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This chapter examines everyday lived experiences of individuals and groups from various creative collectives in George Town, Malaysia. The process of these articulations is explored through their everyday dwelling in this city, especially in responding to the so-called official narrative of creative city within heritage context. This chapter aims to understand how the everyday tactics of creative
Osteoarthritis (OA) constitutes a major and increasing burden on patients, health care systems and the broader society. It is estimated that around a quarter of the adult population is affected by OA in the knee and hip and that the prevalence of OA will increase over the coming decades largely due to aging and adverse life-style factors. Prevention and effective care are critical to manage the ch
Standardised data formats and data models are essential for data integration and interoperability, which in turn adds value to data by allowing its reuse in multiple contexts. For this reason, in recent years extensive efforts have been focused on standards development. When representing the built environment, 3D city models and Building Information Models are particularly relevant, and their inte
Objective:The relationship between fatigue and cognition has not been fully elucidated in children and adolescent survivors of brain tumours. The aim of the present study was to investigate the potential relationship between fatigue and cognitive impairments in these survivors, as this group is at risk for both types of deficits.Methods:Survivors of paediatric brain tumours (n = 45) underwent a ne
Streptococcus pyogenes is a major human pathogen that causes a variety of diseases ranging from mild skin and throat infections to fatal septicemia. In severe invasive infections, S. pyogenes encounters and interacts with components of the extracellular matrix (ECM), including small leucine rich-proteoglycans (SLRPs). In this study, we report a novel antimicrobial role played by SLRPs biglycan, de
The paper presents application of lean engineering methods at design process re-engineering. Lean principles are harder to implement in an one-of-a-kind production environment rather than in an environment of a serial production, where there are almost no changes during production process. There are considerable differences in value-added activities that characterize lean production on one hand an
Application of concurrent engineering (CE) to product development process (PDP) has to consider the type of production (individual, serial, mass), product complexity and level of design: original, innovative, variation and adaptive. Systematic analyses of product development processes, workflows, data and project management, in various companies, has shown that specific criteria have to be fulfill
4MOST,1 the 4m Multi-Object spectrographic Survey Telescope, is an upcoming optical, fiber-fed, MOS facility for the VISTA telescope at ESO's Cero Paranal Observatory (Chile). The preliminary design of 4MOST features 2,400 fibers split into a low-resolution (1,600 fibers, 390-900 nm, R > 5; 000) and a high-resolution channel (800 fibers, three arms, ∼20-25 nm coverage each, R > 18; 000) with an Ec
Background: Little attention has been given to the risk of cardiovascular and psychiatric comorbidities during the clinical evaluation of a suspected hematological malignancy.Methods: Based on Skåne Healthcare Register, we performed a population-based cohort study of 1,527,449 individuals residing during 2005-2014 in Skåne, Sweden. We calculated the incidence rate ratios (IRRs) of cardiovascular d
In both the Geo and BIM domains, it is widely acknowledged that the integration of geo-data and BIM-data is beneficial and a crucial step in facing the multi-disciplinary challenges of our built environment. The result of this integration - broadly termed as GeoBIM - has a range of potential uses from district study to road safety. However, from the data perspective, this integration raises the qu
We investigated the skin sensitization hazard of glyphosate, the surfactant polyethylated tallow amine (POEA) and two commercial glyphosate-containing formulations using different omics-technologies based on a human dendritic cell (DC)-like cell line. First, the GARD™skin assay, investigating changes in the expression of 200 transcripts upon cell exposure to xenobiotics, was used for skin sensitiz
Narcolepsy type 1 (NT1) is a chronic sleep disorder caused by a specific loss of hypocretin-producing neurons. The incidence of NT1 increased in Sweden, Finland and Norway following Pandemrix®-vaccination, initiated to prevent the 2009 influenza pandemic. The pathogenesis of NT1 is poorly understood, and causal links to vaccination are yet to be clarified. The strong association with Human leukocy
Background: Analysis of sialic acid (SA) metabolites in cerebrospinal fluid (CSF) is important for clinical diagnosis. In the present study, a high-performance liquid chromatography-tandem mass spectrometry (HPLC/MS/MS) method for free sialic acid (FSA) and total sialic acid (TSA) in human CSF was validated. Methods: The method utilized a simple sample-preparation procedure of protein precipitatio
This guideline aims to describe the complement system and the functions of the constituent pathways, with particular focus on primary immunodeficiencies (PIDs) and their diagnosis and management. The complement system is a crucial part of the innate immune system, with multiple membrane-bound and soluble components. There are three distinct enzymatic cascade pathways within the complement system,
Purpose: Multidisciplinary team meetings (MDTMs) are an integral component of cancer care. Increasingly, virtual MDTMs are used to grant high-quality treatment recommendations across health-care regions, which expands and develops the local MDTM team to a regional or national expert network. We investigated health professionals’ experiences from national, virtual MDTMs for rare cancer with a focus
Background: There is a growing interest in the contextual effect of neighborhood linking social capital on different health outcomes, including cancer. Aims: To examine associations between neighborhood linking social capital and incidence and mortality of prostate cancer. Method: This cohort study was based on national registers. Between 2002 and 2015, we included 1,196,563 men aged 50 years and
Background Recently there has been increased interest in a possible association between mast cell activation (MCA) disorder and postural orthostatic tachycardia syndrome (POTS). This study examined the frequency with which symptoms and laboratory findings suggesting MCA disorder occurred in patients diagnosed with POTS. Methods and Results Data were obtained from patients in whom symptoms and orth
BACKGROUND: Axillary staging via sentinel lymph node biopsy (SLNB) is performed for clinically node-negative (N0) breast cancer patients. The Skåne University Hospital (SUS) nomogram was developed to assess the possibility of omitting SLNB for patients with a low risk of nodal metastasis. Area under the receiver operating characteristic curve (AUC) was 0.74. The aim was to validate the SUS nomogra
The report includes studies on selected development topics in Central Asian countries. The purpose is to contribute insights on the role played by human capital and liberalization in four essential areas concerning sustainable development: science, foreign investment, renewables, and online presence. Methodologically, the presented studies mainly rely on the analysis of data available from interna
Studying migrants from Sweden to the United States, we provide new evidence on return migration during the Age of Mass Migration. Focusing on a sample of migrants and stayers observed in childhood, we document limited effects on income and occupational upgrading, but large effects on wealth. Male returnees held about twice as much wealth as stayers and about 40 percent more than staying brothers.
