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Multisensory stimulation improves functional recovery and resting-state functional connectivity in the mouse brain after stroke
Stroke causes direct structural damage to local brain networks and indirect functional damage to distant brain regions. Neuroplasticity after stroke involves molecular changes within perilesional tissue that can be influenced by regions functionally connected to the site of injury. Spontaneous functional recovery can be enhanced by rehabilitative strategies, which provides experience-driven cell s
A critical review on the application of the National Sanitation Foundation Water Quality Index
Role of hexaminolevulinate-guided fluorescence cystoscopy in bladder cancer: critical analysis of the latest data and European guidance
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Measuring Antibody Orientation at the Bacterial Surface
The Minerva of the North and her medals : Iconographic strategies of Queen Christina’s reign in Sweden
Novel peptide ligand with high binding capacity for antibody purification
Small synthetic ligands for protein purification have become increasingly interesting with the growing need for cheap chromatographic materials for protein purification and especially for the purification of monoclonal antibodies (mAbs). Today, Protein A-based chromatographic resins are the most commonly used capture step in mAb down stream processing; however, the use of Protein A chromatography
Functional C1-inhibitor diagnostics in hereditary angioedema: Assay evaluation and recommendations
Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of potentially life-threatening angioedema. The most widespread underlying genetic deficiency is a heterozygous deficiency of the serine protease inhibitor Cl esterase inhibitor (C1-Inh). In addition to low C4 levels, the most important laboratory parameter for correct diagnosis of HAE or angioedema du
A comparative study between the two patch-test systems Finn chambers and Finn chambers AQUA
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"Vi kanske kommer igen, om det låser sig" : Kvinnors och mäns möte med familjerådgivning.
Popular Abstract in Swedish Kring familjeproblematiken och för behandlingen av familjekonflikter har det svenska samhället organiserat olika sociala verksamheter som traditionellt regleras av Socialtjänstlagen. Familjerådgivningen är en av dessa verksamheter och definieras som en psykoterapeutisk behandling, till vilken en eller båda parter vänder sig oftast på frivillig basis när de upplever att
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Endogenous hormones, androgen receptor CAG repeat length and fluid cognition in middle-aged and older men: results from the European Male Ageing Study
Objective: Data remain divergent regarding the activational effects of endogenous hormones on adult cognitive function. We examined the association between cognition, hormones and androgen receptor (AR) CAG repeat length in a large cohort of men. Design: Community-based, cross-sectional study of 3369 men aged 40-79 years. Methods: Cognition tests were the Rey-Osterrieth Complex Figure, Camden Topo
Longitudinal functional connectivity during rest and task is differentially related to Alzheimer’s pathology and episodic memory in older adults
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A comparison of different orthogonal techniques for the investigation of the conformational stability of NIST mAb in liquid formulations
Antikroppar har ett brett användningsområde med stor potential men det är svårt att skapa stabila lösningar. Den strukturella stabiliteten är en viktig faktor när man väljer läkemedelskandidater, och i de tidiga utvecklingsstadierna görs prediktiva undersökningar för att ta reda på varje kandidats stabilitet och utvecklings-potential. Därmed är det av största intresse att utvärdera hur antikropparA great challenge during early development of medicinal antibodies is to determine the stability of the candidates. This is required to be able to select the candidates with the greatest developability. The stability of the candidates can be estimated using different orthogonal techniques and the aim of this investigation was thus to use orthogonal techniques for the investigation of conformationa
