Filetype
The ability to control the morphology of organic semiconductor nanoparticles is of paramount importance for applications in organic photovoltaics, photocatalysis, and photo-triggered biological applications. In this paper, we demonstrate that nanoprecipitation is a powerful technique to provide a variety of morphologies in binary blends of organic semiconductors. By investigating seven different d
Historical archaeology in Scandinavia is an expand- ing field, but despite its global nature, the discipline is trapped in methodological nationalism. The early modern and modern societies are generally studied us- ing the current national borders even though the ma- terial culture should not be constrained in this way. By illustrating with both theoretical and empirical ex- amples, the objective
Introduction: Cell-free DNA is an emerging marker of allograft injury, yet its role in the immediate phase of ischemia–reperfusion injury remains incompletely understood.Methods: In this prospective cohort of 127 kidney transplant recipients (86 deceased donors, 41 living donors), intraoperative plasma samples were collected systemically pre-implantation and from the allograft vein postreperfusion
Pancreatic cancer remains one of the deadliest cancers due to its resistance to conventional therapies, necessitating the development of novel treatment strategies. This study investigates the anticancer potential of caulerpin, a bisindole alkaloid derived from the invasive marine alga Caulerpa cylindracea, encapsulated in biocompatible cubosomes. Caulerpin was sustainably extracted via microwave-
The building permit is usually the final decision of urban governance for public authorities, whereby the private actor is given the right to construct at the urban plot. But in urban areas there is an urban context, which calls the attention to the need of a planning perspective of the assembled built environment. Detailed plans are required, and they ought to be considered in a total urban or mu
Background: White adipose tissue (WAT) dysfunction including an aberrant expression of miRNAs is strongly associated with the risk of developing type 2 diabetes (T2D), with limited evidence linking early changes in the WAT-derived miRNAs and T2D. The present study aims to identify early miRNome changes prognostic for T2D in mice and humans. Methods: Gonadal (g) WAT of diabetes-resistant and diabet
Extreme environmental events such as Heat Waves (HWs), cold waves, and droughts intensified by climate change are increasingly associated with adverse health outcomes. In this study, investigation of the extreme temperature across Uttar Pradesh (U. P.), one of India’s largest and densely populate states has been done. Using high-resolution climate data from the Providing REgional Climates for Impa
Objective: Worse women's outcomes after elective standard endovascular aneurysm repair have been widely reported. Similar data have surfaced from cohorts undergoing fenestrated and branched repair; however, studies reporting from a sex perspective are rare and mostly limited to single centre designs. This study aimed to examine survival following nationwide complex endovascular repair according to
The gut microbiota is associated with human health and disease. Here we conducted a genome-wide association study of host genetic factors influencing gut microbiota composition in 12,652 individuals from the Trøndelag Health Study (HUNT), with replication in Nordic cohorts (n = 16,017–21,976). We identified 12 reproducible SNP–species associations across six genomic loci, including known (LCT, ABO
Disruptions in gut microbiome are implicated in cardiometabolic disorders and other health outcomes. Antibiotics are known gut microbiome disruptors, but their long-term consequences remain underexplored. Here we combined individual-level data from the Swedish Prescribed Drug Register with fecal metagenomes of 14,979 adults to examine the association between oral antibiotic use over 8 years and gu
Background: C3 is highly expressed in human and rodent pancreatic islets, which secrete insulin to regulate blood glucose homeostasis. We have previously shown that cytosolic C3 protects pancreatic beta-cells from stress, by allowing cytoprotective autophagy, and that the same intracellular pool of C3 also protects beta-cells from cytokine-induced apoptosis. Methods: We now generated a beta-cell s
Determining the drivers of intraspecific variation in cognitive performance is crucial for understanding how cognition evolves, but experimental studies are scarce. Several correlational studies have supported the hypothesis that living in larger groups enhances cognitive performance. However, empirical explanations of whether and how living in large groups causally affects individual cognitive pe
The mast cell granule metalloprotease CPA3 is proposed to have important tissue homeostatic functions. However, the basal CPA3 mRNA and protein expression among mast cell populations has remained poorly investigated. Using a novel histology-based methodology that yields quantitative data on mRNA and protein expression at a single-cell level, the present study maps CPA3 mRNA and protein throughout
The gut microbiota has been associated with many diseases, including endometriosis. However, very few studies have been conducted on this topic in human. This study aimed to investigate the association between endometriosis and gut microbiota. Women with endometriosis (N=66) were identified at the Department of Gynaecology and each patient was matched with three controls (N=198) from the general p
When you think of fungi, you’ll probably picture a huddle of chubby brown mushrooms, or the large, red-capped toadstools you stumble across in the woods. In doing so, you’re reducing fungi to their reproductive organs – tasty or striking as they may often be.
