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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192207 hits

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Crop diversification and maintenance of semi-natural habitats (grasslands and field boundaries) are suggested to enhance farmland biodiversity, but the relative importance of these factors remains poorly known. We evaluated how crop diversity and availability of semi-natural grasslands at a landscape-scale interacted with local farming management (three management types from low to high intensity:

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The direct effects of CO2 level changes on plant water availability are usually ignored in plant habitat models. We compare traditional proxies for water availability with changes in soil water (fAWC) predicted by a process-based ecosystem model, which simulates changes in vegetation structure and functioning, including CO2 physiological effects. We modelled current and future habitats of 108 Euro

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Symptoms of infection and tissue pathology are caused by the host response; not by the microbe per se. The same response is also critical for the defence and is needed to clear infection. It is therefore essential to understand how the host response is activated and to identify the critical effector mechanisms of the defence. We have studied these issues in the urinary tract infection (UTI) model.

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Background: Observational studies implicate higher dietary energy density (DED) as a potential risk factor for weight gain and obesity. It has been hypothesized that DED may also be associated with risk of type 2 diabetes (T2D), but limited evidence exists. Therefore, we investigated the association between DED and risk of T2D in a large prospective study with heterogeneity of dietary intake. Meth

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We aim to provide a long-term ecological analysis of land-use and floristic diversity in the transition from traditional to modern land-use management in the time a.d. 1800-2008 in southern Sweden. We use the Regional Estimates of Vegetation Abundance from Large Sites (REVEALS) model to quantify land-cover changes on a regional scale at 20-year intervals, based on the fossil pollen record. Florist

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Context: The dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits glucagon secretion at hyperglycemia but appears to enhance glucagon counterregulation during hypoglycemia in type 2 diabetes.Objective:The objective of the investigation was to study whether vildagliptin also improves α-cell function in type 1 diabetes (T1D). Patients and Methods: The study was a single-center, double-blind, ra

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Aims: To assess, by systematic review of the literature, (1) the prevalence and incidence of temporomandibular disorder (TMD) pain after whiplash trauma, and (2) whether treatment modalities commonly used for TMD are equally effective in patients with solely TMD pain and those with TMD/whiplash-associated disorders (WAD) pain. Methods: A systematic literature search of the PubMed, Cochrane Library

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BACKGROUND: The two-gene expression ratio HOXB13:IL17BR has been proposed to predict the outcome of tamoxifen-treated breast cancer patients. We intended to examine whether this ratio can predict the benefit of 5 years vs. 2 years of tamoxifen treatment of postmenopausal patients. A further objective was to investigate any prognostic effects of the ratio in systematically untreated premenopausal p

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Sedimentary records of invertebrate assemblages were obtained from a small lake in the Khibiny Mountains, Kola Peninsula. Together with a quantitative chironomid-based reconstruction of mean July air temperature, these data provide evidence of Holocene climate variability in the western sector of the Russian Subarctic. The results suggest that the amplitude of climate change was more pronounced in

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Agriculture's reliance on ecosystem services creates economic and ecological interdependencies between crop production and biodiversity. Interactions with mobile organisms are particularly complex because they depend on the spatial configuration of habitat at large scales. As such conserving habitat is likely to benefit multiple farmers whereas conservation costs are born individually, creating po

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Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world. It is an Epstein-Barr virus-associated malignancy with an unusual racial and geographical distribution. The host innate immune sensor genes play an important role in infection recognition and immune response against viruses. Therefore, we examined the association between polymorphisms in genes within a group of pattern

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Postmenopausal women consistently have higher phosphorus levels than similarly aged men. As it is known that estradiol induces phosphaturia in rodents, we evaluated the cross-sectional association of sex hormones with serum phosphorus in 1346 community-living older men (mean age 76) of which 18% had moderate (stage 3) kidney disease. Using linear regression with serum phosphorus levels as the depe

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This article explores the “question of the animal” in Swedish artist Ann-Sofi Sidén’s project Queen of Mud, executed between 1988 and 2004. Queen of Mud revolves around a naked female creature, smeared from top to toe in wet mud, which interferes in human affairs and challenges thereby common assumptions about the human/animal divide and the human-animal continuum. By reading Queen of Mud over aga

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Dendroclimatic investigations of subfossil Scots pine (Pinus sylvestris) from two raised bogs in southern Sweden yielded a continuous floating 1492-year long tree-ring record. By cross-dating with bog-pine chronologies from Lower Saxony, Germany, the South Swedish record was assigned an absolute age of 5219-3728 BC. The cross-match between ring-width chronologies from these two regions, separated

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Hermit beetles of the genus Osmoderma (Coleoptera: Scarabaeidae: Cetoniinae) are known for their fruity odour, which is released in large amounts by males. Two species of the genus occur in Europe, the eastern Osmoderma barnabita (Motschulsky) and the western Osmoderma eremita (Scopoli). Previous studies on Swedish populations of O. eremita showed that the compound responsible for the characterist

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A Holocene sediment sequence from Lake Seukokjaure, a subarctic lake at tree-line in northern Sweden, was analyzed to assess major changes in the structure and functioning of the aquatic ecosystem in response to climate change and tree-line dynamics. The compiled multi-proxy data, including sedimentary pigments, diatoms, chironomids, pollen, biogenic silica (BSi), carbon (C), nitrogen (N) elementa

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The remotely located Cambro-Ordovician strata in Ny Friesland, NE Spitsbergen, Svalbard, are referred to the Oslobreen Group, which is composed of the Tokammane, Kirtonryggen and Valhallfonna formations. Herein we record the conodont succession of the Kirtonryggen and Valhallfonna formations. Collections of well-preserved conodonts (CAI 1) have been recovered from the Lower to lower Middle Ordovic

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Integration of palynological proxies with annual lamina counting, C-14, Pb-210, Cs-137 and Am-241 radiometric dating, historical documents and old cadastral maps enabled reconstruction of changes in the cultural landscape resulting from extensive forest clearance, arable farming and slash-and-burn practices in South Estonia over the last millennium. Changes in land-cover were quantitatively recons