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Cancer is one of the leading causes of death globally. Novel therapeutics is urgently needed to advance treatment, especially for generalized disease where current treatment options have a poor prognosis. In particular, targeted therapy that can address genetic changes would be of great value. RNA interference is an evolutionary conserved gene regulatory mechanism that can be used by introducing e
Affinity two-phase partitioning based on an immunoaffinity sandwich approach for the rapid and selective purification of membranes is presented in this thesis. The method was developed by studying different parameters governing the affinity partitioning of model membranes. To this end, biotinylated liposomes were used. They specifically distributed to the bottom phase of a poly (ethylene glycol)/d
Monitoring in the biomedical field is rapidly emerging as the most important application area of miniaturized analytical devices. Diagnostics, disease monitoring, drug development, and medical research are important areas taking full advantage of the short response time, reduced sample consumption, low costs, and reduced power requirements of miniaturized analytical tools. Such tools can either in
The paravermal cerebellar cortex contains three spatially separate zones (the C1, C3 and Y zones) which form a functionally coupled system involved in the control of voluntary limb movements. A series of 'modules' has been postulated, each defined by a set of olivary neurons with similar receptive fields, the cortical microzones innervated by these neurons and the group of deep cerebellar nuclear
Popular Abstract in Swedish Parkinsons sjukdom är den näst mest vanliga neurodegenerativa sjukdomen och den drabbar 2% av befolkningen över 65 år. Sjukdomen kännetecknas av en gradvis ökad förlust av dopaminproducerande nervceller. Symtomen tilltar successivt och leder framförallt till allvarliga fördröjningar i rörelsemönstret. Dessvärre, när de första symptomen väl upptäcks, så har redan 50% av Parkinson's disease (PD) is the second most common neurodegenerative disease and affects 2% of the population over 65 years of age. The disease is characterized by the progressive loss of dopaminergic neurons. Over time, symptoms increase and, in particular, lead to a dramatic slowness of movements. Unfortunately, when the fi rst symptoms are discovered, more than 50% of the dopaminergic neurons a
All hematopoietic cells originate from hematopoietic stem cells (HSC) residing in the BM. The process of differentiation, through which HSCs generate progenitors and subsequently mature blood cells has been extensively studied but many of the regulatory mechanisms involved remains elusive. The classical model for hematopoiesis has been established based on the identification of common myeloid prec
Can you grow a brain in a dish? How do blood stem cells look in the microscope? Can you decipher the code of life? These and many more questions will be answered by motivated PhD students, postdoctoral fellows, and senior scientists during UniStem Day on March 15th, 2019. Below you find a list of workshops and hands-on sessions that we will offer during UniStem Day at Lund Stem Cell Center. The wo
https://www.stemcellcenter.lu.se/research-school/program-overview/public-engagement/unistem2019/workshops - 2026-07-17
Annual Report 2025 LUND SOCIAL SCIENCES METHODS CENTRE Page 1 of 13 Lund Social Sciences Methods Centre Reg. No. SAMV 2026/26 Table of contents Introduction ..................................................................................................................................... 3 Lund Social Science Methods Centre 2025 ...................................................................
https://www.sam.lu.se/en/sites/sam.lu.se.en/files/2026-06/Methods-Centre-Annual-Report-2025-webb.pdf - 2026-07-18
Delegated decisions, enclosure 2 Travel Grants Applicant SEK Activity Approved by Group affiliation Date of approval 1 Zeinab Rafiee 18 000 AD/PD 2025, Vienna, Austria, 1-5 April 2025 Maria H Nilsson Malin Wennström 2025-02-18 2 Xiaoni Zhan 17 855 Synuclein Meeting 2025, Cambridge, UK, 8-11 April 2025 Maria H Nilsson Jia-Yi Li 2025-02-18 3 Andreas Carlsson 8 125 Amyloid Diseases and Amyloid Mechan
https://www.multipark.lu.se/sites/multipark.lu.se/files/2025-06/2025-05-23%20MultiPark%20board%20minutes.pdf - 2026-07-18
This paper describes new sample cells and techniques for in situ powder X-ray diffraction specifically designed for gas absorption studies up to ca 300 bar (1 bar = 100 000 Pa) gas pressure. The cells are for multipurpose use, in particular the study of solid-gas reactions in dosing or flow mode, but can also handle samples involved in solid-liquid-gas studies. The sample can be loaded into a sing
Hematopoietic stem cells (HSCs) are defined by their unique properties to self-renew and differentiate into all hematopoietic cell lineages. Residing in the bone marrow (BM), adult HSCs are organized in a hierarchy of cells that differ in their self-renewal and proliferative capacity. Exact relationships of the various cells in the hematopoietic hierarchy, their potential to commit to certain line
Semiconductor nanowires are a promising candidate for next-generation solar cells. However, the optical response of nanowires is, due to diffraction effects, complicated to optimize. Here, we optimize through optical modeling the absorption in a dual-junction nanowire-array solar cell in terms of the Shockley-Quessier detailed balance efficiency limit. We identify efficiency maxima that originate
1 1 Application CARES school Invitation to all PhD students in cancer research at Lund University and University of Gothenburg to apply to become a research fellow in the new CARES program 2026-2027 The Cancer Research South (CARES) school was initiated in 2014 with support from the Swedish Cancer Society. The research school was relaunched in a new format, starting in January 2022. The new CARES
https://www.lucc.lu.se/internal/sites/lucc.lu.se.internal/files/2026-01/Application%20CARES%202026_1.docx - 2026-07-18
