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Introduction: Pancreatic cancer is a highly lethal disease with a close association between incidence and mortality. First-line (FL) palliative chemotherapy prolongs survival and alleviates cancer-related symptoms. However, the survival benefit of second-line (SL) treatment is uncertain, as studies fail to consistently show prolonged survival for any given SL treatment, and in the absence of progn
Trees have the potential to improve urban air quality as leaves and needles capture air pollutants from the air, but further empirical data has been requested to quantify these effects. We measured the concentration of 32 polycyclic aromatic hydrocarbons (PAHs) in leaves of pin oak (Quercus palustris) and needles of black pine (Pinus nigra) in the City of Gothenburg, Sweden, during the summer of 2
PurposeThis paper aims to explore articulations of how individuals internalise official demands on handling COVID-19 and the function of social media in this process, and further to discuss this from a human rights’ perspective.Design/methodology/approachA thematic analysis of qualitative data from an international survey on COVID-19 and social media. The analysis was inspired by Berger and Luckma
SKA Construction phase we are now in a transition phase that hopefully will prepare us for the next challenge: start building the SKA. One of the targets of this period is to evaluate the suitability of the Taranta (proper Webjive) Suite for creating engineering User Interfaces (UIs). The Taranta suite is a framework that allows the fast creation of web UIs that directly communicate with TANGO dev
A computational fluid dynamic model describing a straight channel, relevant for water removal inside a PEFC, is developed. A volume of fluid (VOF) approach is used to investigate the two-phase interface resolved flow behavior inside the gas channel including the gas diffusion layer (GDL) surface. The size and contact angle of the liquid inlet at the interface are calculated with the lattice Boltzm
Introduction and Objectives: To compare pilot cohorts of men scheduled for radical prostatectomy imaged with novel antibody conjugates: Cohort 1 (111In-J591) single photon emission tomography (SPECT) or Cohort 2 (89Zr-J591) positron emission tomorgraphy (PET).Methods: 1) Cohort 1: Eight patients with abnormal digital rectal exam and biopsy proven prostate cancer were injected intravenously with tw
Prognostic tools are an essential component of the clinical management of patients with renal cell carcinoma (RCC). Although tumour stage and grade can provide important information, they fail to consider patient- and tumour-specific biology. In this study, we set out to find a novel molecular marker of RCC by using hepatocyte nuclear factor 4A (HNF4A), a transcription factor implicated in RCC pro
OBJECTIVE: The aim of the study was to investigate the associations of total sleep time (TST) and occupational stress based on the Brief Job Stress Questionnaire (BJSQ) with cholesterol levels in an occupational cohort of Japanese office workers. METHODS: The present study is a secondary analysis of a subset of participants from a randomized controlled trial. Participants were 179 employees from 5
The Qinghai-Tibet Plateau (QTP) serves as the source of many large rivers in Asia, and also serves as a natural habitat for rare wildlife and a genetic reservoir for plateau species. The exceptional ecological environment of the QTP has fostered diverse fish species. However, due to climate change and human activities, fish species in this area are facing serious threats, while large spatial scale
BACKGROUND: Early glottic cancer can be treated with laser resection or radiotherapy. In an earlier study, we found that voice function after laser resection was inferior to that after radiotherapy.OBJECTIVES: This study was designed to determine if reduced margins at laser resection improved voice function without impairing oncologic results.METHOD: A total of 268 patients with previously untreat
Precipitation is intrinsically associated with high uncertainty, which is exacerbated exponentially over time—especially concerning climate change. However, the current design practice in urban drainage infrastructure remains firmly bound to deterministic assumptions regarding the design load. This approach is too simplified—focusing only on the return period of the design event—and ignores the co
Creep of concrete structures is in most cases regarded as a serviceability problem that may have impacts on maintenance and repair costs but cannot lead to structural collapse. However, several structural collapses during the past decades have been, at least partly, attributed to excessive creep deformations. Recent studies suggest that concrete creep may be further exacerbated by climate change.
This book challenges earlier understandings of early modern dissertations as unimaginative academic exercises. It argues for their continuous importance in scholarly and scientific discourse, and describes the richness and diversity of their subjects and themes. The book contains a complete catalogue of the almost 20,000 Swedish dissertations defended in Uppsala, Lund and Åbo, 1600 to 1820. The ca
Warmer temperatures and the combined effects of wind and water erosion leads to serious soil loss. Identifying the contribution of different drivers to wind and water compound erosion can improve soil erosion management in the watershed. Accordingly, we calculated the erosion energy based on energy theory and applied the mutation test and trend analysis to explore environmental drivers, runoff, an
Recent research has explored the potential of using the dynamic response of passing vehicles to conduct Structural Health Monitoring (SHM) efficiently. Various types of vehicles, including cars, vans, trucks, and even manually propelled carts, have been employed in this approach, with different configurations of exciters and receivers. A noteworthy development in this field involves the inclusion
At ANKA, the Karlsruhe synchrotron radiation source, the so called short bunch-length operation mode allows the reduction of the bunch length down to a few picoseconds. The micro-bunching instability resulting from the high degree of longitudinal compression leads to fluctuations in the emitted intensity in the THz regime, referred to as bursting. For extremely compressed bunches at ANKA bursting
Background: Cancer affects not only the person with the disease but those around them. Being a family member is described as strenuous and, often, associated with stress, anxiety and feelings of loneliness. There is a heightened risk of distress for family of those with fast-progressing, severe oesophageal or gastric cancer. Early palliative care involving family is vital yet often overlooked. In
