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Complement C2 deficiency (C2D) is associated with immunological diseases and increased susceptibility to invasive infections caused by encapsulated bacteria such as Neisseria menigitidis. In this study we evaluate the immunogenicity of vaccination against N. menigitidis in C2D. C2D patients (n=22) and controls (n=52) were given a tetravalent meningococcal polysaccharide vaccine. Serum bactericidal

Objective. Antileukoproteinase (ALP) is a physiologic inhibitor of granulocytic serine proteases. The present study was undertaken to investigate its therapeutic benefit in an antibody-transfer model of erosive polyarthritis and to elucidate its potential to interfere with immune complex-dependent inflammatory pathways. Methods. Arthritis development was induced in male (BALB/c x B10.Q)F-1 mice by

Transplantation of allogeneic embryonic neural tissue is a potential treatment for patients with Parkinson's and Huntington's diseases. The supply of human donor tissue is limited, and alternatives such as the use of animal (e.g., porcine) donor tissue are currently being evaluated. Before porcine grafts can be used clinically, strategies to prevent neural xenograft rejection must be developed. Kn

Background: Nigeria is a major contributor to the global malaria burden. The genetic diversity of malaria parasite populations as well as antibody responses of individuals in affected areas against antigens of the parasite can reveal the transmission intensity, a key information required to control the disease. This work was carried out to determine the allelic frequency of highly polymorphic Plas

Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,

Antimicrobial peptides (AMPs) are evolutionarily ancient molecules. They are essential innate immune response molecules that protect organisms from invading pathogens. Tissue factor pathway inhibitors (TFPI-1 and TFPI-2) C-terminal derived peptides exert host defense mechanisms against microbes. Studies showed that in human plasma, C-terminal TFPI-1 and -2 derived peptides mediate bacterial killin

Människohandel för sexuella ändamål är ett växande globalt problem. I samband med pandemin har den svenska gränspolisen rapporterat in misstankar om ökad människohandel till Sverige från länder med en mer omfattande nedstängning. Offren för denna typ av exploatering är i regel unga kvinnor som är på flykt från utsatta situationer i sina hemländer. I Sverige möter de en efterfrågan på billiga sexuHuman trafficking for the purpose of sexual exploitation is a growing global issue. In connection with the pandemic, the Swedish Border Police have reported suspicions of increased human trafficking to Sweden from countries with a more extensive lock-down. The victims of this type of exploitation are usually young women fleeing vulnerable situations in their home countries. In Sweden, they meet a

Of 30 bacterial species tested 18 stimulated DNA synthesis in human blood lymphocytes. The maximum response was after 3-4 days of culture suggesting a mitogenic effect. This was confirmed by the induction of polyclonal antibody production shown by a plaque assay. Most bacterial species increased the DNA synthesis in B-enriched lymphocytes and unseparated lymphocytes but had negligible activity on

Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient

The aim of this study is to further the understanding of why dual citizenship continues to reappear in Dutch debates while dual citizenship has remained rather uncontested in Sweden for the last decade. Differences in the in which terms dual citizenship is discussed and the way dual citizenship is perceived is put forward as a possible explanation for this difference between the countries. Using L

Lägg till titel Sida 1 av 5 Beslutad i Kvalitetsnämnden för grundutbildning 2025-06-12 Litteraturlista – MULM63, Bedömning, betygsättning och Forskningens kreativa genvägar, 11,5hp • Bedömning och betygssättning Carlgren, I., Forsberg, E., & Lindberg, V. (2009). Perspektiv på den svenska skolans kunskapsdiskussion. (s. 11–39). Stockholms universitetsförlag. https://www.diva- portal.org/smash/get/d

https://www.mhm.lu.se/sites/mhm.lu.se/files/2025-06/Litteraturlista%20MULM63%20Bed%C3%B6mning,%20betygs%C3%A4ttning%20och%20Forskningens%20kreativa%20genv%C3%A4gar.pdf - 2026-05-11

This paper examines long-run and short-term dynamics of real house prices in Sweden from the first quarter in 1986 to the last quarter in 2017. To understand this, multivariate co-integration and error correction modelling approach are used. More specifically, this paper examines whether fundamental factors of demand and supply can explain the real house price development in Sweden. Evidence shows

18 maj 2026 11:00 till 12:05 | Seminarium The official Prize Lecture in honour of the Crafoord Prize Laureate 2026 in Geosciences. The Royal Swedish Academy of Sciences awarded the 2026 Crafoord Prize to Veerabhadran Ramanathan, Scripps Institution of Oceanography, University of California San Diego, USA. He has laid the foundation for our understanding of how small particles and gases that accumu

https://www.lu.se/evenemang/crafoord-prize-lecture-geosciences-2026 - 2026-05-10

The intense debate on continuity in child grammars has largely focused on the existence of Functional Categories (FCs) in early grammars despite differences in language use with adults (e.g., omissions, word order errors, lack of case marking). Simplified, the major theoretical explanations for these properties range from Maturational accounts (Radford 1990 and later) claiming an initial absence o

Checklista för uppdragsavtal Forskningsservice Sophie Hydén Picasso Finansieringsmetoder för excellens PLANERA EN AKADEMISK KARRIÄR En akademisk karriär är ofta mångfacetterad, och dess olika delar ställer krav på olika typer av egenskaper och färdigheter. Olika karriärprofiler och vägar framåt kan överlappa och kombineras, alternativt så rör man sig mer etappvis längst karriärvägen. Forskning, un

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/finansieringsmetoder-for-excellens.pdf - 2026-05-11