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Type 2 diabetes (T2D) is caused by insufficient insulin secretion from pancreatic β-cells. To identify candidates contributing to T2D pathophysiology, we studied human pancreatic islets from ~300 individuals. We found 395 differentially expressed genes (DEGs) in islets from individuals with T2D, including, to our knowledge, novel (OPRD1, PAX5, TET1) and previously identified (CHL1, GLRA1, IAPP) ca

This article explores the intersection between the indiscernible forces of urbanisation and the materialisation of architectural form. Taking the design of architectural concept for an Accessory Dwelling Unit (ADU) at Råå in Sweden as an applied research project, the article argues that new techniques are needed to analyse interactions between artistic intentionality and indiscernible forces, and

AIMS: Experiencing an acute myocardial infarction (AMI) is a life-threatening event and use of statins can reduce the probability of recurrence and improve long term survival. However, the effectiveness of statins in the real-world setting may be lower than the reported efficacy in randomized clinical trials. Therefore, we aimed to investigate whether low statin treatment adherence during the year

November 2011 saw the opening of the exhibition "Archeovirtual" organized by CNR ITABC - Virtual Heritage Lab - and V-MusT Network of Excellence, in Paestum, Italy, under the general direction of BMTA1. The event, that was part of a wider European project focus on virtual museums, turned to be a great opportunity to show many different projects, applications and installations about Virtual Reality

Aims: The aim is to discuss implications of consensus culture in combination with media policy in Sweden with regard to the Swedish COVID-19 strategy in the spring of 2020. Methods: Investigation of prerequisites for scrutiny by the Swedish mass media of the Swedish strategy in the spring of 2020 based on discussion regarding consensus culture, media structure and postmodernism in science, politic

The rules of conduct given to people living with HIV in Sweden in accordance with the Swedish Communicable Diseases Act stipulate disclosure obligation to sexual partners and mandatory condom use. Since 2013, treating physicians have the possibility to exempt patients from this disclosure obligation when no considerable risk of transmission is present. This study explored experiences of communicat

This article addresses the question whether maternal mortality should be excluded from the study of excess female mortality. This phenomenon points to lower survival chances for women in certain age groups as opposed to men in the same age group. The existence of excess female mortality has been established for a number of European countries, primarily for the nineteenth century period, and it has

This conclusion combines insights from the analysed of urban conflicts over peace(s) to answer the principal research question. The subsequent argument is that the postwar city reinforces rather than transcends its continuities of war into peace because urban conflicts over peace(s) attack its transcending potential and enhance its destructive potential while the city itself—untouched by postwar c

Recent scandals in Iran's province of Gilan have exposed a deep-seated hypocrisy within the Islamic regime, revealing a contradiction between public moral posturing and private conduct.High-ranking officials have been caught in explicit acts, leading to public outrage. These scandals are not isolated incidents but reflect a systemic failure to uphold Islamic laws and moral codes, calling into ques

This art short film examines clichéd images of vulnerable urban places in Sweden by juxtaposing stereotypes of marginalization, safety, commerce, and everyday life. The research aim is to use kitsch art and playful elements to intervene in the conventional thinking of these places as problems in the margins of society.The medium of the short film enables us to bring to life the empirical material

Parental dying is a life changing experience for children. This study explores children’s strategies and (inter)actions in their everyday life when facing critically ill parents and imminent death, from the children’s and parents’ perspectives. A qualitative systematic review was carried out, registered in PROSPERO (CRD42022306862). A literature search and screening in six databases resulted in ei

Clinical pain is often linked to poor body mechanics, with individuals sometimes presenting multiple painful disorders. Such disorders may be influenced by behaviors that affect the general resiliency and health of the musculoskeletal system. We aimed to develop a self-reported scale using the Malmö Diet and Cancer Study questions on work-related body mechanical exposures. An expert panel identifi

This contribution focuses on narratives and experiences of belonging and exclusion among convert members of Three Wheels, a Japanese Shin Buddhist temple in London, to investigate how difference is incorporated into transnational Buddhism. Three Wheels, whose members include both diasporic Japanese and convert Buddhist Europeans, occupies a marginal position within both transnational Shin Buddhism

This article focuses on expressions of bereavement and religious coping in medieval miracle stories from Sweden. The stories come from the collections of St. Birgitta (Bridget) of Sweden, the Blessed Bishop Nicolaus Hermanni (Sw. Nils Hermansson) of Linköping and the Blessed Katarina of Vadstena, and were recorded in the fourteenth and fifteenth centuries. Catherine M. Sanders’s modern five stages

This paper investigates how compassion with and understanding for the suffering of the other is constructed by the media and why certain choices are made with respect to coverage and framing. Articles published in the Swedish newspaper Dagens Nyheter in relation to three different cases that all take place in Haiti have been surveyed by using quantitative content analysis and qualitative textual a

Across different domains, justice is considered either from a perspective concerning mind-independent features of a situation or from a perspective related to mind-dependent motives, traits or emotions. Although these approaches have generated valuable insights, they remain largely disconnected from each other. What is missing is an integrative framework that can explain how the objective features

Loneliness in advanced age has become one of the societal concerns considering its detrimental effects on physical and mental health of older people. Information and communication technologies show the potential to prevent or tackle loneliness and social isolation among older people. Given a percentage of the older population feeling lonely, loneliness in older age has been increasingly recognized