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Despite an advanced understanding of disease mechanisms, the current therapeutic regimen fails to cure most patients with acute myeloid leukemia (AML). In the present study, we address the role of ribosome assembly in leukemia cell function. We apply patient datasets and murine models to demonstrate that immature leukemia cells in mixed-lineage leukemia-rearranged AML are characterized by relative
Conference venue Address: Inspira, Medicon Village, Scheelevägen 4, 223 63 Lund Abstracts Devres 2024 The complete list of abstracts presented at Devres 2024 (Pdf, 779 kb, opens i new window) Print friendly version of the programme Print friendly version of the programme (Pdf, 1,7 MB, opens in new window) Conference Day 1 – 21 October Conference venue: Inspira, Medicon Village, Scheelevägen 4 13.
https://www.lucsus.lu.se/devres2024/programme-devres-2024 - 2026-07-15
Electrophysiology Core Facility The F09 setup is centered around a Molecular Devices Axopatch 700B amplifier with a Digidata 1440 digitizer. It is designed for use with both cells grown on coverslips and brain slice preparations, allowing for up to 2-channel recordings. These recordings can be paired with electrical stimulation via an isolated current stimulator or local pharmacological stimulatio
https://www.stemcellcenter.lu.se/core-facilities/electrophysiology-core-facility/f09-platform - 2026-07-15
Cancer cells in solid tumors experience hypoxia, a condition of low O2 concentration, since their O2 demand exceeds the supply from the surrounding vasculature. However, how these cells adapt to hypoxia requires further elucidation. Here, we use a transparent phosphorescent thin film to visualize the self-generated hypoxia field of prostate cancer cells and quantify local O2 consumption rates, mea
Hematopoietic stem cells (HSCs) are rare cells on top of the differentiation hierarchy of hematopoiesis. HSCs are unique in their combined capacity to differentiate into all mature blood lineages and self-renew to maintain the HSC pool. Based on classical models of hematopoiesis in mouse, the self-renewal potential of HSCs is gradually and step-wise lost during the transition from long term (LT)-H
Induced pluripotent stem cells (iPSCs) can in principle differentiate into any cell of the body, and have revolutionized biomedical research and regenerative medicine. Unlike their human counterparts, mouse iPSCs (miPSCs) are reported to silence transposable elements and prevent transposable element-mediated mutagenesis. Here we apply short-read or Oxford Nanopore Technologies long-read genome seq
Wideband code division multiple access (WCDMA) systems are interference-limited. When a WCDMA system operates at nearly full capacity, admitting a new user may affect the stability of the system. Therefore, the proper call admission control (CAC) is crucial and should balance between quality of service (QoS) requirements for the new user as well as for the existing users and the required high capa
Earlier detailed studies of cnidarian planula larvae have revealed a simple nervous system but no eyes or identifiable light sensing structures. Here, we describe the planula of a box jellyfish, Tripedalia cystophora, and report that these larvae have an extremely simple organization with no nervous system at all. Their only advanced feature is the presence of 10-15 pigment-cup ocelli, evenly spac
Brevmall Facul ty o f Medic ine Department o f Labora tory Medic ine, Lund Announcement: Post doc scholarship in Spatial Chemical Mapping of Normal and Transformed Tissue Scholarship The aim of the scholarship is to offer an opportunity for a postdoc candidate with any background within the medical sciences or natural sciences to learn from a uniquely transdisciplinary research team. The team work
Doctoral student Contact details Email: alexander [dot] degener [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Room number: 456 Service point: 16 WebpageAlexander Degeners profile in Lund University research portalAbout me:Before starting my PhD, I did a master’s in physics at Lund University, focusing on machine learning and computational models appl
https://www.cec.lu.se/alexander-degener - 2026-07-15
Suggesting colloquium speakers | Centre for Mathematical Sciences Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not sto
https://www.maths.lu.se/english/research/seminars/colloquium/suggesting-colloquium-speakers/ - 2026-07-11
Agenda 2030 Graduate School monthly newsletter #9 2024-10-04 Ylva van Meeningen Hi! Thank you all who were part of the PhD conference on Sustainable Development 24th of September, both you who organized activities and those who participated. The conference was something special this time, not only due to the diverse topics that were presented but there was also an open and caring atmosphere which
The diphtheria toxin A chain (DTA) was gene targeted into the Joining chain (J chain) locus to create a mouse strain selecting against J chain-expressing cells, JDTA mice. Serum immunoglobulin (Ig)M and serum IgG were reduced six to eightfold, while serum IgA was elevated 14-fold in these mice. JDTA mice were immune competent although the serum Ig response compared with wild-type mice was reduced
Molecular analysis of circulating and disseminated tumor cells (CTCs/DTCs) has great potential as a means for continuous evaluation of prognosis and treatment efficacy in near-real time through minimally invasive liquid biopsies. To realize this potential, however, methods for molecular analysis of these rare cells must be developed and validated. Here, we describe the integration of imaging mass
