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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193123 hits

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Interspecific hybridization is the process where closely related species mate and produce offspring with admixed genomes. The genomic revolution has shown that hybridization is common, and that it may represent an important source of novel variation. Although most interspecific hybrids are sterile or less fit than their parents, some may survive and reproduce, enabling the transfer of adaptive var

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Soil carbon (C) reservoirs held in forests play a significant role in the global C cycle. However, harvesting natural forests tend to lead to soil C loss, which can be countered by the establishment of plantations after clear cutting. Therefore, there is a need to determine how forest management can affect soil C sequestration. The management of stand density could provide an effective tool to con

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1. Nature conservation often depends on the behaviour of individuals, which can bedriven by socio-psychological factors such as a person's attitude, knowledge andidentity. Despite extensive ecological research about pollinator declines, there hasbeen almost no social research assessing the drivers of people's engagement inpollinator conservation.2. To address this gap, we used a large-scale, onlin

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Aim: We aimed to study the feasibility and tolerability of a combination therapy consisting of glutamic acid decarboxylase (GAD-alum), Etanercept and vitamin D in children and adolescents with newly diagnosed with type 1 diabetes (T1D), and evaluate preservation of beta cell function. Material and Methods: Etanercept Diamyd Combination Regimen is an open-labelled multi-centre study pilot trial whi

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Through changes in climate and other environmental factors, alpine tundra ecosystems are subject to increased cover of erect shrubs, reduced predictability of rodent dynamics and changes in wild and domesticated herbivore densities. To predict the dynamics of these ecosystems, we need to understand how these simultaneous changes affect alpine vegetation. In the long term, vegetation dynamics may d

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For many years, questions about the future have been marginalised within the social sciences: asking how we might live in a post-fossil society, or what are the key decisions and events that could take us there, has been seen as outside of the disciplinary scope. In this paper – which takes as its point of departure the ‘speculative turn’ that is increasingly inspiring a range of works, from fores

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While traditional forms of urban planning are oriented towards the future, the recent turn towards experimental and challenge-led urban developments is characterized by an overarching presentism. We explore in this article how an experimental approach to urban planning can consider the long-term through setting-up ‘conversations with a future situation.’ In doing so, we draw on a unique experiment

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The objective of integrated pest and pollinator management (IPPM) is to co-manage for pest control and pollination goals. Departing from the well-established concept of integrated pest management, we include pollinator management in a hierarchical decision support system of management actions. We depict this support system as an IPPM pyramid. Priority is given to proactive measures at the base of

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It is of great importance to understand how terrestrial ecosystems will respond to global changes. However, most experimental approaches have focused on single factors. In natural systems, moisture and temperature often change simultaneously, and they can interact and shape microbial responses. Even though soil moisture and temperature are very important factors controlling microbial activity, the

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Breast cancer is the most commonly diagnosed cancer among women in Sweden, as well as worldwide. In Sweden, 8,288 women were diagnosed with invasive breast cancer in 2019, out of whom approximately 1.5% were younger than 35 years of age. Although breast cancer is relatively uncommon in young women, they tend to be diagnosed with more aggressive tumors at a more advanced stage, and have a poorer pr

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The AMP-activated protein kinase (AMPK) is a ubiquitously expressed kinase, which is activated in response to depletion of cellularenergy levels. Once active, it functions to alter cellular metabolism in a way that leads to restoration of energy levels. Therefore,AMPK is described as the key regulator of cellular energy homeostasis. Over the past years, AMPK activation has gained increasingattenti