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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193186 hits

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The degradation of reinforced concrete (RC) structures has raised major concerns in the concrete industry. The demolition of existing structures has shown to be an unsustainable solution and leads to many financial concerns. Alternatively, the strengthening sector has put forward many sustainable solutions, such as the retrofitting and rehabilitation of existing structural elements with fiber-rein

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Background: Childhood cancer predisposition (ChiCaP) syndromes are increasingly recognized as contributing factors to childhood cancer development. Yet, due to variable availability of germline testing, many children with ChiCaP might go undetected today. We report results from the nationwide and prospective ChiCaP study that investigated diagnostic yield and clinical impact of integrating germlin

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The wide range of properties, relative ease and low cost of using Deep Eutectic Solvents garners them interest in an ever expanding range of applications. Among common DES components many are naturally occurring chiral molecules. Here we present the liquid structure of either single enantiomeric or racemic tartaric acid with choline chloride at a molar ratio of 2 choline chloride to 1 tartaric aci

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The reproductive-assurance hypothesis predicts that mating-system traits will evolve towards increased autonomous self-pollination in plant populations experiencing unreliable pollinator service. We tested this long-standing hypothesis by assessing geographic covariation among pollinator reliability, outcrossing rates, heterozygosity and relevant floral traits across populations of Dalechampia sca

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Strategy texts are an important way of communicating a strategy to a range of different stakeholders, including internal audiences as the organization communicates with itself (auto-communication). In this article, we analyze two related strategy texts that were produced for auto-communicative purposes as part of a strategic change initiative in a UK organization that employed a storytelling appro

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The effects of the medicinal plant rue (Ruta graveolens L.) on MS-related visual-field defects was tested. In five of nine patients the scotomata were reduced by a single dose of an aqueous extract of 3 g of the drug; the effect was reversible, appearing after only about two hours and lasting for one to two days. There was no detectable action in four patients. In no case were undesirable side eff

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Docking of mobile robots requires precise position measurements in relation to the docking platform to accomplish the task successfully. Besides, the pose estimation of the robot with the sensors in an indoor environment should be accurate enough for localization and navigation toward the docking platform. However, the sensor measurements are entitled to disturbances and measurement uncertainties.

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This study concerns digital diplomacy and the changing role of the diplomatic profession. By constructing a survey followed by descriptive in-depth interviews, this study demonstrates that Swedish diplomats have overall a positive view on social media’s role within the profession. The use of social media has increased the transparency of the profession and the citizen dialoge. Furthermore, this th

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Williams is a long standing, family owned and operated Formula 1 team. Their track record of success is closely tied to their status as a skilled and independent constructor in a highly competitive and monetized sport. When founder Frank Williams steps aside and his daughter Claire takes over, the team struggles to produce the glory of yesteryear. Claire’s appointment fuels accusations of nepotism

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Theory is still inconclusive to what level income inequality affects economic growth, with little research accounting for the effects of human development. The paper aimed to analyze both the effects of income inequality on growth while controlling for the underlying effects of different human development indicators. This was done by using data of 55 countries for the period 1990-2019, with result

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The construction of episodic memory is an automatic process. Event segmentation theory proposed that segmentation of the continuous perceptual stream into separate memory events occurs when changes in external boundaries lead to changes in internal perceptual and conceptual boundaries. The influence of perceptual and conceptual boundaries on episodic memory encoding has been the subject of intensi

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With fast technological development, Artificial Intelligence (AI) is one of the most revolutionary forces. Many organizations worldwide are adopting the technology, including the Swedish public sector and administration. Interviewing eight key informants who actively work with implementing AI into the Swedish public sector and administration structures, this thesis aims to investigate how they per

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Sweden was once known for its open and generous refugee reception, with a mindset that was different from its neighbouring countries. However, this has changed in recent years. Due to an increased influx of people seeking asylum in Sweden, restrictive measures were put in place. The political discourse on migration shifted from a welcoming narrative to enforcing border controls and limiting access

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With promulgation of a new constitution of Kenya in 2010, Kenya changed to a devolved system of governance after the general elections of 2013. Public Participation in Development was one aspect of democracy that Kenyans looked forward to in the new system of governance. This system was welcomed with optimism that distribution of resources equally among the 47 countries would do away with marginal

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Biological drugs such as tumor necrosis factor (TNFα) blockers are very successful and effective in therapy of chronic inflammatory disease. These blockers bind TNFα and inhibit its pro-inflammatory function. But unfortunately, biological drugs are immunogenic and prolonged treatment triggers the formation of anti-drug antibodies and neutralizing antibodies (NAbs). This reaction is associated with

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Antimalarial resistance has diminished the control over the spread of malaria worldwide. Initiated by the discovery of ferroquine, organometallic derivatives of chloroquine have been investigated against resistant strains of Plasmodium, but further work needs to be done. The aim of this project is to expand the available candidates of organometallic antimalarial drugs. In this project, six new org

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There are spatial elements and factors in every social activity. Physical environment in particular and its characteristics has a significant effect in the social decisions and outcomes of a location and of the residents of disadvantaged areas. These spatial elements and factors have been the main focus in many researches and studies about young people’s socio-economic statuses and achievements. T

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The aim of this thesis is to further develop the understanding of how different parameters related to the gasket groove of a heat exchanger affect the mechanical performance of the product. Three different parameters with two different gasket materials were evaluated. Comparisons between the parameters where mainly made in terms of contact- and leakage pressure but phenomena related to factors suc