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This article is part of the Dendritic Cell Guidelines article series, which provides a collection of state-of-the-art protocols for the preparation, phenotype analysis by flow cytometry, generation, fluorescence microscopy, and functional characterization of mouse and human dendritic cells (DC) from lymphoid organs, and various nonlymphoid tissues. Within this article, detailed protocols are prese
Tissue patterning during development is thought to be driven largely by gene regulatory responses to spatial gradients of molecular signals, known as morphogens. In this thesis, early patterning of the human neural tube is studied using two different gene regulatory network models. The models portray patterning in the rostral-caudal direction as a response to gradients of WNT and FGF signalling. T
The role of long non-coding RNAs (lncRNAs) in early mammalian embryogenesis remains unclear due to the complexity of the regulatory mechanisms involving lncRNAs and the limited availability of embryo samples. Stem cell-based models, such as mouse gastruloids, provide new ways to address these challenges. Here, we investigate the function of ultra-conserved lncRNA T-UCstem1 in mammalian body plan f
Postdoc Contact details Email: christian [dot] lehmann [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageChristian Lehmanns profile in Lund University research portal Publications Displaying of publications. Sorted by year, then title. Filter by type AllArticle Filter First large-scale spatial and velocity patterns of local metal
https://www.geology.lu.se/christian-lehmann - 2026-07-10
To capture highly dynamic biological processes at cellular resolution is a recurring challenge in biology. Here we show that combining selective-volume illumination with simultaneous acquisition of orthogonal light fields yields three-dimensional images with high, isotropic spatial resolution and a significant reduction of reconstruction artefacts, thereby overcoming current limitations of light-f
Chain-elongated analogues of (Z)-dec-5-enyl acetate, a pheromone component of the turnip moth, Agrotis segetum, have been studied. The conformational energies required for the analogues to mimic spatial relationships in the parent molecule, assumed to be crucial for the receptor interaction, were calculated by molecular mechanics (MM2). The calculated energies show a striking correlation with meas
4 June 2026 11:00 to 11:30 | Master Thesis presentation by Vilhelm Conradi & Hugo Nelsson Title: Multistage Optimal Transport evaluated on scRNA-seq Human Bone Marrow dataAuthor: Vilhelm Conradi & Hugo NelssonDate & Time: June 4th, 11:00–11:30Location: Seminar Room M 3170-73 in the M-building, LTHSupervisor: Anders Rantzer and Karl RydénExaminer: Magnus FontesAbstract:With novel techniques like
https://www.control.lth.se/calendar/multistage-optimal-transport-evaluated-scrna-seq-human-bone-marrow-data - 2026-07-11
Homeostasis of short-lived blood cells is dependent on rapid proliferation of immature precursors. Using a conditional histone 2B-mCherry-labeling mouse model, we characterize hematopoietic stem cell (HSC) and progenitor proliferation dynamics in steady state and following several types of induced stress. HSC proliferation following HSC transplantation into lethally irradiated mice is fundamentall
In the adult murine brain, neural stem cells (NSCs) can be found in two main niches: the dentate gyrus (DG) and the subventricular zone (SVZ). In the DG, NSCs produce intermediate progenitors (IPs) that differentiate into excitatory neurons, while progenitors in the SVZ migrate to the olfactory bulb (OB), where they mainly differentiate into inhibitory interneurons. Neurogenesis, the process of ge
Welcome to NOSA 2026 3-5 March in Lund.Since its beginning in 1978, the Nordic Society for Aerosol Research (NOSA) has organised annual symposia, bringing together members from various institutes and research groups worldwide. NOSA provides a platform for experienced and early-career scientists to meet and exchange ideas.The theme for NOSA 2026 is Impacts of Aerosol Science & Technology. Symposium
https://www.eat.lth.se/en/nosa-2026 - 2026-07-11
