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OBJECTIVES: To assess the extent to which knee extensor strength and weight in adolescence are associated with knee osteoarthritis (OA) by middle age.METHODS: We studied a cohort of 40 121 men who at age 18 years in 1969/1970 underwent mandatory conscription in Sweden. We retrieved data on isometric knee extensor strength, weight, height, smoking, alcohol consumption, parental education and adult

Important factors behind high levels of vulnerability and low adaptive capacity to climate variability and change in the developing world are direct reliance on natural resources, poverty and limited abilities to adapt financially and institutionally. In this study, focusing on the Lake Victoria Basin, a multitude of stressors on livelihoods, including climate related factors, are faced by the rur

An almost k-wise independent sample space is a small subset of m bit sequences in which any k bits are “almost independent”. We show that this idea has close relationships with useful cryptologic notions such as multiple authentication codes (multiple A-codes), almost strongly universal hash families and almost k-resilient functions. We use almost k-wise independent sample spaces to construct new

Background: The Bruton's Tyrosine Kinase (BTK)-inhibitor ibrutinib is highly active in mantle cell lymphoma (MCL) but may inhibit response to anti-CD20 antibody as previously shown in CLL models. We investigated how antibody-dependent cellular cytotoxicity (ADCC) induced by type I/II anti-CD20 antibodies was affected by treatment with ibrutinib in MCL. Furthermore, we investigated if lenalidomide,

Stars formed in clusters can encounter other stars at close distances. In typical open clusters in the Solar neighbourhood containing hundreds or thousands of member stars, 10-20 per cent of Solar-mass member stars are expected to encounter another star at distances closer than 100 au. These close encounters strongly perturb the planetary systems, directly causing ejection of planets or their capt

The main objective was to compare short wave radiation from Thorn lamp to solar radiation. In sun all manikin front zones get more or less evenly radiated but in the lab the radiated power reaches some zones more than others. Tests were carried out on the thermal manikin Tore under clear sky in a building corner facing the sun. The manikin was turned so that in the end of each trial the sun faced

Computer-based design analysis is nowadays a common activity in most development projects. Used for design evaluation, verification, validation, or as a support for design exploration, it fulfils an important support function for the engineering designer, thus making it essential to have an operationally efficient and effective integration between both the engineering design and design analysis ac

It is well-known that the morphology of urban areas modifies the variations of climate variables at microscale; known as microclimate conditions. The complexity of urban morphology can lead to undesired wind conditions or excessive air temperature; particularly in extreme weather conditions. This study attempts to quantify the impacts of urban morphology on the evolution of wind speed and air temp

Type 1 diabetes (T1D) is an autoimmune disease caused by the T cell-mediated destruction of the pancreatic insulin-producing beta cells. Currently there are no widely accepted and standardized assays available to analyse the function of autoreactive T cells involved in T1D. The development of such an assay would greatly aid efforts to understand the pathogenesis of T1D and is also urgently require

In this paper, the freeze-thaw stability of mayonnaise type oil-in-water emulsions is studied. The emphasis of the experiments have been on the properties of the dispersed oil phase as only small, or no effects, were observed from initial experiments on changing the properties of the aqueous phase within the investigated ranges. Different vegetable oils are investigated in order to relate the comp

Context:A common genetic variant (rs10423928, A-allele) in the glucose-dependent insulinotropic polypeptide receptor gene (GIPR) is associated with decreased insulin secretion. Glucose-dependent insulinotropic polypeptide is secreted after food consumption and gipr knockout mice fed a high-fat diet are protected against obesity and disturbances in glucose homeostasis. Objective:Our objective was

The increasing use of wireless technology utilizing unlicensed frequency bands calls for more in-depth analysis of interference and coexistence between systems. In this paper a framework is presented for detailed analysis of the performance of coexisting networks in shared frequency bands. The framework allows for multiple packet lengths to be used by the communicating devices and the analysis is

The management of construction tolerances is a necessary and routine part of the construction activity and is normally brought to our attention only when failures are reported. In a study of tolerance management, the authors found widespread evidence of the same failures and the reasons for them. There seems to be no shortage of experience of the effects of failures in tolerances or of knowledge a

Nature provides us with a vast source of inspiration. However, given industrial designers' open-mindedness and inquisitiveness, a surprisingly limited set of nature-derived symbols continues to be popular in this creative discipline. Rather than designing products mimicking nature, it is probably more rewarding designing them based on the natural principles leading to its growth and form. However,

Context: Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are cleaved by dipeptidyl peptidase-4 (DPP-4); plasma activity of DPP-4 may be increased in obesity. The impact of this increase on incretin hormone secretion and metabolism is not known. Objective: The aim of the study was to assess incretin hormone secretion and degradation in lean and obese nondiabet

This paper aims to support the decision-making tasks regarding the integration of packaging development into product development. Based on the study of the interactions of the product and packaging during the whole product life cycle, a set of packaging-related factors was extracted and mapped to a general product development model, which at a strategic level can be used to define an integrated pr

Popular Abstract in Swedish Avhandlingen är en historisk-komparativ analys av en konflikt som har uppstått i Miskito's ekonomiska system under 1900-talet avseende exploateringen av kommunalt ägda resurser. Studien är baserad på empiriskt material insamlat i en Miskito/Creole by på Atlantkusten i Nicaragua på 1990-talet. Under den s k enklavperioden (1860-1960) tjänade Miskito män pengar som lönearThis dissertation is a historical-comparative analysis of a conflict that has developed in the economic system of the Miskito in the 20th century, concerning the use of common property resources. The study is based on empirical material collected in a Miskito/Creole village on the Atlantic Coast of Nicaragua in the 1990s. During the enclave period (1860-1960) Miskito men earned money as wage labou

How much is "anti" in the "anti-globalization" movement? And how much is "pro", and for what? In this paper I will analyze some common features, and divisions between organizations in the so called anti-globalization movement, with focus on the political articulations and different ways of political struggle. How is a common identity and a common adversary of the disparate movements constructed wi