi 230100 1695046175.41487

SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood Marija Lugar, MSc; Anne Eugster, PhD; Peter Achenbach, MD; Thekla von dem Berge, MD; Reinhard Berner, MD; Rachel E. J. Besser, MD; Kristina Casteels, MD; Helena Elding Larsson, MD; Gita Gemulla, MD; Olga Kordonouri, MD; Annett Lindner; Markus Lundgren, MD; Denise Müller, BSc; Mariusz Oltarzewski, PhD; Anne Rochtus, MD; M

https://www.gppad.lu.se/sites/gppad.lu.se/files/2024-01/jama_lugar_2023_oi_230100_1695046175.41487.pdf - 2026-05-08

Ana Rebordão

Sometimes it ends with a kiss Ana Rebordão creates staged environments in which she always plays the central figure, shifting between roles. Her latest piece, Sometimes it ends with a kiss, reflects on power relations within family structures. Through absurd, enigmatic performances, she evokes a sense of trauma and gives a sharp voice to silent female characters. The work shows women speaking to t

https://www.iac.lu.se/ana-rebordao - 2026-05-07

Surface proteins of pathogenic streptococci

Popular Abstract in Swedish Grupp B streptokocker (GBS; Streptococcus agalactiae) är den vanligaste orsaken till livs-hotande infektioner hos nyfödda barn. Enbart i USA orsakar GBS ~10 000 fall av meningit (hjärnhinneinflammation), pneumoni (lunginflammation) och sepsis (blodförgiftning) varje år. Infektionerna har hög dödlighet och en stor del av de barn som överlever infektionerna får bestående Streptococcus pyogenes (group A streptococcus) and the group B streptococcus (GBS) are two important human pathogens that cause different types of diseases and express different surface structures implicated in virulence. This thesis focuses on several surface proteins expressed by these pathogens, analyzing the biological function of these proteins and their ability to elicit protective immunity.