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The metabolite produced by one enzyme in a metabolic pathway can be transferred to the next enzyme in the pathway by free diffusion via solution or by channelling in an enzyme-enzyme complex without prior release of the metabolite to solution. While metabolite channelling is known to occur in systems where stable multienzyme complexes form, conflicting views have been expressed as to its existence

We present an object oriented environment for the design of neural network applications. The environment is based upon an object oriented database management system and includes a programming language suited for neural network simulations. In this language, it is easy to construct and modify complex network structures in a modular fashion. Usually, using an object oriented language would increase

The uprisings in the Middle East in 2011 had repercussions in Morocco too, where demonstrators demanded a reform of the political system. The king managed to diffuse the protests by presenting a new constitution which was accepted by 98,5 percent of the voters in a referendum in July 2011. While the new constitution introduces some limited restrictions on the king’s power, the bulk of executive po

Popular Abstract in Swedish Vanlig bagerijäst, Saccharomyces cerevisiae, används i storskalig etanol framställning från majs och sockerrör. Användandet av dessa råvaror för etanolproduktion konkurerar dock med framställning av spannmål för föda och djurhushållning. Den här avhandlingen har syftat till att få bagerijäst att använda sockerarten xylos, som finns i stora halter i restprodukter från skBaker’s yeast, Saccharomyces cerevisae, has been engineered to utilize the pentose sugar xylose present in lignocellulose biomass for the production of ethanol. Currently ethanol production from xylose is slow which limits the implementation of said strains in industrial production. This thesis describes the investigation of several metabolic aspects that control the rate of xylose utilization by

This thesis describes interactions that are salt-promoted and mainly based on the hydrophobicity of proteins. A series of variants of the green fluorescent protein (GFP) was first constructed by site-directed mutagenesis. Several tags with various properties were then genetically fused to the N-terminus of GFP. The protein variants constructed had small characteristic differences in hydrophobicity

Two separate Stroop-like paradigms with multimodal auditory and visual stimuli were presented. The results revealed a paradigm asymmetry where auditory stimuli resulted in a Stroop-like effect in both paradigms meanwhile visual stimuli only resulted in a Stroop-like effect in the colour-paradigm. The conclusion involved discussing the Working Memory attention and visual and auditory perceptual str