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Background:The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.Methods:Over half a million participants
This study aims to explore the scope of ‘knowledge-carrying’ objects in learning situations. The studyis based on a qualitative content analysis of a design project conducted in a science centre for childrenaged 7-10 years, learning about polymers and circularity. The design project is based on researchthrough design and has been an iterative process where design experiments and observations werei
Background: Allergic rhinitis often gives rise to impaired quality of life and is believed to also affect cognitive function. We aimed to examine whether cognitive functions were impaired during grass pollen season in symptomatic allergic children and to relate the degree of impairment to quality of life and biomarkers related to stress and inflammation. Methods: Forty-three grass pollen-allergic
Background Post-operative cognitive dysfunction (POCD) after non-cardiac surgery is a well known problem in some categories of patients. This study aims to evaluate the influence of auditory evoked potential (AEP)-guided anaesthesia on the requirement for anaesthetic drugs and their influence on POCD. Methods Four hundred and fifty patients aged between 18 and 92 years scheduled for ophthalmic sur
Popular Abstract in Swedish Svenska knäplastikregistret och knäledsoperation med enkammarprotes av Stefan Lewold Ledsjukdom, oftast artros, är den vanligaste kroniska åkomman hos äldre. Dess orsak är oftast inte känd och någon förebyggande behandling finns inte. Icke operativ behandling kan i tidiga stadier dämpa symptomen men då sjukdomen fortskrider får patienten allt svårare att klara sig. GenThe Swedish Knee Arthroplasty study has prospectively registered and followed knee arthroplasties done in Sweden since 1976. Demography, epidemiology and general knee prosthetic biofunction is given for 30,003 primary knee arthro-plasties and their revisions through 1992. The annual number of knee arthroplasties increased fourth fold while the relative use of Unicompartmental knee arthroplasty (UK
Room-temperature ionic liquids (RTILs) are compounds composed entirely of ions, which are liquid at temperatures below 100 degrees Celsius. Their high ionic strength and strong coupling make them useful for a number of applications, e.g. as electrolytes in supercapacitors. These properties also make them interesting subjects for theoretical research, as the canonical theories of the electrical dou
OBJECTIVESTo characterize the phenotypic presentation at diagnosis of childhood-onset primary Sjögren syndrome (SjS).METHODSThe Big Data Sjögren Project Consortium is an international, multicentre registry using worldwide data-sharing cooperative merging of pre-existing clinical SjS databases from the five continents. For this study, we selected those patients in whom the disease was diagnosed bel
Nitrate pollution in groundwater is a serious problem in many parts of the world. However, due to the diffuse and common spatially over-lapping character of potential several non-point pollution sources, it is often difficult to distinguish main nitrate sources responsible for the pollution. For this purpose, we present a novel methodology applied to groundwater for an intensely polluted area. Gro
Introduction: Detection of early arthropathy is crucial for the management of haemophilia, but data on moderate haemophilia are limited. Therefore, we evaluated joint health and treatment modalities in Nordic patients with moderate haemophilia A (MHA) and B (MHB). Aim: To explore and compare the Haemophilia Early Arthropathy Detection with Ultrasound (HEAD-US) and Haemophilia Joint Health Score (H
Nanosized spherical copper particle embedded on oxide matrix (Cunp-Cu2O/SiO2) is synthesized from a low cost chalcopyrite concentrate. The concentrate is reduced by hydrogen at 1323 K, followed by acid leaching to produce Cunp-Cu2O/SiO2. Powder X-ray diffraction confirms the formation of metallic copper as the principal phase along with oxides of silicon and copper. The weight fractions of Cu, SiO
Intracerebral transplantation of porcine embryonic dopamine-producing neurons has been suggested as a method to treat patients with Parkinson's disease. Even though the brain is an immunologically privileged site, neuronal xenografts are usually rejected within a few weeks. T cells are important for this process, but the exact cellular events leading to rejection are poorly characterized. Brain ce
Objectives To assess 2-year durability of joint contracture correction following collagenase injections for Dupuytren's disease. Design Prospective cohort study. Setting Orthopaedic Department in Sweden. Participants Patients with palpable Dupuytren's cord and active extension deficit (AED) ≥30° in the metacarpophalangeal (MCP) and/or proximal interphalangeal (PIP) joint. A surgeon injected 0.80 m
Objective: The aim of this study was to evaluate the use of intravesical treatment and cancer-specific survival of patients with primary carcinoma in situ (CIS). Materials and methods: Data acquisition was based on the Swedish National Registry of Urinary Bladder Cancer by selecting all patients with primary CIS. The analysis covered gender, age, hospital type and hospital volume. Intravesical tre
Osteonecrosis of the femoral head often results in secondary osteoarthritis of the hip joint; however, the pathologic processes underlying the destruction of articular cartilage are not fully understood. Molecular markers in the hip joint fluids were measured to examine the changes in turnover of cartilage and other joint tissues. Marker data were related to clinical, radiological, and histopathol
Type 2 diabetes is one of the world’s major challenges today. Over 400 million people around the globe are diagnosed with diabetes and the consequences to the individual patient and health care systems are significant. Diabetes is a chronic disease and the standard treatment including lifestyle changes, metformin and insulin is in many cases not effective enough. New anti-diabetic drugs have been Type 2 diabetes is one of the world’s major challenges today. Over 400 million people around the globe are diagnosed with diabetes and the consequences to the individual patient and health care systems are significant. Diabetes is a chronic disease and the standard treatment including lifestyle changes, metformin and insulin is in many cases not effective enough. New anti-diabetic drugs have been
Samples from strata spanning the Triassic-Jurassic boundary at the GSSP at Kuhjoch and at Kendlbachgraben were studied by NAA, XRF and combustion analysis to determine Ir levels and associated geochemistry. The results are compared to previously determined carbon isotope stratigraphy at these sections. Ir concentrations in the limestones of the Kössen Formation at Kuhjoch are very low (<. 10 pg/g)
Objectives To assess the association between neonatal BCG vaccination and mortality between 28 days and 3 years of age among tuberculosis (TB)-exposed and TB-unexposed children. Design Prospective cohort study. Setting Bandim Health Project runs an urban Health and Demographic Surveillance site in Guinea-Bissau with registration of mortality, vaccination status and TB cases. Participants Children
The aim of this thesis is to study the legitimacy of interventionism which is based on human rights protection. In order to provide a wide and deep presentation of this complex phenomenon, this thesis is related to liberal democracy perspectives and the wider liberal tradition. To tie this study empirically this thesis provides a case study of humanitarian intervention in Yugoslavia in 1999. By se
Abstract This is a diploma work in industrial design by Fredrik Hyltén-Cavallius. In this project my goal was to find a product that could make the ancient fire fit better into our modern homes. I started out by looking at fire related products such as stoves and barbecues on the Swedish market. Through several interviews I also looked more closely into a couple of heat related technologies such a
