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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193006 hits
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The problem: wearable eye trackers deliver eye-tracking data on a scene video that is acquired by a camera affixed to the participant’s head. Analyzing and interpreting such head-centered data is difficult and laborious manual work. Automated methods to map eye-tracking data to a world-centered reference frame (e.g., screens and tabletops) are available. These methods usually make use of fiducial
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Ammonia (NH3) emerges as a promising carbon-free fuel, necessitating an understanding of its fundamental combustion properties, particularly the laminar burning velocity (SL), at very high unburnt temperatures (Tu). Despite this need, a consensus on the relationship between SL and Tu across a broad temperature range has not yet been established. This study investigated the SL vs. Tu relationship f
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Alterations in mitochondrial metabolism in obesity may indicate disrupted communication between mitochondria and nucleus, and DNA methylation may influence this interplay. Here, we leverage data from the Finnish Twin Cohort study subcohort (n = 173; 86 full twin pairs, 1 singleton), including comprehensive measurements of obesity-related outcomes, mitochondrial DNA quantity and nuclear DNA methyla
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Currently used methodologies for quality control of residual leukocytes and erythrocytes in leukocyte-depleted plasma are either expensive or time-consuming. It has been proposed that urine dipsticks could be used as a screening method for residual erythrocytes. The aim was, therefore, to evaluate if urine dipsticks could be used to detect residual erythrocytes and also residual leukocytes in leuk
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Extreme environmental events such as Heat Waves (HWs), cold waves, and droughts intensified by climate change are increasingly associated with adverse health outcomes. In this study, investigation of the extreme temperature across Uttar Pradesh (U. P.), one of India’s largest and densely populate states has been done. Using high-resolution climate data from the Providing REgional Climates for Impa
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Objective: Worse women's outcomes after elective standard endovascular aneurysm repair have been widely reported. Similar data have surfaced from cohorts undergoing fenestrated and branched repair; however, studies reporting from a sex perspective are rare and mostly limited to single centre designs. This study aimed to examine survival following nationwide complex endovascular repair according to
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Biotechnologically produced (R)-3-hydroxybutyrate is an interesting pre-cursor for antibiotics, vitamins, and other molecules benefitting from enantioselective production. An often-employed pathway for (R)-3-hydroxybutyrate production in recombinant E. coli consists of three-steps: (1) condensation of two acetyl-CoA molecules to acetoacetyl-CoA, (2) reduction of acetoa
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Coronary artery disease is one of the leading causes of mortality worldwide. While early identification and treatment of major cardiovascular risk factors are crucial, recent data suggest the possibility of non-invasively detecting early stages of coronary atherosclerosis and potentially stabilizing or even reversing the burden of atherosclerosis with innovative and existing treatments. Moreover,
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I have been studying public squares in Lund and Malmö over the past twenty years often focusing on how their uses have changed over the decades. Looking back at these studies, I have seen how the squares of these two cities increasingly have turned into crowded pedestrianized areas for extraordinary events and weekend or evening entertainment, rather than catering for more mundane needs.
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Cardiovascular-kidney-metabolic (CKM) syndrome affects approximately 90% of US adults, arising from the convergence of metabolic dysfunction, chronic kidney disease (CKD), and cardiovascular disease (CVD). These conditions create self-reinforcing cycles of multiorgan damage, substantially increasing mortality risk. The American Heart Association’s 2023 staging framework stratifies CKM from stage 0
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CONTEXT: Uptake of organic farming falls short of stated sustainability targets, particularly in highly productive regions where adoption could mitigate environmental impacts of intensive farming. Several hypotheses have been advanced to explain the constraints on adoption, but these have not been assessed within an integrative, interdisciplinary framework.OBJECTIVE: The objective was to develop a
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Correlations between event-by-event fluctuations of anisotropic flow harmonics are measured in Pb-Pb collisions at a center-of-mass energy per nucleon pair of 5.02 TeV, as recorded by the ALICE detector at the LHC. This study presents correlations up to the hexagonal flow harmonic v6, which was measured for the first time. The magnitudes of these higher-order correlations are found to vary as a fu
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Taurine, an amino sulfonic acid abundant in seafood and meat, has been proposed to have a potential role in the prevention of metabolic dysfunction-associated steatotic liver disease (MASLD) due to its antioxidant and anti-inflammatory properties. However, the association between dietary taurine intake and MASLD remains unclear in human populations. Also, data on dietary taurine intake among adult
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This article examines the emerging migration corridor between Uzbekistan and Sweden based on interviews, focus groups, and data from a survey conducted in both countries in 2024. Although small in scale, this corridor is analytically significant for understanding the diversification of Uzbek migration beyond Russia and Turkey. Findings show that demographic pressures, limited employment, and envir
